FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2982603272> ?p ?o ?g. }

• W2982603272 abstract "KRAS mutations are reported in 20-25% of non-small cell lung cancer (NSCLC) and their prognostic role is unclear. We studied KRAS and EGFR genotyping in Greek NSCLC patients.KRAS and EGFR genotypes were centrally evaluated in 421 NSCLC patients (diagnosed September 1998 -June 2013) and associated with clinicopathological parameters. Outcome comparisons were performed in 288 patients receiving first line treatment.Most patients were male (78.6%), >60 years old (63.9%), current smokers (51.1%), with adenocarcinoma histology (63.9%). EGFR and KRAS mutations were found in 10.7% and 16.6% of all histologies, respectively, and in 14.9% and 21.9% of adenocarcinomas. At 4.5 years median follow-up, KRAS status was an independent negative prognostic factor for overall survival (OS, p=0.016). KRAS mutations conferred 80% increased risk of death in patients receiving first-line treatment (p=0.002).The presence of KRAS mutations is an independent negative prognosticator among Greek NSCLC patients and an independent response predictor to first line treatment." @default.
• W2982603272 created "2019-11-08" @default.
• W2982603272 creator A5001684767 @default.
• W2982603272 creator A5002833730 @default.
• W2982603272 creator A5004966307 @default.
• W2982603272 creator A5012112204 @default.
• W2982603272 creator A5012784345 @default.
• W2982603272 creator A5015478637 @default.
• W2982603272 creator A5033733633 @default.
• W2982603272 creator A5035312143 @default.
• W2982603272 creator A5041575636 @default.
• W2982603272 creator A5044610238 @default.
• W2982603272 creator A5047656028 @default.
• W2982603272 creator A5049075368 @default.
• W2982603272 creator A5050779584 @default.
• W2982603272 creator A5051871295 @default.
• W2982603272 creator A5053006338 @default.
• W2982603272 creator A5053915810 @default.
• W2982603272 creator A5064312934 @default.
• W2982603272 creator A5065143959 @default.
• W2982603272 creator A5085249624 @default.
• W2982603272 creator A5089476301 @default.
• W2982603272 date "2019-01-01" @default.
• W2982603272 modified "2023-09-27" @default.
• W2982603272 title "Genotyping KRAS and EGFR Mutations in Greek Patients With Non-small-cell Lung Cancer: Incidence, Significance and Implications for Treatment" @default.
• W2982603272 cites W1505261152 @default.
• W2982603272 cites W1590871522 @default.
• W2982603272 cites W1757407923 @default.
• W2982603272 cites W1879169560 @default.
• W2982603272 cites W1948677875 @default.
• W2982603272 cites W1974662648 @default.
• W2982603272 cites W1991874467 @default.
• W2982603272 cites W1994225895 @default.
• W2982603272 cites W1995594381 @default.
• W2982603272 cites W2018217352 @default.
• W2982603272 cites W2022995662 @default.
• W2982603272 cites W2029908992 @default.
• W2982603272 cites W2037475133 @default.
• W2982603272 cites W2041803801 @default.
• W2982603272 cites W2043696829 @default.
• W2982603272 cites W2055402151 @default.
• W2982603272 cites W2057209504 @default.
• W2982603272 cites W2058459763 @default.
• W2982603272 cites W2068423195 @default.
• W2982603272 cites W2073618702 @default.
• W2982603272 cites W2098272135 @default.
• W2982603272 cites W2114446999 @default.
• W2982603272 cites W2128059540 @default.
• W2982603272 cites W2141381346 @default.
• W2982603272 cites W2143138701 @default.
• W2982603272 cites W2150487560 @default.
• W2982603272 cites W2162159532 @default.
• W2982603272 cites W2166923287 @default.
• W2982603272 cites W2219662516 @default.
• W2982603272 cites W2238015728 @default.
• W2982603272 cites W2239287815 @default.
• W2982603272 cites W2251438188 @default.
• W2982603272 cites W2299214622 @default.
• W2982603272 cites W2301231481 @default.
• W2982603272 cites W2340056105 @default.
• W2982603272 cites W2341157401 @default.
• W2982603272 cites W2403654892 @default.
• W2982603272 cites W2530508394 @default.
• W2982603272 cites W2563174220 @default.
• W2982603272 cites W2567746986 @default.
• W2982603272 cites W2590660318 @default.
• W2982603272 cites W2593520371 @default.
• W2982603272 cites W2611896937 @default.
• W2982603272 doi "https://doi.org/10.21873/cgp.20155" @default.
• W2982603272 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6885370" @default.
• W2982603272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31659106" @default.
• W2982603272 hasPublicationYear "2019" @default.
• W2982603272 type Work @default.
• W2982603272 sameAs 2982603272 @default.
• W2982603272 citedByCount "4" @default.
• W2982603272 countsByYear W29826032722021 @default.
• W2982603272 crossrefType "journal-article" @default.
• W2982603272 hasAuthorship W2982603272A5001684767 @default.
• W2982603272 hasAuthorship W2982603272A5002833730 @default.
• W2982603272 hasAuthorship W2982603272A5004966307 @default.
• W2982603272 hasAuthorship W2982603272A5012112204 @default.
• W2982603272 hasAuthorship W2982603272A5012784345 @default.
• W2982603272 hasAuthorship W2982603272A5015478637 @default.
• W2982603272 hasAuthorship W2982603272A5033733633 @default.
• W2982603272 hasAuthorship W2982603272A5035312143 @default.
• W2982603272 hasAuthorship W2982603272A5041575636 @default.
• W2982603272 hasAuthorship W2982603272A5044610238 @default.
• W2982603272 hasAuthorship W2982603272A5047656028 @default.
• W2982603272 hasAuthorship W2982603272A5049075368 @default.
• W2982603272 hasAuthorship W2982603272A5050779584 @default.
• W2982603272 hasAuthorship W2982603272A5051871295 @default.
• W2982603272 hasAuthorship W2982603272A5053006338 @default.
• W2982603272 hasAuthorship W2982603272A5053915810 @default.
• W2982603272 hasAuthorship W2982603272A5064312934 @default.
• W2982603272 hasAuthorship W2982603272A5065143959 @default.
• W2982603272 hasAuthorship W2982603272A5085249624 @default.
• W2982603272 hasAuthorship W2982603272A5089476301 @default.
• W2982603272 hasBestOaLocation W29826032721 @default.
• W2982603272 hasConcept C104317684 @default.
• W2982603272 hasConcept C120665830 @default.

• next