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• W2985079637 abstract "Functional magnetic resonance imaging (fMRI) is widely used in clinical applications to highlight brain areas involved in specific cognitive processes. Brain impairments, such as tumors, suppress the fMRI activation of the anatomical areas they invade and, thus, brain-damaged functional networks present missing links/areas of activation. The identification of the missing circuitry components is of crucial importance to estimate the damage extent. The study of functional networks associated with clinical tasks but performed by healthy individuals becomes, therefore, of paramount concern. These healthy networks can, indeed, be used as control networks for clinical studies. In this work we investigate the functional architecture of 20 healthy individuals performing a language task designed for clinical purposes. We unveil a common architecture persistent across all subjects under study, that we call core network, which involves Broca's area, Wernicke's area, the premotor area, and the pre-supplementary motor area. We study the connectivity of this circuitry by using the k-core centrality measure, and we find that three of these areas belong to the most robust structure of the functional language network for the specific task under study. Our results provide useful insights on primarily important functional connections." @default.
• W2985079637 created "2019-11-22" @default.
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• W2985079637 date "2020-01-01" @default.
• W2985079637 modified "2023-10-16" @default.
• W2985079637 title "Core language brain network for fMRI language task used in clinical applications" @default.
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• W2985079637 doi "https://doi.org/10.1162/netn_a_00112" @default.
• W2985079637 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7006870" @default.
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• W2985079637 hasPublicationYear "2020" @default.
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