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- W2983100300 endingPage "104501" @default.
- W2983100300 startingPage "104501" @default.
- W2983100300 abstract "The broad role of stress in the brain-gut axis is widely acknowledged, with implications for multiple prevalent health conditions that are characterized by chronic gastrointestinal symptoms. These include the functional gastrointestinal disorders (FGID), such as irritable bowel syndrome and functional dyspepsia, as well as inflammatory bowel diseases (IBD) like ulcerative colitis and Crohn's disease. Although the afferent and efferent pathways linking the gut and the brain are modulated by stress, the fields of neurogastroenterology and psychoneuroendocrinology (PNE)/ psychoneuroimmunology (PNI) remain only loosely connected. We aim to contribute to bringing these fields closer together by drawing attention to a fascinating, evolving research area, targeting an audience with a strong interest in the role of stress in health and disease. To this end, this review introduces the concept of the brain-gut axis and its major pathways, and provides a brief introduction to epidemiological and clinical aspects of FGIDs and IBD. From an interdisciplinary PNE/PNI perspective, we then detail current knowledge regarding the role of chronic and acute stress in the pathophysiology of FGID and IBD. We provide an overview of evidence regarding non-pharmacological treatment approaches that target central or peripheral stress mechanisms, and conclude with future directions, particularly those arising from recent advances in the neurosciences and discoveries surrounding the gut microbiota." @default.
- W2983100300 created "2019-11-22" @default.
- W2983100300 creator A5007059796 @default.
- W2983100300 creator A5048053034 @default.
- W2983100300 creator A5054450534 @default.
- W2983100300 creator A5068155852 @default.
- W2983100300 date "2020-01-01" @default.
- W2983100300 modified "2023-10-10" @default.
- W2983100300 title "Stress and the brain-gut axis in functional and chronic-inflammatory gastrointestinal diseases: A transdisciplinary challenge" @default.
- W2983100300 cites W1008047686 @default.
- W2983100300 cites W1513442944 @default.
- W2983100300 cites W1553245692 @default.
- W2983100300 cites W1584010815 @default.
- W2983100300 cites W1664843084 @default.
- W2983100300 cites W1963704444 @default.
- W2983100300 cites W1966160259 @default.
- W2983100300 cites W1967763922 @default.
- W2983100300 cites W1967976394 @default.
- W2983100300 cites W1974161819 @default.
- W2983100300 cites W1975033451 @default.
- W2983100300 cites W1976351465 @default.
- W2983100300 cites W1976863879 @default.
- W2983100300 cites W1982056870 @default.
- W2983100300 cites W1982962172 @default.
- W2983100300 cites W1983233325 @default.
- W2983100300 cites W1984630897 @default.
- W2983100300 cites W1986792124 @default.
- W2983100300 cites W1987715985 @default.
- W2983100300 cites W1989009190 @default.
- W2983100300 cites W1989227965 @default.
- W2983100300 cites W1990035773 @default.
- W2983100300 cites W1993678078 @default.
- W2983100300 cites W2002883464 @default.
- W2983100300 cites W2002912688 @default.
- W2983100300 cites W2003134135 @default.
- W2983100300 cites W2007290569 @default.
- W2983100300 cites W2009710456 @default.
- W2983100300 cites W2010088553 @default.
- W2983100300 cites W2015760421 @default.
- W2983100300 cites W2016614920 @default.
- W2983100300 cites W2022138544 @default.
- W2983100300 cites W2022434467 @default.
- W2983100300 cites W2033892467 @default.
- W2983100300 cites W2034003089 @default.
- W2983100300 cites W2035716309 @default.
- W2983100300 cites W2042570237 @default.
- W2983100300 cites W2043091714 @default.
- W2983100300 cites W2046123368 @default.
- W2983100300 cites W2047170682 @default.
- W2983100300 cites W2047220967 @default.
- W2983100300 cites W2048545464 @default.
- W2983100300 cites W2057486852 @default.
- W2983100300 cites W2057539040 @default.
- W2983100300 cites W2058197277 @default.
- W2983100300 cites W2062788711 @default.
- W2983100300 cites W2062895844 @default.
- W2983100300 cites W2065638022 @default.
- W2983100300 cites W2065994153 @default.
- W2983100300 cites W2066281651 @default.
- W2983100300 cites W2067949717 @default.
- W2983100300 cites W2069806103 @default.
- W2983100300 cites W2072004231 @default.
- W2983100300 cites W2072868075 @default.
- W2983100300 cites W2073684276 @default.
- W2983100300 cites W2073794207 @default.
- W2983100300 cites W2075530811 @default.
- W2983100300 cites W2078465762 @default.
- W2983100300 cites W2080898952 @default.
- W2983100300 cites W2082214913 @default.
- W2983100300 cites W2082901516 @default.
- W2983100300 cites W2083186369 @default.
- W2983100300 cites W2085766624 @default.
- W2983100300 cites W2086246203 @default.
- W2983100300 cites W2087180433 @default.
- W2983100300 cites W2091338428 @default.
- W2983100300 cites W2092717271 @default.
- W2983100300 cites W2101159205 @default.
- W2983100300 cites W2101601471 @default.
- W2983100300 cites W2102567329 @default.
- W2983100300 cites W2102662093 @default.
- W2983100300 cites W2102865615 @default.
- W2983100300 cites W2109774784 @default.
- W2983100300 cites W2111792249 @default.
- W2983100300 cites W2112636046 @default.
- W2983100300 cites W2113842526 @default.
- W2983100300 cites W2117139515 @default.
- W2983100300 cites W2124259409 @default.
- W2983100300 cites W2125619655 @default.
- W2983100300 cites W2126795224 @default.
- W2983100300 cites W2130694546 @default.
- W2983100300 cites W2131798536 @default.
- W2983100300 cites W2143364563 @default.
- W2983100300 cites W2144961120 @default.
- W2983100300 cites W2145165361 @default.
- W2983100300 cites W2147854285 @default.
- W2983100300 cites W2152336072 @default.
- W2983100300 cites W2156744949 @default.
- W2983100300 cites W2157275283 @default.