FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2984231566> ?p ?o ?g. }

• W2984231566 endingPage "115289" @default.
• W2984231566 startingPage "115289" @default.
• W2984231566 abstract "An environmental water sample fractionation framework was developed based on effects-directed analysis (EDA) to detect known and unknown compounds of concern in different waters. Secondary effluent from a wastewater treatment plant was used to demonstrate the effectiveness of the developed framework for characterizing estrogenic compounds in the effluent. The effluent was spiked with known estrogenic compounds to validate the framework in a targeted approach and an unspiked sample was also investigated in a non-targeted approach. The framework separated compounds based on polarity and adsorption using liquid-liquid extraction followed by solid phase extraction. The targeted and non-targeted effluents generated six fractions each, which were assessed for estrogenic activity using an in vitro bioassay (yeast estrogen screen - YES). Three out of the six fractions in each case, along with the raw effluent, showed estrogen equivalent concentrations (EEQs) ranging between 1.0 and 3.0 μg/L. Directed by the assay results, these estrogenic fractions were further analyzed using liquid- and gas-chromatography coupled with mass spectrometry for compound identification. The developed separation framework coupled with a bioassay aided in identification of both known and unknown compounds producing estrogenic effects in the water sample. The approach of fractionation followed by concentration helped isolate and elevate contaminant levels without necessarily concentrating potential matrix effects that could cause interfering cytotoxicity and inhibition in the bioassay. The targeted analysis showed consistency between predicted and observed results, while the non-targeted analysis revealed the presence of three estrogenic compounds in the unspiked effluent: di-isobutyl phthalate, diethyl phthalate and benzophenone, that were confirmed with standards. The study mainly aimed at development and validation of a simple yet effective EDA framework with low cost techniques for water and wastewater toxicity screening and evaluation, and the results suggested that the developed framework could be used as a screening tool for isolating and identifying unknown compounds in a complex water sample." @default.
• W2984231566 created "2019-11-22" @default.
• W2984231566 creator A5069180263 @default.
• W2984231566 creator A5070498910 @default.
• W2984231566 creator A5072236360 @default.
• W2984231566 creator A5088540454 @default.
• W2984231566 date "2020-03-01" @default.
• W2984231566 modified "2023-10-09" @default.
• W2984231566 title "Development of a separation framework for effects-based targeted and non-targeted toxicological screening of water and wastewater" @default.
• W2984231566 cites W1532654298 @default.
• W2984231566 cites W1966330849 @default.
• W2984231566 cites W1967060740 @default.
• W2984231566 cites W1967983823 @default.
• W2984231566 cites W1987846610 @default.
• W2984231566 cites W1989028887 @default.
• W2984231566 cites W1994701384 @default.
• W2984231566 cites W1999879476 @default.
• W2984231566 cites W2000551454 @default.
• W2984231566 cites W2001191441 @default.
• W2984231566 cites W2002058908 @default.
• W2984231566 cites W2005040871 @default.
• W2984231566 cites W2009314552 @default.
• W2984231566 cites W2014939665 @default.
• W2984231566 cites W2028666899 @default.
• W2984231566 cites W2040545202 @default.
• W2984231566 cites W2046991401 @default.
• W2984231566 cites W2051249897 @default.
• W2984231566 cites W2059133559 @default.
• W2984231566 cites W2060001766 @default.
• W2984231566 cites W2072714396 @default.
• W2984231566 cites W2074578678 @default.
• W2984231566 cites W2076519840 @default.
• W2984231566 cites W2078708930 @default.
• W2984231566 cites W2085721925 @default.
• W2984231566 cites W2086906253 @default.
• W2984231566 cites W2089017396 @default.
• W2984231566 cites W2090666484 @default.
• W2984231566 cites W2095718513 @default.
• W2984231566 cites W2103801051 @default.
• W2984231566 cites W2109879710 @default.
• W2984231566 cites W2122801439 @default.
• W2984231566 cites W2126328431 @default.
• W2984231566 cites W2131209943 @default.
• W2984231566 cites W2145907641 @default.
• W2984231566 cites W2146252001 @default.
• W2984231566 cites W2153479003 @default.
• W2984231566 cites W220035650 @default.
• W2984231566 cites W2232950086 @default.
• W2984231566 cites W2316101477 @default.
• W2984231566 cites W2344578960 @default.
• W2984231566 cites W2478099653 @default.
• W2984231566 cites W2556743218 @default.
• W2984231566 cites W2571099375 @default.
• W2984231566 cites W2593970154 @default.
• W2984231566 cites W2610919421 @default.
• W2984231566 cites W2611728245 @default.
• W2984231566 cites W2761476965 @default.
• W2984231566 cites W2767648609 @default.
• W2984231566 cites W2774382444 @default.
• W2984231566 cites W2778490246 @default.
• W2984231566 cites W2788898240 @default.
• W2984231566 cites W2807103424 @default.
• W2984231566 cites W2854479553 @default.
• W2984231566 cites W2888494973 @default.
• W2984231566 cites W2889044396 @default.
• W2984231566 doi "https://doi.org/10.1016/j.watres.2019.115289" @default.
• W2984231566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31785562" @default.
• W2984231566 hasPublicationYear "2020" @default.
• W2984231566 type Work @default.
• W2984231566 sameAs 2984231566 @default.
• W2984231566 citedByCount "11" @default.
• W2984231566 countsByYear W29842315662020 @default.
• W2984231566 countsByYear W29842315662021 @default.
• W2984231566 countsByYear W29842315662022 @default.
• W2984231566 countsByYear W29842315662023 @default.
• W2984231566 crossrefType "journal-article" @default.
• W2984231566 hasAuthorship W2984231566A5069180263 @default.
• W2984231566 hasAuthorship W2984231566A5070498910 @default.
• W2984231566 hasAuthorship W2984231566A5072236360 @default.
• W2984231566 hasAuthorship W2984231566A5088540454 @default.
• W2984231566 hasBestOaLocation W29842315661 @default.
• W2984231566 hasConcept C104488531 @default.
• W2984231566 hasConcept C107872376 @default.
• W2984231566 hasConcept C147455438 @default.
• W2984231566 hasConcept C185592680 @default.
• W2984231566 hasConcept C18903297 @default.
• W2984231566 hasConcept C2778576202 @default.
• W2984231566 hasConcept C39432304 @default.
• W2984231566 hasConcept C43617362 @default.
• W2984231566 hasConcept C4725764 @default.
• W2984231566 hasConcept C57442070 @default.
• W2984231566 hasConcept C81426234 @default.
• W2984231566 hasConcept C86803240 @default.
• W2984231566 hasConcept C87717796 @default.
• W2984231566 hasConcept C94061648 @default.
• W2984231566 hasConcept C97428945 @default.
• W2984231566 hasConceptScore W2984231566C104488531 @default.
• W2984231566 hasConceptScore W2984231566C107872376 @default.

• next