Matches in SemOpenAlex for { <https://semopenalex.org/work/W2984201747> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2984201747 abstract "The role of magnetism in the biological functioning of hemoglobin has been debated since its discovery by Pauling and Coryell in 1936. The hemoglobin molecule contains four heme groups each having a porphyrin layer with a Fe ion at the center. Here, we present combined density-functional theory and quantum Monte Carlo calculations for an effective model of Fe in a heme cluster. In comparison with these calculations, we analyze the experimental data on human adult hemoglobin (HbA) from the magnetic susceptibility, Mossbauer and magnetic circular dichroism (MCD) measurements. In both the deoxygenated (deoxy) and the oxygenated (oxy) cases, we show that local magnetic moments develop in the porphyrin layer with antiferromagnetic coupling to the Fe moment. Our calculations reproduce the magnetic susceptibility measurements on deoxy and oxy-HbA. For deoxy-HbA, we show that the anomalous MCD signal in the UV region is an experimental evidence for the presence of antiferromagnetic Fe-porphyrin correlations. The various important properties of hemoglobin are explained based on the antiferromagnetic correlations including the Bohr effect and cooperativity. This analysis shows that magnetism is involved in a fundamental way in the functioning of hemoglobin." @default.
- W2984201747 created "2019-11-22" @default.
- W2984201747 creator A5009927174 @default.
- W2984201747 creator A5015399650 @default.
- W2984201747 creator A5052121416 @default.
- W2984201747 creator A5084775651 @default.
- W2984201747 date "2019-11-13" @default.
- W2984201747 modified "2023-10-16" @default.
- W2984201747 title "Magnetic mechanism for the biological functioning of hemoglobin" @default.
- W2984201747 doi "https://doi.org/10.48550/arxiv.1911.05442" @default.
- W2984201747 hasPublicationYear "2019" @default.
- W2984201747 type Work @default.
- W2984201747 sameAs 2984201747 @default.
- W2984201747 citedByCount "0" @default.
- W2984201747 crossrefType "posted-content" @default.
- W2984201747 hasAuthorship W2984201747A5009927174 @default.
- W2984201747 hasAuthorship W2984201747A5015399650 @default.
- W2984201747 hasAuthorship W2984201747A5052121416 @default.
- W2984201747 hasAuthorship W2984201747A5084775651 @default.
- W2984201747 hasBestOaLocation W29842017471 @default.
- W2984201747 hasConcept C121332964 @default.
- W2984201747 hasConcept C147597530 @default.
- W2984201747 hasConcept C152365726 @default.
- W2984201747 hasConcept C155355069 @default.
- W2984201747 hasConcept C166014724 @default.
- W2984201747 hasConcept C181199279 @default.
- W2984201747 hasConcept C185592680 @default.
- W2984201747 hasConcept C197162081 @default.
- W2984201747 hasConcept C26873012 @default.
- W2984201747 hasConcept C2776217839 @default.
- W2984201747 hasConcept C2778917026 @default.
- W2984201747 hasConcept C46141821 @default.
- W2984201747 hasConcept C4839761 @default.
- W2984201747 hasConcept C54553102 @default.
- W2984201747 hasConcept C55493867 @default.
- W2984201747 hasConcept C62520636 @default.
- W2984201747 hasConcept C68563686 @default.
- W2984201747 hasConceptScore W2984201747C121332964 @default.
- W2984201747 hasConceptScore W2984201747C147597530 @default.
- W2984201747 hasConceptScore W2984201747C152365726 @default.
- W2984201747 hasConceptScore W2984201747C155355069 @default.
- W2984201747 hasConceptScore W2984201747C166014724 @default.
- W2984201747 hasConceptScore W2984201747C181199279 @default.
- W2984201747 hasConceptScore W2984201747C185592680 @default.
- W2984201747 hasConceptScore W2984201747C197162081 @default.
- W2984201747 hasConceptScore W2984201747C26873012 @default.
- W2984201747 hasConceptScore W2984201747C2776217839 @default.
- W2984201747 hasConceptScore W2984201747C2778917026 @default.
- W2984201747 hasConceptScore W2984201747C46141821 @default.
- W2984201747 hasConceptScore W2984201747C4839761 @default.
- W2984201747 hasConceptScore W2984201747C54553102 @default.
- W2984201747 hasConceptScore W2984201747C55493867 @default.
- W2984201747 hasConceptScore W2984201747C62520636 @default.
- W2984201747 hasConceptScore W2984201747C68563686 @default.
- W2984201747 hasLocation W29842017471 @default.
- W2984201747 hasLocation W29842017472 @default.
- W2984201747 hasOpenAccess W2984201747 @default.
- W2984201747 hasPrimaryLocation W29842017471 @default.
- W2984201747 hasRelatedWork W1483418176 @default.
- W2984201747 hasRelatedWork W1988260728 @default.
- W2984201747 hasRelatedWork W1997225306 @default.
- W2984201747 hasRelatedWork W2040677372 @default.
- W2984201747 hasRelatedWork W2067838687 @default.
- W2984201747 hasRelatedWork W2084989236 @default.
- W2984201747 hasRelatedWork W2164816742 @default.
- W2984201747 hasRelatedWork W2240352004 @default.
- W2984201747 hasRelatedWork W2377143193 @default.
- W2984201747 hasRelatedWork W3030400061 @default.
- W2984201747 isParatext "false" @default.
- W2984201747 isRetracted "false" @default.
- W2984201747 magId "2984201747" @default.
- W2984201747 workType "article" @default.