Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983502716> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2983502716 endingPage "64" @default.
- W2983502716 startingPage "51" @default.
- W2983502716 abstract "Abstract Enzymatically generated reactive species are emerging as endogenous signaling molecules, targeting specific thiol/metal redox switches in proteins and organelles, thereby affecting cell metabolism and survival. To better characterize the complex network of interactions of reactive species with themselves and their biological targets and to understand their significance for metabolic control, we recently introduced the “reactive species interactome” (RSI) concept. The RSI is a primeval redox system that connects the (bio)chemical pathways that generate reactive species with cellular intermediary metabolism, bioenergetics, and the extracellular environment. The main characteristics of the RSI are (a) robustness and flexibility, (b) adaptability and rapid responsiveness, and (c) the ability to sense the chemical composition of intra- and extracellular milieu. These properties enable cells/organs to communicate and sense and adapt to changes in environmental conditions and metabolic demand. As conceptual framework, the RSI may enable to better understand how complex life forms operate and respond to challenges at the whole organism level, potentially enabling us to harness this information for medical use in health and disease." @default.
- W2983502716 created "2019-11-22" @default.
- W2983502716 creator A5001512888 @default.
- W2983502716 creator A5017139036 @default.
- W2983502716 creator A5036280404 @default.
- W2983502716 creator A5062165317 @default.
- W2983502716 creator A5064382422 @default.
- W2983502716 date "2020-01-01" @default.
- W2983502716 modified "2023-10-13" @default.
- W2983502716 title "The reactive species interactome" @default.
- W2983502716 cites W1971256361 @default.
- W2983502716 cites W1990139307 @default.
- W2983502716 cites W1997023449 @default.
- W2983502716 cites W2017521727 @default.
- W2983502716 cites W2020247531 @default.
- W2983502716 cites W2032839609 @default.
- W2983502716 cites W2033007699 @default.
- W2983502716 cites W2040148126 @default.
- W2983502716 cites W2058137293 @default.
- W2983502716 cites W2077103811 @default.
- W2983502716 cites W2079911719 @default.
- W2983502716 cites W2093742700 @default.
- W2983502716 cites W2097996389 @default.
- W2983502716 cites W2111363155 @default.
- W2983502716 cites W2134093049 @default.
- W2983502716 cites W2191665487 @default.
- W2983502716 cites W2220298324 @default.
- W2983502716 cites W2284168863 @default.
- W2983502716 cites W2338216283 @default.
- W2983502716 cites W2340137273 @default.
- W2983502716 cites W2593033949 @default.
- W2983502716 cites W2605928831 @default.
- W2983502716 cites W2613154641 @default.
- W2983502716 cites W2614388806 @default.
- W2983502716 cites W2768440581 @default.
- W2983502716 cites W2802985983 @default.
- W2983502716 cites W2911470473 @default.
- W2983502716 cites W2919487732 @default.
- W2983502716 cites W2934698633 @default.
- W2983502716 cites W2939371872 @default.
- W2983502716 doi "https://doi.org/10.1016/b978-0-12-818606-0.00004-3" @default.
- W2983502716 hasPublicationYear "2020" @default.
- W2983502716 type Work @default.
- W2983502716 sameAs 2983502716 @default.
- W2983502716 citedByCount "3" @default.
- W2983502716 countsByYear W29835027162020 @default.
- W2983502716 countsByYear W29835027162021 @default.
- W2983502716 crossrefType "book-chapter" @default.
- W2983502716 hasAuthorship W2983502716A5001512888 @default.
- W2983502716 hasAuthorship W2983502716A5017139036 @default.
- W2983502716 hasAuthorship W2983502716A5036280404 @default.
- W2983502716 hasAuthorship W2983502716A5062165317 @default.
- W2983502716 hasAuthorship W2983502716A5064382422 @default.
- W2983502716 hasConcept C104317684 @default.
- W2983502716 hasConcept C205649164 @default.
- W2983502716 hasConcept C54355233 @default.
- W2983502716 hasConcept C70721500 @default.
- W2983502716 hasConcept C86803240 @default.
- W2983502716 hasConcept C9760119 @default.
- W2983502716 hasConceptScore W2983502716C104317684 @default.
- W2983502716 hasConceptScore W2983502716C205649164 @default.
- W2983502716 hasConceptScore W2983502716C54355233 @default.
- W2983502716 hasConceptScore W2983502716C70721500 @default.
- W2983502716 hasConceptScore W2983502716C86803240 @default.
- W2983502716 hasConceptScore W2983502716C9760119 @default.
- W2983502716 hasLocation W29835027161 @default.
- W2983502716 hasLocation W29835027162 @default.
- W2983502716 hasLocation W29835027163 @default.
- W2983502716 hasOpenAccess W2983502716 @default.
- W2983502716 hasPrimaryLocation W29835027161 @default.
- W2983502716 hasRelatedWork W1982038138 @default.
- W2983502716 hasRelatedWork W2007507741 @default.
- W2983502716 hasRelatedWork W2034246622 @default.
- W2983502716 hasRelatedWork W2169777166 @default.
- W2983502716 hasRelatedWork W2748952813 @default.
- W2983502716 hasRelatedWork W2899084033 @default.
- W2983502716 hasRelatedWork W2979636089 @default.
- W2983502716 hasRelatedWork W3005984791 @default.
- W2983502716 hasRelatedWork W4292634579 @default.
- W2983502716 hasRelatedWork W4377194874 @default.
- W2983502716 isParatext "false" @default.
- W2983502716 isRetracted "false" @default.
- W2983502716 magId "2983502716" @default.
- W2983502716 workType "book-chapter" @default.