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• W2982969721 abstract "It is now clear that access to specific metabolic programmes controls the survival and function of various immune cell populations, including T cells. Efficient naïve and memory T cell homoeostasis requires the use of specific metabolic pathways and differentiation requires rapid and dramatic metabolic remodelling. While we are beginning to appreciate the crucial role of metabolic programming during normal T cell physiology, many of the potential impacts of ageing on metabolic homoeostasis and remodelling in T cells remain unexplored. This review will outline our current understanding of T cell metabolism and explore age-related metabolic changes that are postulated or have been demonstrated to impact T cell function." @default.
• W2982969721 created "2019-11-22" @default.
• W2982969721 creator A5059050863 @default.
• W2982969721 creator A5065914860 @default.
• W2982969721 creator A5066451265 @default.
• W2982969721 creator A5070480232 @default.
• W2982969721 date "2019-01-01" @default.
• W2982969721 modified "2023-10-11" @default.
• W2982969721 title "The clock is ticking: the impact of ageing on T cell metabolism" @default.
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