FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983669283> ?p ?o ?g. }

• W2983669283 abstract "Abstract Bowel microbiota is a “metaorgan” of metabolisms on which quantitative readouts must be performed before interventions can be introduced and evaluated. The study of the effects of probiotic Clostridium butyricum MIYAIRI 588 ( CBM588 ) on intestine transplantees indicated an increased percentage of the “other glycan degradation” pathway in 16S-rRNA-inferred metagenomes. To verify the prediction, a scoring system of carbohydrate metabolisms derived from shotgun metagenomes was developed using hidden Markov models. A significant correlation (R = 0.9, p < 0.015) between both modalities was demonstrated. An independent validation revealed a strong complementarity (R = −0.97, p < 0.002) between the scores and the abundance of “glycogen degradation” in bacteria communities. On applying the system to bacteria genomes, CBM588 had only 1 match and ranked higher than the other 8 bacteria evaluated. The gram-stain properties were significantly correlated to the scores ( p < 5 × 10 −4 ). The distributions of the scored protein domains indicated that CBM588 had a considerably higher ( p < 10 −5 ) proportion of carbohydrate-binding modules than other bacteria, which suggested the superior ability of CBM588 to access carbohydrates as a metabolic driver to the bowel microbiome. These results demonstrated the use of integrated counts of protein domains as a feasible readout for metabolic potential within bacteria genomes and human metagenomes." @default.
• W2983669283 created "2019-11-22" @default.
• W2983669283 creator A5027746176 @default.
• W2983669283 creator A5029035458 @default.
• W2983669283 creator A5036428672 @default.
• W2983669283 creator A5058006370 @default.
• W2983669283 creator A5058408669 @default.
• W2983669283 creator A5059065946 @default.
• W2983669283 creator A5061402622 @default.
• W2983669283 creator A5088040773 @default.
• W2983669283 creator A5090292819 @default.
• W2983669283 date "2019-11-14" @default.
• W2983669283 modified "2023-10-18" @default.
• W2983669283 title "Integrated Counts of Carbohydrate-Active Protein Domains as Metabolic Readouts to Distinguish Probiotic Biology and Human Fecal Metagenomes" @default.
• W2983669283 cites W1507338356 @default.
• W2983669283 cites W1713943024 @default.
• W2983669283 cites W1965985248 @default.
• W2983669283 cites W1968198747 @default.
• W2983669283 cites W1985537916 @default.
• W2983669283 cites W1991842136 @default.
• W2983669283 cites W1995355078 @default.
• W2983669283 cites W2022825068 @default.
• W2983669283 cites W2034285706 @default.
• W2983669283 cites W2056941858 @default.
• W2983669283 cites W2060872094 @default.
• W2983669283 cites W2069689025 @default.
• W2983669283 cites W2070366335 @default.
• W2983669283 cites W2102746137 @default.
• W2983669283 cites W2103539617 @default.
• W2983669283 cites W2110300022 @default.
• W2983669283 cites W2120830211 @default.
• W2983669283 cites W2120878769 @default.
• W2983669283 cites W2120902911 @default.
• W2983669283 cites W2122559203 @default.
• W2983669283 cites W2124351063 @default.
• W2983669283 cites W2128711701 @default.
• W2983669283 cites W2138122982 @default.
• W2983669283 cites W2144680528 @default.
• W2983669283 cites W2149028378 @default.
• W2983669283 cites W2149824014 @default.
• W2983669283 cites W2150320991 @default.
• W2983669283 cites W2152872424 @default.
• W2983669283 cites W2160166285 @default.
• W2983669283 cites W2167692246 @default.
• W2983669283 cites W2170551349 @default.
• W2983669283 cites W2170925079 @default.
• W2983669283 cites W2173924792 @default.
• W2983669283 cites W2267159929 @default.
• W2983669283 cites W2555180552 @default.
• W2983669283 cites W2613127536 @default.
• W2983669283 cites W2747759105 @default.
• W2983669283 cites W2754071339 @default.
• W2983669283 cites W2754579667 @default.
• W2983669283 cites W2897611961 @default.
• W2983669283 cites W2916965512 @default.
• W2983669283 cites W4230770774 @default.
• W2983669283 cites W4294216483 @default.
• W2983669283 doi "https://doi.org/10.1038/s41598-019-53173-7" @default.
• W2983669283 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6856387" @default.
• W2983669283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31727954" @default.
• W2983669283 hasPublicationYear "2019" @default.
• W2983669283 type Work @default.
• W2983669283 sameAs 2983669283 @default.
• W2983669283 citedByCount "2" @default.
• W2983669283 countsByYear W29836692832020 @default.
• W2983669283 countsByYear W29836692832022 @default.
• W2983669283 crossrefType "journal-article" @default.
• W2983669283 hasAuthorship W2983669283A5027746176 @default.
• W2983669283 hasAuthorship W2983669283A5029035458 @default.
• W2983669283 hasAuthorship W2983669283A5036428672 @default.
• W2983669283 hasAuthorship W2983669283A5058006370 @default.
• W2983669283 hasAuthorship W2983669283A5058408669 @default.
• W2983669283 hasAuthorship W2983669283A5059065946 @default.
• W2983669283 hasAuthorship W2983669283A5061402622 @default.
• W2983669283 hasAuthorship W2983669283A5088040773 @default.
• W2983669283 hasAuthorship W2983669283A5090292819 @default.
• W2983669283 hasBestOaLocation W29836692831 @default.
• W2983669283 hasConcept C104317684 @default.
• W2983669283 hasConcept C108625454 @default.
• W2983669283 hasConcept C143121216 @default.
• W2983669283 hasConcept C15151743 @default.
• W2983669283 hasConcept C206212055 @default.
• W2983669283 hasConcept C2780255968 @default.
• W2983669283 hasConcept C31903555 @default.
• W2983669283 hasConcept C523546767 @default.
• W2983669283 hasConcept C54355233 @default.
• W2983669283 hasConcept C55493867 @default.
• W2983669283 hasConcept C60644358 @default.
• W2983669283 hasConcept C70721500 @default.
• W2983669283 hasConcept C86803240 @default.
• W2983669283 hasConcept C89423630 @default.
• W2983669283 hasConceptScore W2983669283C104317684 @default.
• W2983669283 hasConceptScore W2983669283C108625454 @default.
• W2983669283 hasConceptScore W2983669283C143121216 @default.
• W2983669283 hasConceptScore W2983669283C15151743 @default.
• W2983669283 hasConceptScore W2983669283C206212055 @default.
• W2983669283 hasConceptScore W2983669283C2780255968 @default.
• W2983669283 hasConceptScore W2983669283C31903555 @default.
• W2983669283 hasConceptScore W2983669283C523546767 @default.
• W2983669283 hasConceptScore W2983669283C54355233 @default.

• next