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- W2986114415 endingPage "134" @default.
- W2986114415 startingPage "111" @default.
- W2986114415 abstract "Angiogenesis plays a central role in human physiology from reproduction and fetal development to wound healing and tissue repair/regeneration. Clinically relevant therapies are needed for promoting angiogenesis in order to supply oxygen and nutrients after transplantation, thus relieving the symptoms of ischemia. Increase in angiogenesis can lead to the restoration of damaged tissues, thereby leading the way for successful tissue regeneration. Tissue regeneration is a broad field that has shown the convergence of various interdisciplinary fields, wherein living cells in conjugation with biomaterials have been tried and tested on to the human body. Although there is a prevalence of various approaches that hypothesize enhanced tissue regeneration via angiogenesis, none of them have been successful in gaining clinical relevance. Hence, the current review summarizes the recent cell-based and cell free (exosomes, extracellular vesicles, micro-RNAs) therapies, gene and biomaterial-based approaches that have been used for angiogenesis-mediated tissue regeneration and have been applied in treating disease models like ischemic heart, brain stroke, bone defects and corneal defects. This review also puts forward a concise report of the pre-clinical and clinical studies that have been performed so far; thereby presenting the credible impact of the development of biomaterials and their 3D concepts in the field of tissue engineering and regeneration, which would lead to the probable ways for heralding the successful future of angiogenesis-mediated approaches in the greater perspective of tissue engineering and regenerative medicine." @default.
- W2986114415 created "2019-11-22" @default.
- W2986114415 creator A5001804147 @default.
- W2986114415 creator A5013951741 @default.
- W2986114415 creator A5032982134 @default.
- W2986114415 creator A5041947896 @default.
- W2986114415 creator A5060947990 @default.
- W2986114415 date "2020-03-26" @default.
- W2986114415 modified "2023-10-14" @default.
- W2986114415 title "Recent Approaches for Angiogenesis in Search of Successful Tissue Engineering and Regeneration" @default.
- W2986114415 cites W1992112921 @default.
- W2986114415 cites W2055424631 @default.
- W2986114415 cites W2074196937 @default.
- W2986114415 cites W2152546971 @default.
- W2986114415 cites W2185926718 @default.
- W2986114415 cites W2284278240 @default.
- W2986114415 cites W2472451784 @default.
- W2986114415 cites W2514061078 @default.
- W2986114415 cites W2516605483 @default.
- W2986114415 cites W2517228411 @default.
- W2986114415 cites W2522345229 @default.
- W2986114415 cites W2558094665 @default.
- W2986114415 cites W2561023603 @default.
- W2986114415 cites W2563093790 @default.
- W2986114415 cites W2571952474 @default.
- W2986114415 cites W2574266062 @default.
- W2986114415 cites W2585886282 @default.
- W2986114415 cites W2587191473 @default.
- W2986114415 cites W2588210472 @default.
- W2986114415 cites W2588534180 @default.
- W2986114415 cites W2588790292 @default.
- W2986114415 cites W2592901756 @default.
- W2986114415 cites W2593657915 @default.
- W2986114415 cites W2595864505 @default.
- W2986114415 cites W2601082158 @default.
- W2986114415 cites W2603979534 @default.
- W2986114415 cites W2604208883 @default.
- W2986114415 cites W2604848293 @default.
- W2986114415 cites W2605245050 @default.
- W2986114415 cites W2606003725 @default.
- W2986114415 cites W2608549822 @default.
- W2986114415 cites W2609514370 @default.
- W2986114415 cites W2609961151 @default.
- W2986114415 cites W2611115211 @default.
- W2986114415 cites W2611211268 @default.
- W2986114415 cites W2613739181 @default.
- W2986114415 cites W2621337629 @default.
- W2986114415 cites W2622811561 @default.
- W2986114415 cites W2624864389 @default.
- W2986114415 cites W2625676117 @default.
- W2986114415 cites W2663229713 @default.
- W2986114415 cites W2673046167 @default.
- W2986114415 cites W2736311998 @default.
- W2986114415 cites W2737939816 @default.
- W2986114415 cites W2740529631 @default.
- W2986114415 cites W2740916176 @default.
- W2986114415 cites W2742236243 @default.
- W2986114415 cites W2743489607 @default.
- W2986114415 cites W2744119474 @default.
- W2986114415 cites W2744979016 @default.
- W2986114415 cites W2745014290 @default.
- W2986114415 cites W2747589912 @default.
- W2986114415 cites W2752617085 @default.
- W2986114415 cites W2755582093 @default.
- W2986114415 cites W2757568937 @default.
- W2986114415 cites W2761299005 @default.
- W2986114415 cites W2761425229 @default.
- W2986114415 cites W2762111176 @default.
- W2986114415 cites W2763392480 @default.
- W2986114415 cites W2763740968 @default.
- W2986114415 cites W2765425824 @default.
- W2986114415 cites W2765613340 @default.
- W2986114415 cites W2765999619 @default.
- W2986114415 cites W2766115418 @default.
- W2986114415 cites W2766272730 @default.
- W2986114415 cites W2766863719 @default.
- W2986114415 cites W2767223016 @default.
- W2986114415 cites W2767385783 @default.
- W2986114415 cites W2767421147 @default.
- W2986114415 cites W2769226496 @default.
- W2986114415 cites W2769468085 @default.
- W2986114415 cites W2770171434 @default.
- W2986114415 cites W2770270415 @default.
- W2986114415 cites W2771440768 @default.
- W2986114415 cites W2771830651 @default.
- W2986114415 cites W2772906938 @default.
- W2986114415 cites W2772945804 @default.
- W2986114415 cites W2773034849 @default.
- W2986114415 cites W2773261844 @default.
- W2986114415 cites W2774037381 @default.
- W2986114415 cites W2774221839 @default.
- W2986114415 cites W2778575740 @default.
- W2986114415 cites W2779482294 @default.
- W2986114415 cites W2782295751 @default.
- W2986114415 cites W2782303071 @default.
- W2986114415 cites W2782307234 @default.
- W2986114415 cites W2782639692 @default.
- W2986114415 cites W2782742524 @default.