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- W2984959219 abstract "Abstract Natural killer (NK) cells are cytotoxic lymphocytes targeting virus-infected cells and cancer cells. Specific pro- and antikilling signals modulate the overall ability of NK cells to kill cancer cells, however, several immune-escape mechanisms can be enacted by cancer cells to avoid NK-mediated killing. Recently, increasing evidence has shown that extracellular vesicles (EV) released by NK cells carry proteins and miRNAs able to exert an antitumoral effect, even within a highly immune-suppressive tumor microenvironment. These recent findings suggest a possible use of NK-derived EVs as anticancer agents and propel the development of new strategies to enrich EVs with the most effective anticancer cargo as a promising new anticancer approach." @default.
- W2984959219 created "2019-11-22" @default.
- W2984959219 creator A5012394561 @default.
- W2984959219 date "2020-01-01" @default.
- W2984959219 modified "2023-10-11" @default.
- W2984959219 title "Natural Killer Cell–Derived Vesicular miRNAs: A New Anticancer Approach?" @default.
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- W2984959219 doi "https://doi.org/10.1158/0008-5472.can-19-1450" @default.
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