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- W2983160561 abstract "Abstract Introduction Hypereosinophilic syndrome (HES) is a very heterogeneous group of disorders with varied etiologies characterized by peripheral eosinophilia and eosinophilic tissue/end‐organ damage. Three‐dimensional speckle‐tracking echocardiography (3DSTE) was used for assessment of left ventricular (LV) rotational mechanics in HES patients. Methods The study comprised 13 HES patients, from which one patient was excluded due to insufficient image quality. The remaining patient population consisted of 12 HES cases (mean age: 59.7 ± 13.7 years, eight males). The control group consisted of 36 healthy volunteers (mean age: 52.9 ± 8.3 years, 23 males). 3DSTE was used for the evaluation of LV rotational abnormalities. Results Both LV apical rotation (4.86 ± 1.92 degree vs 10.07 ± 3.92 degree, P < .0001) and LV twist (8.52 ± 2.79 degree vs 14.41 ± 4.26 degree, P < .0001) showed significant deteriorations in most of HES patients. Time‐to‐peak LV apical rotation (380 ± 115 ms vs 344 ± 69 ms, P = .56), LV basal rotation (335 ± 148 ms vs 337 ± 111 ms, P = .89), and LV twist (348 ± 91 ms vs 320 ± 60 ms, P = .64) were not significantly different between HES patients and controls. No correlations could be detected between absolute eosinophil count and eosinophil ratio and apical LV rotation ( r = 0.12, P = .51 and r = 0.23, P = .45, respectively) and LV twist ( r = 0.24, P = .39 and r = 0.31, P = .34, respectively). In two subjects, the absence of LV twist called LV “rigid body rotation” (RBR) was detected. Conclusions Reduced LV apical rotation and twist could be demonstrated in HES. LV‐RBR could be detected in some HES patients." @default.
- W2983160561 created "2019-11-22" @default.
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- W2983160561 date "2019-11-01" @default.
- W2983160561 modified "2023-10-16" @default.
- W2983160561 title "Left ventricular rotational mechanics in hypereosinophilic syndrome—Analysis from the three‐dimensional speckle‐tracking echocardiographic MAGYAR‐Path Study" @default.
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- W2983160561 doi "https://doi.org/10.1111/echo.14517" @default.
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