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- W2983010367 endingPage "834" @default.
- W2983010367 startingPage "822" @default.
- W2983010367 abstract "Macrophages act as scavengers, modulating the immune response against pathogens and maintaining tissue homeostasis. Metabolism governs macrophage differentiation, polarization, mobilization, and the ability to mount an effective antitumor response. However, in cancer, the tumor microenvironment (TME) can actively reprogram macrophage metabolism either by direct exchange of metabolites or through cytokines and other signaling mediators. Thus, metabolic reprogramming holds potential for modulating macrophages and developing new therapeutic approaches. In this review, we provide an overview of macrophage metabolism as it relates to macrophage function and plasticity in cancer." @default.
- W2983010367 created "2019-11-22" @default.
- W2983010367 creator A5060280196 @default.
- W2983010367 creator A5067292361 @default.
- W2983010367 date "2019-12-01" @default.
- W2983010367 modified "2023-10-17" @default.
- W2983010367 title "Metabolic Regulation of Macrophage Polarization in Cancer" @default.
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