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- W2983742128 abstract "A new type aporphine-benzylisoquinoline alkaloid leptofumarine (1) was isolated from Leptopyrum fumarioides L. The structure of 1 was elucidated based on spectroscopic evidence. Leptofumarine together with the previously isolated leptopyrine (2) were evaluated for their effect on macrophages and bone marrow (BM) cells in vitro. Both alkaloids inhibited cytokine production by LPS-stimulated peritoneal macrophages. Leptopyrine suppressed osteoclast and osteoblast formation, while leptofumarine affected only osteoblastogenesis." @default.
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- W2983742128 date "2019-11-08" @default.
- W2983742128 modified "2023-10-14" @default.
- W2983742128 title "Alkaloids from the aerial parts of Leptopyrum fumarioides express immunomodulatory activity" @default.
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- W2983742128 doi "https://doi.org/10.1080/10286020.2019.1666821" @default.
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