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- W2985964583 abstract "Objectives: Slow waves of intracranial pressure (ICP) are spontaneous oscillations with a frequency of 0.3–4 cycles/min. They are often associated with pathological conditions, following vasomotor activity in the cranial enclosure. This study quantifies the effects of general anaesthesia (GA) on the magnitude of B-waves compared with natural sleep and the conscious state. Materials and methods: Four groups of 30 patients each were formed to assess the magnitude of slow waves. Group A and group B consisted of normal pressure hydrocephalus (NPH) patients, each undergoing cerebrospinal fluid (CSF) infusion studies, conscious and under GA respectively. Group C comprised conscious, naturally asleep hydrocephalic patients undergoing overnight ICP monitoring; group D, which included deeply sedated head injury patients monitored in the intensive care unit (ICU), was compared with group C. Results: The average amplitude for group A patients was higher (0.23 ± 0.10 mmHg) than that of group B (0.15 ± 0.10 mmHg; p = 0.01). Overnight magnitude of slow waves was higher in group C (0.20 ± 0.13 mmHg) than in group D (0.11 ± 0.09 mmHg; p = 0.002). Conclusion: Slow waves of ICP are suppressed by GA and deep sedation. When using slow waves in clinical decision-making, it is important to consider the patients’ level of consciousness to avoid incorrect therapeutic and management decisions." @default.
- W2985964583 created "2019-11-22" @default.
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- W2985964583 date "2018-01-01" @default.
- W2985964583 modified "2023-10-14" @default.
- W2985964583 title "Are Slow Waves of Intracranial Pressure Suppressed by General Anaesthesia?" @default.
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- W2985964583 doi "https://doi.org/10.1007/978-3-319-65798-1_27" @default.
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