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• W2986401811 startingPage "117714" @default.
• W2986401811 abstract "A novel fluorescent biosensor based on dabcyl [(E)-4-((4-(dimethylamino) phenyl) diazenyl)benzoic acid] -modified anti-Mb aptamer (D-AMA) and 6-FAM(6-carboxyfluorescein) -modified complementary short chain (F-CSC)for the specific and sensitive detection of Mb levels is presented in this study. In PBS buffer solution, D-AMA bound to F-CSC, and then dabcyl quenched the fluorescence of 6-FAM. After adding Mb into the system, D-AMA bound to Mb and separated from F-CSC. The fluorescence of 6-FAM was restored after it separated from dabcyl. The assay exhibited high specificity and sensitivity toward Mb, with a low limit of detection of 0.07 ng/mL (S/N = 3) and linear relationships of 0.1–5 ng/mL. It was further applied to detect Mb levels in spiked human blood sera samples." @default.
• W2986401811 created "2019-11-22" @default.
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• W2986401811 date "2020-03-01" @default.
• W2986401811 modified "2023-10-09" @default.
• W2986401811 title "Fluorescent aptasensor based on D-AMA/F-CSC for the sensitive and specific recognition of myoglobin" @default.
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• W2986401811 doi "https://doi.org/10.1016/j.saa.2019.117714" @default.
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