Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983592652> ?p ?o ?g. }
- W2983592652 endingPage "113" @default.
- W2983592652 startingPage "107" @default.
- W2983592652 abstract "Spontaneous and sensory-evoked activity propagates across varying spatial scales in the mammalian cortex, but technical challenges have limited conceptual links between the function of local neuronal circuits and brain-wide network dynamics. We present a method for simultaneous cellular-resolution two-photon calcium imaging of a local microcircuit and mesoscopic widefield calcium imaging of the entire cortical mantle in awake mice. Our multi-scale approach involves a microscope with an orthogonal axis design where the mesoscopic objective is oriented above the brain and the two-photon objective is oriented horizontally, with imaging performed through a microprism. We also introduce a viral transduction method for robust and widespread gene delivery in the mouse brain. These approaches allow us to identify the behavioral state-dependent functional connectivity of pyramidal neurons and vasoactive intestinal peptide-expressing interneurons with long-range cortical networks. Our imaging system provides a powerful strategy for investigating cortical architecture across a wide range of spatial scales." @default.
- W2983592652 created "2019-11-22" @default.
- W2983592652 creator A5007885732 @default.
- W2983592652 creator A5009124607 @default.
- W2983592652 creator A5023272498 @default.
- W2983592652 creator A5031151569 @default.
- W2983592652 creator A5057862535 @default.
- W2983592652 creator A5073499106 @default.
- W2983592652 creator A5079635112 @default.
- W2983592652 creator A5084684839 @default.
- W2983592652 date "2019-11-04" @default.
- W2983592652 modified "2023-10-18" @default.
- W2983592652 title "Simultaneous mesoscopic and two-photon imaging of neuronal activity in cortical circuits" @default.
- W2983592652 cites W1583675730 @default.
- W2983592652 cites W1860783201 @default.
- W2983592652 cites W1895368383 @default.
- W2983592652 cites W1975032719 @default.
- W2983592652 cites W1975389666 @default.
- W2983592652 cites W2031676034 @default.
- W2983592652 cites W2040574649 @default.
- W2983592652 cites W2042662796 @default.
- W2983592652 cites W2050215536 @default.
- W2983592652 cites W2067684298 @default.
- W2983592652 cites W2068809501 @default.
- W2983592652 cites W2074257329 @default.
- W2983592652 cites W2076443641 @default.
- W2983592652 cites W2081997665 @default.
- W2983592652 cites W2085561705 @default.
- W2983592652 cites W2086338669 @default.
- W2983592652 cites W2089823661 @default.
- W2983592652 cites W2097237250 @default.
- W2983592652 cites W2104135721 @default.
- W2983592652 cites W2109062476 @default.
- W2983592652 cites W2166739815 @default.
- W2983592652 cites W2171332611 @default.
- W2983592652 cites W2179178098 @default.
- W2983592652 cites W2195364602 @default.
- W2983592652 cites W2211009999 @default.
- W2983592652 cites W2231009150 @default.
- W2983592652 cites W2259648020 @default.
- W2983592652 cites W2295718126 @default.
- W2983592652 cites W2333846070 @default.
- W2983592652 cites W2394641095 @default.
- W2983592652 cites W2411528277 @default.
- W2983592652 cites W2469581795 @default.
- W2983592652 cites W2472683490 @default.
- W2983592652 cites W2503929286 @default.
- W2983592652 cites W2513047215 @default.
- W2983592652 cites W2524300278 @default.
- W2983592652 cites W2584632106 @default.
- W2983592652 cites W2616012590 @default.
- W2983592652 cites W2708579841 @default.
- W2983592652 cites W2767493192 @default.
- W2983592652 cites W2773803332 @default.
- W2983592652 cites W2794495549 @default.
- W2983592652 cites W2883891044 @default.
- W2983592652 cites W2890927907 @default.
- W2983592652 cites W2891530389 @default.
- W2983592652 cites W2896499120 @default.
- W2983592652 cites W2899201459 @default.
- W2983592652 cites W2911231124 @default.
- W2983592652 cites W2921173903 @default.
- W2983592652 cites W2952059832 @default.
- W2983592652 cites W2953100281 @default.
- W2983592652 cites W3099323463 @default.
- W2983592652 cites W648226467 @default.
- W2983592652 cites W2179173002 @default.
- W2983592652 doi "https://doi.org/10.1038/s41592-019-0625-2" @default.
- W2983592652 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6946863" @default.
- W2983592652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31686040" @default.
- W2983592652 hasPublicationYear "2019" @default.
- W2983592652 type Work @default.
- W2983592652 sameAs 2983592652 @default.
- W2983592652 citedByCount "89" @default.
- W2983592652 countsByYear W29835926522019 @default.
- W2983592652 countsByYear W29835926522020 @default.
- W2983592652 countsByYear W29835926522021 @default.
- W2983592652 countsByYear W29835926522022 @default.
- W2983592652 countsByYear W29835926522023 @default.
- W2983592652 crossrefType "journal-article" @default.
- W2983592652 hasAuthorship W2983592652A5007885732 @default.
- W2983592652 hasAuthorship W2983592652A5009124607 @default.
- W2983592652 hasAuthorship W2983592652A5023272498 @default.
- W2983592652 hasAuthorship W2983592652A5031151569 @default.
- W2983592652 hasAuthorship W2983592652A5057862535 @default.
- W2983592652 hasAuthorship W2983592652A5073499106 @default.
- W2983592652 hasAuthorship W2983592652A5079635112 @default.
- W2983592652 hasAuthorship W2983592652A5084684839 @default.
- W2983592652 hasBestOaLocation W29835926522 @default.
- W2983592652 hasConcept C118403218 @default.
- W2983592652 hasConcept C120665830 @default.
- W2983592652 hasConcept C121332964 @default.
- W2983592652 hasConcept C169760540 @default.
- W2983592652 hasConcept C177731217 @default.
- W2983592652 hasConcept C178790620 @default.
- W2983592652 hasConcept C185592680 @default.
- W2983592652 hasConcept C2776032975 @default.
- W2983592652 hasConcept C2777348757 @default.