FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983604384> ?p ?o ?g. }

• W2983604384 abstract "Due to the aquatic animal pathogens are numerous and specific, the pathogen invasion mechanisms are more complicated. The cell surface receptors play vital roles to understand these mechanisms. Syndecan is a cell surface protein and could function as a receptor involved bacteria and virus infections. But there are few studies on the function of syndecan in shrimp and their interaction with aquatic bacterial pathogens. In the present study, we identified a syndecan receptor gene from Macrobrachium rosenbergii and analyzed its functions during the bacterial infections. The MrSDC was expressed in various tissues and presented a constitutive expression distribution except in eyestalk. Recombinant MrSDC-his tag protein was expressed in the E. coli BL21 with pET30a/MrSDC plasmid and exhibited a broad bacterial binding activities. The inhibition of MrSDC expression by dsRNA interference and antibody blocked could significantly reduce the number of Aeromonas hydrophila in hepatopancreas compared with the control. The overexpression of MrSDC by mRNA injection could significantly increase the number of A. hydrophila. In addition, the functional role of syndecan heparan sulfate chains in bacterial recognition was also studied. After extra injection of heparan sulfate in vivo, the bacterial numbers and accumulative mortality of M. rosenbergii were significantly higher than control groups and exhibit a dose effect. All these data could indicate that the cell surface syndecan protein could function as mediator in bacterial infections by the heparan sulfate chains. Our present study will provide new insights into the functions of shrimp syndecan." @default.
• W2983604384 created "2019-11-22" @default.
• W2983604384 creator A5008902942 @default.
• W2983604384 creator A5020400987 @default.
• W2983604384 creator A5028179790 @default.
• W2983604384 creator A5040272142 @default.
• W2983604384 creator A5065236570 @default.
• W2983604384 creator A5067315531 @default.
• W2983604384 date "2020-01-01" @default.
• W2983604384 modified "2023-09-24" @default.
• W2983604384 title "The surface syndecan protein from Macrobrachium rosenbergii could function as mediator in bacterial infections" @default.
• W2983604384 cites W1484612874 @default.
• W2983604384 cites W1569955072 @default.
• W2983604384 cites W1714312197 @default.
• W2983604384 cites W1963709999 @default.
• W2983604384 cites W1964954110 @default.
• W2983604384 cites W1966060588 @default.
• W2983604384 cites W1971060969 @default.
• W2983604384 cites W1971373148 @default.
• W2983604384 cites W1978656670 @default.
• W2983604384 cites W1990306722 @default.
• W2983604384 cites W2001087258 @default.
• W2983604384 cites W2009144084 @default.
• W2983604384 cites W2025124945 @default.
• W2983604384 cites W2031143008 @default.
• W2983604384 cites W2031675363 @default.
• W2983604384 cites W2033093592 @default.
• W2983604384 cites W2033617388 @default.
• W2983604384 cites W2037554676 @default.
• W2983604384 cites W2041649294 @default.
• W2983604384 cites W2042177179 @default.
• W2983604384 cites W2048493811 @default.
• W2983604384 cites W2049624297 @default.
• W2983604384 cites W2058825541 @default.
• W2983604384 cites W2062011023 @default.
• W2983604384 cites W2073742636 @default.
• W2983604384 cites W2096413300 @default.
• W2983604384 cites W2102803142 @default.
• W2983604384 cites W2103048323 @default.
• W2983604384 cites W2113266466 @default.
• W2983604384 cites W2114950491 @default.
• W2983604384 cites W2123277882 @default.
• W2983604384 cites W2135747811 @default.
• W2983604384 cites W2141902086 @default.
• W2983604384 cites W2141930155 @default.
• W2983604384 cites W2146074826 @default.
• W2983604384 cites W2151524600 @default.
• W2983604384 cites W2160067797 @default.
• W2983604384 cites W2299755521 @default.
• W2983604384 cites W2342313938 @default.
• W2983604384 cites W53099270 @default.
• W2983604384 doi "https://doi.org/10.1016/j.fsi.2019.11.012" @default.
• W2983604384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31704203" @default.
• W2983604384 hasPublicationYear "2020" @default.
• W2983604384 type Work @default.
• W2983604384 sameAs 2983604384 @default.
• W2983604384 citedByCount "0" @default.
• W2983604384 crossrefType "journal-article" @default.
• W2983604384 hasAuthorship W2983604384A5008902942 @default.
• W2983604384 hasAuthorship W2983604384A5020400987 @default.
• W2983604384 hasAuthorship W2983604384A5028179790 @default.
• W2983604384 hasAuthorship W2983604384A5040272142 @default.
• W2983604384 hasAuthorship W2983604384A5065236570 @default.
• W2983604384 hasAuthorship W2983604384A5067315531 @default.
• W2983604384 hasConcept C1491633281 @default.
• W2983604384 hasConcept C170493617 @default.
• W2983604384 hasConcept C2775995008 @default.
• W2983604384 hasConcept C2776115401 @default.
• W2983604384 hasConcept C2778041096 @default.
• W2983604384 hasConcept C2779441561 @default.
• W2983604384 hasConcept C505870484 @default.
• W2983604384 hasConcept C523546767 @default.
• W2983604384 hasConcept C54355233 @default.
• W2983604384 hasConcept C55493867 @default.
• W2983604384 hasConcept C65001120 @default.
• W2983604384 hasConcept C86803240 @default.
• W2983604384 hasConcept C89423630 @default.
• W2983604384 hasConcept C95444343 @default.
• W2983604384 hasConceptScore W2983604384C1491633281 @default.
• W2983604384 hasConceptScore W2983604384C170493617 @default.
• W2983604384 hasConceptScore W2983604384C2775995008 @default.
• W2983604384 hasConceptScore W2983604384C2776115401 @default.
• W2983604384 hasConceptScore W2983604384C2778041096 @default.
• W2983604384 hasConceptScore W2983604384C2779441561 @default.
• W2983604384 hasConceptScore W2983604384C505870484 @default.
• W2983604384 hasConceptScore W2983604384C523546767 @default.
• W2983604384 hasConceptScore W2983604384C54355233 @default.
• W2983604384 hasConceptScore W2983604384C55493867 @default.
• W2983604384 hasConceptScore W2983604384C65001120 @default.
• W2983604384 hasConceptScore W2983604384C86803240 @default.
• W2983604384 hasConceptScore W2983604384C89423630 @default.
• W2983604384 hasConceptScore W2983604384C95444343 @default.
• W2983604384 hasFunder F4320321001 @default.
• W2983604384 hasFunder F4320322769 @default.
• W2983604384 hasLocation W29836043841 @default.
• W2983604384 hasLocation W29836043842 @default.
• W2983604384 hasOpenAccess W2983604384 @default.
• W2983604384 hasPrimaryLocation W29836043841 @default.
• W2983604384 hasRelatedWork W1964067222 @default.
• W2983604384 hasRelatedWork W2057103288 @default.

• next