Matches in SemOpenAlex for { <https://semopenalex.org/work/W2986229799> ?p ?o ?g. }
- W2986229799 endingPage "042054" @default.
- W2986229799 startingPage "042054" @default.
- W2986229799 abstract "Abstract We present here, the design and synthesis of a phenylbutyric acid-magnolol-coumarin conjugates (5). Compound 5 is a multifunctional molecule composed of magnolol, coumarin, phenylbutyric acid as model active drugs via ester. Upon entering tumor cells, ester bond cleavage occurs as well as active drug magnolol, coumarin and phenylbutyric acid release to attack cancer cells. In vitro anti-proliferation experiments showed that the inhibitory activity of compound 5 against HepG2, MCF-7, A431 and A549 cells was significantly higher than that of its single parent compound. Moreover, compound 5 had a long-term effect. Due to fluorescence of compound 5, it can serve as a fluorescence imaging agent and its uptake can be monitored. Compound 5 may provide a reference for the design of new derivatives of magnolol." @default.
- W2986229799 created "2019-11-22" @default.
- W2986229799 creator A5024595312 @default.
- W2986229799 creator A5027887669 @default.
- W2986229799 creator A5035654631 @default.
- W2986229799 creator A5054844187 @default.
- W2986229799 creator A5085276424 @default.
- W2986229799 date "2019-10-01" @default.
- W2986229799 modified "2023-09-26" @default.
- W2986229799 title "Magnolol–Coumarin–Phenylbutyric acid Conjugates: An Anticancer Prodrug via multiple targets" @default.
- W2986229799 cites W138746903 @default.
- W2986229799 cites W1740946044 @default.
- W2986229799 cites W1963618901 @default.
- W2986229799 cites W1970537994 @default.
- W2986229799 cites W1972881374 @default.
- W2986229799 cites W1979143271 @default.
- W2986229799 cites W1979649748 @default.
- W2986229799 cites W1980698726 @default.
- W2986229799 cites W1986613884 @default.
- W2986229799 cites W1986888271 @default.
- W2986229799 cites W1988441959 @default.
- W2986229799 cites W1995894933 @default.
- W2986229799 cites W1997129826 @default.
- W2986229799 cites W1997656535 @default.
- W2986229799 cites W1998048783 @default.
- W2986229799 cites W2003004088 @default.
- W2986229799 cites W2009702642 @default.
- W2986229799 cites W2021172314 @default.
- W2986229799 cites W2021358479 @default.
- W2986229799 cites W2023001077 @default.
- W2986229799 cites W2029612614 @default.
- W2986229799 cites W2030611702 @default.
- W2986229799 cites W2033131416 @default.
- W2986229799 cites W2042115382 @default.
- W2986229799 cites W2042817175 @default.
- W2986229799 cites W2066626576 @default.
- W2986229799 cites W2068751269 @default.
- W2986229799 cites W2069798828 @default.
- W2986229799 cites W2078996651 @default.
- W2986229799 cites W2087576960 @default.
- W2986229799 cites W2091659696 @default.
- W2986229799 cites W2094769960 @default.
- W2986229799 cites W2098585537 @default.
- W2986229799 cites W2108431862 @default.
- W2986229799 cites W2117442871 @default.
- W2986229799 cites W2170298919 @default.
- W2986229799 doi "https://doi.org/10.1088/1755-1315/330/4/042054" @default.
- W2986229799 hasPublicationYear "2019" @default.
- W2986229799 type Work @default.
- W2986229799 sameAs 2986229799 @default.
- W2986229799 citedByCount "2" @default.
- W2986229799 countsByYear W29862297992020 @default.
- W2986229799 countsByYear W29862297992023 @default.
- W2986229799 crossrefType "journal-article" @default.
- W2986229799 hasAuthorship W2986229799A5024595312 @default.
- W2986229799 hasAuthorship W2986229799A5027887669 @default.
- W2986229799 hasAuthorship W2986229799A5035654631 @default.
- W2986229799 hasAuthorship W2986229799A5054844187 @default.
- W2986229799 hasAuthorship W2986229799A5085276424 @default.
- W2986229799 hasBestOaLocation W29862297991 @default.
- W2986229799 hasConcept C108215921 @default.
- W2986229799 hasConcept C134306372 @default.
- W2986229799 hasConcept C178790620 @default.
- W2986229799 hasConcept C185592680 @default.
- W2986229799 hasConcept C197336794 @default.
- W2986229799 hasConcept C2781009524 @default.
- W2986229799 hasConcept C2781338262 @default.
- W2986229799 hasConcept C33923547 @default.
- W2986229799 hasConcept C43617362 @default.
- W2986229799 hasConcept C55493867 @default.
- W2986229799 hasConcept C71240020 @default.
- W2986229799 hasConcept C86803240 @default.
- W2986229799 hasConcept C98274493 @default.
- W2986229799 hasConceptScore W2986229799C108215921 @default.
- W2986229799 hasConceptScore W2986229799C134306372 @default.
- W2986229799 hasConceptScore W2986229799C178790620 @default.
- W2986229799 hasConceptScore W2986229799C185592680 @default.
- W2986229799 hasConceptScore W2986229799C197336794 @default.
- W2986229799 hasConceptScore W2986229799C2781009524 @default.
- W2986229799 hasConceptScore W2986229799C2781338262 @default.
- W2986229799 hasConceptScore W2986229799C33923547 @default.
- W2986229799 hasConceptScore W2986229799C43617362 @default.
- W2986229799 hasConceptScore W2986229799C55493867 @default.
- W2986229799 hasConceptScore W2986229799C71240020 @default.
- W2986229799 hasConceptScore W2986229799C86803240 @default.
- W2986229799 hasConceptScore W2986229799C98274493 @default.
- W2986229799 hasIssue "4" @default.
- W2986229799 hasLocation W29862297991 @default.
- W2986229799 hasOpenAccess W2986229799 @default.
- W2986229799 hasPrimaryLocation W29862297991 @default.
- W2986229799 hasRelatedWork W2072273640 @default.
- W2986229799 hasRelatedWork W2084267068 @default.
- W2986229799 hasRelatedWork W2401212985 @default.
- W2986229799 hasRelatedWork W2896328519 @default.
- W2986229799 hasRelatedWork W2949098585 @default.
- W2986229799 hasRelatedWork W2949137069 @default.
- W2986229799 hasRelatedWork W2949574874 @default.
- W2986229799 hasRelatedWork W2949948670 @default.