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• W2984138889 abstract "Organophosphorus insecticides (OPs) have been widely used to control agricultural pests, which has raised concerns about OP residues in crops and the environment. In this study, we investigated the degradation kinetics and pathways of 8 OPs by Cupriavidus nantongensis X1T and identified the enzyme via gene cloning and in vitro assays. The degradation half-life of methyl parathion, triazophos, and phoxim was only 5, 9, and 43 min, respectively. It was 46 fold faster than that of triazophos by Bacillus sp. TAP-1, a well-studied triazophos-degrader. Strain X1T completely degraded not only chlorpyrifos, methyl parathion, parathion, fenitrothion, triazophos, and phoxim at 50 mg/L within 48 h but also the phenolic metabolites. This was the fastest degradation of OPs by bacterial whole cells reported thus far. The OPs were first hydrolyzed by an OP hydrolase encoded by the opdB gene in strain X1T, followed by further degradation of the metabolites. The crude enzyme maintained a full activity." @default.
• W2984138889 created "2019-11-22" @default.
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• W2984138889 date "2019-11-18" @default.
• W2984138889 modified "2023-10-03" @default.
• W2984138889 title "Minute-Speed Biodegradation of Organophosphorus Insecticides by <i>Cupriavidus nantongensis</i> X1^T" @default.
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• W2984138889 doi "https://doi.org/10.1021/acs.jafc.9b06157" @default.
• W2984138889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31738544" @default.
• W2984138889 hasPublicationYear "2019" @default.
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