FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2983811312> ?p ?o ?g. }

• W2983811312 endingPage "1423" @default.
• W2983811312 startingPage "1419" @default.
• W2983811312 abstract "Abstract Introduction The rate of nicotine metabolism, estimated by the nicotine metabolite ratio (NMR), is an important determinant of tobacco dependence. This study investigated the effect of NMR on smoking behavior due to nicotine reinforcement during ad libitum smoking. Aims and Methods As part of a larger study, participants were stratified based on saliva NMR as fast and slow metabolizers. After smoking a cigarette and measuring nicotine blood concentrations, participants smoked as desired over a 90-minute period. Analysis included time to first cigarette, total number of cigarettes, total number of puffs, and weight of tobacco consumed. Results Sixty-one (48%) participants were fast metabolizers and 66 (52%) slow metabolizers by NMR. No significant differences were found regarding the smoking topography variables by NMR. Normal metabolizers by genotype (n = 79) had a shorter time to first cigarette than reduced metabolizers (n = 39; p = .032). Blacks smoked fewer cigarettes (p = .008) and took fewer total puffs (p = .002) compared with Whites. Among Whites, fast metabolizers by NMR had a shorter time to first cigarette compared with slow metabolizers (p = .014). Among fast metabolizers, Whites had, compared with Blacks, shorter latency to first cigarette (p = .003) and higher number of total puffs (p = .014) and cigarettes smoked (p = .014). Baseline cigarettes per day and nicotine elimination half-life significantly predicted topography outcomes. Conclusions Saliva NMR did not predict cigarette reinforcement during a relatively brief period of ad libitum smoking. Differences were seen by race, with White fast metabolizers by NMR having shorter time to first cigarettes compared with slow metabolizers. Implications After a 90-minute period of nicotine abstinence, NMR was not significantly associated with smoking reinforcement. Slow and fast metabolizers had similar time to first cigarette, number of cigarettes smoked, total number of puffs, and tobacco consumed; however, within-race differences show that within Whites, fast metabolizers had a faster time to first cigarette than slow metabolizers." @default.
• W2983811312 created "2019-11-22" @default.
• W2983811312 creator A5012344139 @default.
• W2983811312 creator A5043384946 @default.
• W2983811312 creator A5065472330 @default.
• W2983811312 creator A5073258440 @default.
• W2983811312 creator A5083956843 @default.
• W2983811312 creator A5083971769 @default.
• W2983811312 date "2019-11-14" @default.
• W2983811312 modified "2023-10-17" @default.
• W2983811312 title "Effects of Nicotine Metabolic Rate on Cigarette Reinforcement" @default.
• W2983811312 cites W1983428212 @default.
• W2983811312 cites W1984116490 @default.
• W2983811312 cites W1993121994 @default.
• W2983811312 cites W2015234747 @default.
• W2983811312 cites W2021089766 @default.
• W2983811312 cites W2021130343 @default.
• W2983811312 cites W2030471578 @default.
• W2983811312 cites W2043177796 @default.
• W2983811312 cites W2091407825 @default.
• W2983811312 cites W2101566038 @default.
• W2983811312 cites W2120595117 @default.
• W2983811312 cites W2124496403 @default.
• W2983811312 cites W2136827296 @default.
• W2983811312 cites W2137599927 @default.
• W2983811312 cites W2153885478 @default.
• W2983811312 cites W2388180246 @default.
• W2983811312 cites W2389469497 @default.
• W2983811312 cites W2438200560 @default.
• W2983811312 cites W2511528498 @default.
• W2983811312 cites W2550204629 @default.
• W2983811312 cites W2774341657 @default.
• W2983811312 cites W2806596446 @default.
• W2983811312 cites W2890573975 @default.
• W2983811312 doi "https://doi.org/10.1093/ntr/ntz210" @default.
• W2983811312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7364822" @default.
• W2983811312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31725872" @default.
• W2983811312 hasPublicationYear "2019" @default.
• W2983811312 type Work @default.
• W2983811312 sameAs 2983811312 @default.
• W2983811312 citedByCount "2" @default.
• W2983811312 countsByYear W29838113122021 @default.
• W2983811312 countsByYear W29838113122023 @default.
• W2983811312 crossrefType "journal-article" @default.
• W2983811312 hasAuthorship W2983811312A5012344139 @default.
• W2983811312 hasAuthorship W2983811312A5043384946 @default.
• W2983811312 hasAuthorship W2983811312A5065472330 @default.
• W2983811312 hasAuthorship W2983811312A5073258440 @default.
• W2983811312 hasAuthorship W2983811312A5083956843 @default.
• W2983811312 hasAuthorship W2983811312A5083971769 @default.
• W2983811312 hasBestOaLocation W29838113122 @default.
• W2983811312 hasConcept C126322002 @default.
• W2983811312 hasConcept C142724271 @default.
• W2983811312 hasConcept C2776319443 @default.
• W2983811312 hasConcept C2777477808 @default.
• W2983811312 hasConcept C2777843972 @default.
• W2983811312 hasConcept C2778647338 @default.
• W2983811312 hasConcept C2779547902 @default.
• W2983811312 hasConcept C3019085024 @default.
• W2983811312 hasConcept C42407357 @default.
• W2983811312 hasConcept C504460877 @default.
• W2983811312 hasConcept C71924100 @default.
• W2983811312 hasConceptScore W2983811312C126322002 @default.
• W2983811312 hasConceptScore W2983811312C142724271 @default.
• W2983811312 hasConceptScore W2983811312C2776319443 @default.
• W2983811312 hasConceptScore W2983811312C2777477808 @default.
• W2983811312 hasConceptScore W2983811312C2777843972 @default.
• W2983811312 hasConceptScore W2983811312C2778647338 @default.
• W2983811312 hasConceptScore W2983811312C2779547902 @default.
• W2983811312 hasConceptScore W2983811312C3019085024 @default.
• W2983811312 hasConceptScore W2983811312C42407357 @default.
• W2983811312 hasConceptScore W2983811312C504460877 @default.
• W2983811312 hasConceptScore W2983811312C71924100 @default.
• W2983811312 hasFunder F4320320994 @default.
• W2983811312 hasFunder F4320334506 @default.
• W2983811312 hasFunder F4320337347 @default.
• W2983811312 hasFunder F4320337375 @default.
• W2983811312 hasIssue "8" @default.
• W2983811312 hasLocation W29838113121 @default.
• W2983811312 hasLocation W29838113122 @default.
• W2983811312 hasLocation W29838113123 @default.
• W2983811312 hasLocation W29838113124 @default.
• W2983811312 hasOpenAccess W2983811312 @default.
• W2983811312 hasPrimaryLocation W29838113121 @default.
• W2983811312 hasRelatedWork W196912332 @default.
• W2983811312 hasRelatedWork W1976559720 @default.
• W2983811312 hasRelatedWork W1991683131 @default.
• W2983811312 hasRelatedWork W2006420792 @default.
• W2983811312 hasRelatedWork W2012692477 @default.
• W2983811312 hasRelatedWork W2126278930 @default.
• W2983811312 hasRelatedWork W2466087406 @default.
• W2983811312 hasRelatedWork W280970742 @default.
• W2983811312 hasRelatedWork W4225001206 @default.
• W2983811312 hasRelatedWork W4247660328 @default.
• W2983811312 hasVolume "22" @default.
• W2983811312 isParatext "false" @default.
• W2983811312 isRetracted "false" @default.
• W2983811312 magId "2983811312" @default.

• next