Matches in SemOpenAlex for { <https://semopenalex.org/work/W2984882013> ?p ?o ?g. }
- W2984882013 endingPage "103649" @default.
- W2984882013 startingPage "103649" @default.
- W2984882013 abstract "Abstract Angiotensin converting enzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) are important membrane peptidases. The inhibition of ACE and DPP-IV enzymes has become a key therapeutic target for the treatment of hypertension and diabetes. This study was conducted to discover membrane peptidase inhibitory peptides that inhibit ACE and DPP-IV. Egg proteins were cleaved by pepsin and trypsin in silico. The potential activity, solubility, absorption, distribution, metabolism, excretion, and toxicity of the peptides were then predicted online. Finally, ACE and DPP-IV were applied as molecular docking targets for the potential peptides. After simulating gastrointestinal digestion, the IC50 values of ADF, MIR, and FGR against ACE activity were 27.75 ± 0.90 mM, 24.97 ± 0.80 mM, and 66.98 ± 1.40 μM, against DPP-IV activity were 16.83 mM, 4.86 mM, and 46.22 mM, respectively. The ACE and DPP-IV inhibitory peptides identified from hen egg proteins can be used as functional food ingredients for controlling hypertension and diabetes." @default.
- W2984882013 created "2019-11-22" @default.
- W2984882013 creator A5032647921 @default.
- W2984882013 creator A5041470064 @default.
- W2984882013 creator A5058584688 @default.
- W2984882013 creator A5080853241 @default.
- W2984882013 creator A5090816464 @default.
- W2984882013 date "2020-01-01" @default.
- W2984882013 modified "2023-10-17" @default.
- W2984882013 title "Novel membrane peptidase inhibitory peptides with activity against angiotensin converting enzyme and dipeptidyl peptidase IV identified from hen eggs" @default.
- W2984882013 cites W114346019 @default.
- W2984882013 cites W1985306294 @default.
- W2984882013 cites W1988875831 @default.
- W2984882013 cites W2004469055 @default.
- W2984882013 cites W2007459036 @default.
- W2984882013 cites W2013106762 @default.
- W2984882013 cites W2026576068 @default.
- W2984882013 cites W2030485795 @default.
- W2984882013 cites W2049616145 @default.
- W2984882013 cites W2067916951 @default.
- W2984882013 cites W2081868797 @default.
- W2984882013 cites W2100944714 @default.
- W2984882013 cites W2118609667 @default.
- W2984882013 cites W2138216052 @default.
- W2984882013 cites W2191306565 @default.
- W2984882013 cites W2192648207 @default.
- W2984882013 cites W2203774030 @default.
- W2984882013 cites W2276283367 @default.
- W2984882013 cites W2344352760 @default.
- W2984882013 cites W2346184504 @default.
- W2984882013 cites W2507249427 @default.
- W2984882013 cites W2516118414 @default.
- W2984882013 cites W2560323685 @default.
- W2984882013 cites W2565296770 @default.
- W2984882013 cites W2593552230 @default.
- W2984882013 cites W2699544910 @default.
- W2984882013 cites W2728145659 @default.
- W2984882013 cites W2751236998 @default.
- W2984882013 cites W2762390540 @default.
- W2984882013 cites W2770814989 @default.
- W2984882013 cites W2773030076 @default.
- W2984882013 cites W2780363141 @default.
- W2984882013 cites W2782255984 @default.
- W2984882013 cites W2793492077 @default.
- W2984882013 cites W2885947383 @default.
- W2984882013 cites W2899607030 @default.
- W2984882013 cites W2947801270 @default.
- W2984882013 doi "https://doi.org/10.1016/j.jff.2019.103649" @default.
- W2984882013 hasPublicationYear "2020" @default.
- W2984882013 type Work @default.
- W2984882013 sameAs 2984882013 @default.
- W2984882013 citedByCount "44" @default.
- W2984882013 countsByYear W29848820132020 @default.
- W2984882013 countsByYear W29848820132021 @default.
- W2984882013 countsByYear W29848820132022 @default.
- W2984882013 countsByYear W29848820132023 @default.
- W2984882013 crossrefType "journal-article" @default.
- W2984882013 hasAuthorship W2984882013A5032647921 @default.
- W2984882013 hasAuthorship W2984882013A5041470064 @default.
- W2984882013 hasAuthorship W2984882013A5058584688 @default.
- W2984882013 hasAuthorship W2984882013A5080853241 @default.
- W2984882013 hasAuthorship W2984882013A5090816464 @default.
- W2984882013 hasBestOaLocation W29848820131 @default.
- W2984882013 hasConcept C134018914 @default.
- W2984882013 hasConcept C156490143 @default.
- W2984882013 hasConcept C17077164 @default.
- W2984882013 hasConcept C181199279 @default.
- W2984882013 hasConcept C185592680 @default.
- W2984882013 hasConcept C198710026 @default.
- W2984882013 hasConcept C27016395 @default.
- W2984882013 hasConcept C2777180221 @default.
- W2984882013 hasConcept C2781469919 @default.
- W2984882013 hasConcept C41625074 @default.
- W2984882013 hasConcept C55493867 @default.
- W2984882013 hasConcept C555293320 @default.
- W2984882013 hasConcept C84393581 @default.
- W2984882013 hasConcept C86803240 @default.
- W2984882013 hasConceptScore W2984882013C134018914 @default.
- W2984882013 hasConceptScore W2984882013C156490143 @default.
- W2984882013 hasConceptScore W2984882013C17077164 @default.
- W2984882013 hasConceptScore W2984882013C181199279 @default.
- W2984882013 hasConceptScore W2984882013C185592680 @default.
- W2984882013 hasConceptScore W2984882013C198710026 @default.
- W2984882013 hasConceptScore W2984882013C27016395 @default.
- W2984882013 hasConceptScore W2984882013C2777180221 @default.
- W2984882013 hasConceptScore W2984882013C2781469919 @default.
- W2984882013 hasConceptScore W2984882013C41625074 @default.
- W2984882013 hasConceptScore W2984882013C55493867 @default.
- W2984882013 hasConceptScore W2984882013C555293320 @default.
- W2984882013 hasConceptScore W2984882013C84393581 @default.
- W2984882013 hasConceptScore W2984882013C86803240 @default.
- W2984882013 hasFunder F4320335777 @default.
- W2984882013 hasLocation W29848820131 @default.
- W2984882013 hasOpenAccess W2984882013 @default.
- W2984882013 hasPrimaryLocation W29848820131 @default.
- W2984882013 hasRelatedWork W1948610151 @default.
- W2984882013 hasRelatedWork W1971767543 @default.
- W2984882013 hasRelatedWork W1983513268 @default.