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- W2983817848 abstract "Hemodilution is one of the sequelae of cardiopulmonary bypass (CPB). Autologous blood priming (retrograde autologous priming [RAP]/venous antegrade priming [VAP]) and acute normovolemic hemodilution (ANH) may be effective techniques to minimize hemodilution. The primary objective of this study is to investigate the impact of RAP/VAP combined with ANH on changes in cerebral saturations. A retrospective analysis of 52 patients undergoing congenital cardiac surgery requiring CPB between July 2014 and March 2015 was performed. Bivariate analysis correlated RAP/VAP and ANH volumes. S r O 2 change scores were regressed on all covariates using multivariable least-squares models. The average percent of circulating blood volume (CBV) removed during RAP/VAP was 21 ± 10% in the cyanotic group and 15 ± 5% in the acyanotic group ( p =.006). There was a decrease in S r O 2 from 70 ± 11% at baseline to 55 ± 13% at CPB initiation, although this decrease did not differ by cyanosis ( p = .668) or use of ANH ( p = .566). Bivariate correlation and multivariable regression analysis of the S r O 2 change score further demonstrated no statistically significant correlation between percent of CBV removed during RAP/VAP or ANH and the magnitude of the decline in S r O 2. RAP and VAP help minimize hemodilution at the onset of CPB. This study further supports the use of these techniques in a pediatric population by demonstrating declines in S r O 2 during RAP/VAP were consistent among cyanotic and acyanotic, including those who underwent ANH." @default.
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- W2983817848 date "2017-09-01" @default.
- W2983817848 modified "2023-10-18" @default.
- W2983817848 title "The Effect of Autologus Blood Priming on Cerebral Oximetry in Congenital Cardiac Surgery Patients" @default.
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- W2983817848 doi "https://doi.org/10.1051/ject/201749168" @default.
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