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- W2983143513 endingPage "112640" @default.
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- W2983143513 abstract "Information of the modulation effect of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) on post-traumatic stress disorder (PTSD) after earthquakes is scarce and contradictory. A cross-sectional face-to-face interview survey of a representative sample of the adults was carried out after the Lorca (Spain) earthquakes (May 11, 2011). Socio-demographic variables, DSM-IV diagnostic assessment and earthquake-related stressors were obtained from the Composite International Diagnostic Interview (CIDI). The triallelic and biallelic classification of the 5-HTTLPR polymorphism were genotyped from buccal swabs. Multivariate logistic regression models were used to predict PTSD, including interaction terms to explore gene-environment (G x E) interactions. The vast majority (83%, n = 341) of the Lorca survey respondents (n = 412, 71% response rate) were genotyped. Both classifications of the 5-HTTLPR genotype were in Hardy-Weinberg equilibrium. Prior lifetime PTSD was the only variable that remained a significant predictor after adjustments. There were no significant main effects of earthquake related stressors or 5-HTTLPR. However, G x E interactions of 5-HTTLPR with high emotional impact and prior lifetime anxiety disorders were statistically significant. These results provide new evidence of the modulation effect of the 5-HTTLPR polymorphisms on PTSD risk. This information might characterize people at higher risk of developing PTSD after an earthquake exposure." @default.
- W2983143513 created "2019-11-22" @default.
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- W2983143513 date "2019-12-01" @default.
- W2983143513 modified "2023-10-06" @default.
- W2983143513 title "Modification of the risk of post-traumatic stress disorder (PTSD) by the 5-HTTLPR polymorphisms after Lorca's earthquakes (Murcia, Spain)." @default.
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- W2983143513 cites W1848819387 @default.
- W2983143513 cites W1878248448 @default.
- W2983143513 cites W1967287454 @default.
- W2983143513 cites W1976730458 @default.
- W2983143513 cites W1977354406 @default.
- W2983143513 cites W1977949510 @default.
- W2983143513 cites W1984486655 @default.
- W2983143513 cites W1986306870 @default.
- W2983143513 cites W2004435166 @default.
- W2983143513 cites W2007963396 @default.
- W2983143513 cites W2016460448 @default.
- W2983143513 cites W2019883630 @default.
- W2983143513 cites W2022032719 @default.
- W2983143513 cites W2022871897 @default.
- W2983143513 cites W2023136414 @default.
- W2983143513 cites W2023603356 @default.
- W2983143513 cites W2027970575 @default.
- W2983143513 cites W2029445248 @default.
- W2983143513 cites W2033080823 @default.
- W2983143513 cites W2035724435 @default.
- W2983143513 cites W2038134753 @default.
- W2983143513 cites W2050237761 @default.
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- W2983143513 cites W2054214203 @default.
- W2983143513 cites W2063022574 @default.
- W2983143513 cites W2072026981 @default.
- W2983143513 cites W2072260750 @default.
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- W2983143513 cites W2077086070 @default.
- W2983143513 cites W2079160624 @default.
- W2983143513 cites W2100230238 @default.
- W2983143513 cites W2101053942 @default.
- W2983143513 cites W2103939554 @default.
- W2983143513 cites W2106095564 @default.
- W2983143513 cites W2108697560 @default.
- W2983143513 cites W2109026965 @default.
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- W2983143513 cites W2115609473 @default.
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- W2983143513 cites W2118561015 @default.
- W2983143513 cites W2118826874 @default.
- W2983143513 cites W2126983199 @default.
- W2983143513 cites W2147847810 @default.
- W2983143513 cites W2151357909 @default.
- W2983143513 cites W2152247590 @default.
- W2983143513 cites W2155075770 @default.
- W2983143513 cites W2158628761 @default.
- W2983143513 cites W2160854040 @default.
- W2983143513 cites W2173765887 @default.
- W2983143513 cites W2190190297 @default.
- W2983143513 cites W2231695800 @default.
- W2983143513 cites W2415716286 @default.
- W2983143513 cites W2509386772 @default.
- W2983143513 cites W2604674575 @default.
- W2983143513 cites W2605617475 @default.
- W2983143513 cites W2610359325 @default.
- W2983143513 cites W2736823191 @default.
- W2983143513 cites W2740846930 @default.
- W2983143513 cites W2754145602 @default.
- W2983143513 cites W2770355505 @default.
- W2983143513 cites W2780843692 @default.
- W2983143513 cites W2793283442 @default.
- W2983143513 cites W2969256198 @default.
- W2983143513 cites W4211189621 @default.
- W2983143513 cites W4230810535 @default.
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- W2983143513 doi "https://doi.org/10.1016/j.psychres.2019.112640" @default.
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