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• W2985965720 abstract "Background: Lactate dehydrogenase (LDH) is an easily accessible biological marker that has been associated with several pulmonary disorders. The aim of this study was to investigate the prognostic value of serum LDH in renal transplant recipients with severe community-acquired pneumonia (CAP). Methods: A total of 77 renal transplant recipients with severe CAP admitted to the intensive care unit (ICU) were screened for eligibility in this retrospective study. Patient characteristics and laboratory tests, such as LDH on day 1 (LDH day 1 ) and day 3 (LDH day 3 ) were recorded. Cox regression models were used to assess the performance of LDH to predict 90-day mortality. Results: Median LDH level was higher on day 1 in 90-day nonsurvivors (440 U/L, IQR, 362–1,055 U/L) than in survivors (334 U/L, IQR, 265–432 U/L; P day 1 (increase per 100 U/L), LDH day 3 (increase per 100 U/L) and LDH kinetics (increase per 10%) were independently associated with 90-day mortality. Conclusions: Serum LDH levels and LDH kinetics early were independently associated with 90-day mortality in renal transplant recipients with severe CAP. In future, the prognostic role of LDH needs to be warranted." @default.
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• W2985965720 date "2019-11-01" @default.
• W2985965720 modified "2023-10-01" @default.
• W2985965720 title "Lactate dehydrogenase as a prognostic marker of renal transplant recipients with severe community-acquired pneumonia: a 10-year retrospective study" @default.
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• W2985965720 doi "https://doi.org/10.21037/atm.2019.10.75" @default.
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