FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983609562> ?p ?o ?g. }

• W2983609562 endingPage "141" @default.
• W2983609562 startingPage "132" @default.
• W2983609562 abstract "Objective -to identify the role of occupational hazards (OH) as a risk factor of onset and unfavorable outcome of coronary artery disease (CAD). Retrospective study included analysis of 307 case reports of CAD patients, including 59 patients with long term history of OH exposure. Prospective study included observation of 244 STEMI patients during their in-patient treatment, including 113 patients with prior exposure to OH. OH were demonstrated to contribute to the risk of CAD, and to be directly involved in atherosclerotic coronary artery (CA) injury, its role being equal to that of the classical risk factors, such as arterial hypertension (AH), dyslipidemia, and diabetes mellitus (DM). As shown by regression analysis, AH, DM, and dyslipidemia primarily promote atherogenesis in second and third order CA, while technogenic xenobiotics - mostly in first and second order CA, including the left CA truncus. History of OH directly affects the degree of stenosis, along with such important factors as LDL cholesterol, HDL cholesterol, triglycerides, and AH. According to Caplan-Meyer curves, OH exposure affects the hospital course of STEMI due to the adverse impact of technogenic xenobiotics leading, which contributes to the main mechanisms of CAD progression. In these patients the activity of systemic inflammation is higher, endothelial dysfunction, and autonomic disbalance and heterogeneity of myocardial repolarization are more profound. More pronounced remodeling of left ventricle, which is apparently due to the pre-existing abnormalities of cardiomyocytes caused by the long term effect of technogenic xenobiotics, significantly impairs the functional condition of myocardium, and accordingly the patient's prognosis. Our data suggest occupational hazards as a risk factor for onset and progression of CAD. Further studies involving this patient category are necessary." @default.
• W2983609562 created "2019-11-22" @default.
• W2983609562 creator A5031660197 @default.
• W2983609562 creator A5045041487 @default.
• W2983609562 creator A5061957247 @default.
• W2983609562 creator A5075609842 @default.
• W2983609562 creator A5086572118 @default.
• W2983609562 date "2018-02-01" @default.
• W2983609562 modified "2023-09-27" @default.
• W2983609562 title "OCCUPATIONAL HAZARDS AS A RISK FACTOR OF ONSET AND UNFAVORABLE OUTCOME OF ISCHEMIC HEART DISEASE." @default.
• W2983609562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29578439" @default.
• W2983609562 hasPublicationYear "2018" @default.
• W2983609562 type Work @default.
• W2983609562 sameAs 2983609562 @default.
• W2983609562 citedByCount "0" @default.
• W2983609562 crossrefType "journal-article" @default.
• W2983609562 hasAuthorship W2983609562A5031660197 @default.
• W2983609562 hasAuthorship W2983609562A5045041487 @default.
• W2983609562 hasAuthorship W2983609562A5061957247 @default.
• W2983609562 hasAuthorship W2983609562A5075609842 @default.
• W2983609562 hasAuthorship W2983609562A5086572118 @default.
• W2983609562 hasConcept C126322002 @default.
• W2983609562 hasConcept C134018914 @default.
• W2983609562 hasConcept C164705383 @default.
• W2983609562 hasConcept C2778096610 @default.
• W2983609562 hasConcept C2778213512 @default.
• W2983609562 hasConcept C2778921608 @default.
• W2983609562 hasConcept C2779134260 @default.
• W2983609562 hasConcept C2780007028 @default.
• W2983609562 hasConcept C2780972559 @default.
• W2983609562 hasConcept C50440223 @default.
• W2983609562 hasConcept C555293320 @default.
• W2983609562 hasConcept C71924100 @default.
• W2983609562 hasConceptScore W2983609562C126322002 @default.
• W2983609562 hasConceptScore W2983609562C134018914 @default.
• W2983609562 hasConceptScore W2983609562C164705383 @default.
• W2983609562 hasConceptScore W2983609562C2778096610 @default.
• W2983609562 hasConceptScore W2983609562C2778213512 @default.
• W2983609562 hasConceptScore W2983609562C2778921608 @default.
• W2983609562 hasConceptScore W2983609562C2779134260 @default.
• W2983609562 hasConceptScore W2983609562C2780007028 @default.
• W2983609562 hasConceptScore W2983609562C2780972559 @default.
• W2983609562 hasConceptScore W2983609562C50440223 @default.
• W2983609562 hasConceptScore W2983609562C555293320 @default.
• W2983609562 hasConceptScore W2983609562C71924100 @default.
• W2983609562 hasIssue "Issue" @default.
• W2983609562 hasLocation W29836095621 @default.
• W2983609562 hasOpenAccess W2983609562 @default.
• W2983609562 hasPrimaryLocation W29836095621 @default.
• W2983609562 hasRelatedWork W2050431722 @default.
• W2983609562 hasRelatedWork W2052627450 @default.
• W2983609562 hasRelatedWork W2065525860 @default.
• W2983609562 hasRelatedWork W2071647681 @default.
• W2983609562 hasRelatedWork W2085432200 @default.
• W2983609562 hasRelatedWork W2143132479 @default.
• W2983609562 hasRelatedWork W2388932867 @default.
• W2983609562 hasRelatedWork W3112891903 @default.
• W2983609562 hasRelatedWork W3141700921 @default.
• W2983609562 hasRelatedWork W4229452857 @default.
• W2983609562 isParatext "false" @default.
• W2983609562 isRetracted "false" @default.
• W2983609562 magId "2983609562" @default.
• W2983609562 workType "article" @default.