Matches in SemOpenAlex for { <https://semopenalex.org/work/W2986480002> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2986480002 endingPage "1191" @default.
- W2986480002 startingPage "1182" @default.
- W2986480002 abstract "Background patellar tendinopathy is an overuse condition most commonly affecting jumping athletes. Surgery is reserved for refractory cases; however, it lacks high level clinical evidence and basic science to support its use. The purpose of this study was to determine the biomechanical and histological response of surgical excision on patellar tendinopathy in the rat collagenase tendinopathy model and correlate MRI findings. Methods Forty-eight Long Evans rats were divided into three groups: i) no patellar tendinopathy with surgical excision, ii) patella tendinopathy with surgical excision, and iii) patellar tendinopathy with no surgical excision. Endpoints included histology, mechanical testing, and MRI pre- and post-surgical intervention at one and four weeks. Results No difference in failure load or histological grading was seen between the groups at all time points. MRIs showed initial loss of tendon continuity followed by complete healing with elongated and thickened tendons in all groups. Conclusions While other research has reported immunohistochemistry and histology of collagenase-induced tendinopathy may be correlated with human pathogenesis, the novel MRI findings from our study suggest that the rat collagenase tendinopathy surgical model may be limited when extrapolating to humans. Further work is needed to determine if any correlation exists between the dosing, location, and animal effect of the collagenase injection model with MRI findings. This is needed before any collagenase model can be used to determine the effect of surgery in the pathogenic response to patella tendinopathy." @default.
- W2986480002 created "2019-11-22" @default.
- W2986480002 creator A5027493769 @default.
- W2986480002 creator A5028112833 @default.
- W2986480002 creator A5031229826 @default.
- W2986480002 creator A5040564275 @default.
- W2986480002 creator A5067651077 @default.
- W2986480002 creator A5070599159 @default.
- W2986480002 creator A5091135474 @default.
- W2986480002 date "2019-12-01" @default.
- W2986480002 modified "2023-10-16" @default.
- W2986480002 title "The effect of surgery on patellar tendinopathy: Novel use of MRI questions the exploitability of the rat collagenase model to humans" @default.
- W2986480002 cites W1822602594 @default.
- W2986480002 cites W1842770298 @default.
- W2986480002 cites W1963634867 @default.
- W2986480002 cites W1982300968 @default.
- W2986480002 cites W1995080334 @default.
- W2986480002 cites W2000189214 @default.
- W2986480002 cites W2018535224 @default.
- W2986480002 cites W2019579670 @default.
- W2986480002 cites W2020528616 @default.
- W2986480002 cites W2031295781 @default.
- W2986480002 cites W2051464884 @default.
- W2986480002 cites W2056034137 @default.
- W2986480002 cites W2065086852 @default.
- W2986480002 cites W2084653086 @default.
- W2986480002 cites W2113568840 @default.
- W2986480002 cites W2114853411 @default.
- W2986480002 cites W2119621864 @default.
- W2986480002 cites W2119632244 @default.
- W2986480002 cites W2162130278 @default.
- W2986480002 cites W2414759039 @default.
- W2986480002 cites W2514036669 @default.
- W2986480002 cites W2546365715 @default.
- W2986480002 cites W2606058663 @default.
- W2986480002 cites W4246350253 @default.
- W2986480002 doi "https://doi.org/10.1016/j.knee.2019.10.017" @default.
- W2986480002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31706694" @default.
- W2986480002 hasPublicationYear "2019" @default.
- W2986480002 type Work @default.
- W2986480002 sameAs 2986480002 @default.
- W2986480002 citedByCount "1" @default.
- W2986480002 countsByYear W29864800022020 @default.
- W2986480002 crossrefType "journal-article" @default.
- W2986480002 hasAuthorship W2986480002A5027493769 @default.
- W2986480002 hasAuthorship W2986480002A5028112833 @default.
- W2986480002 hasAuthorship W2986480002A5031229826 @default.
- W2986480002 hasAuthorship W2986480002A5040564275 @default.
- W2986480002 hasAuthorship W2986480002A5067651077 @default.
- W2986480002 hasAuthorship W2986480002A5070599159 @default.
- W2986480002 hasAuthorship W2986480002A5091135474 @default.
- W2986480002 hasConcept C141071460 @default.
- W2986480002 hasConcept C142724271 @default.
- W2986480002 hasConcept C181199279 @default.
- W2986480002 hasConcept C185592680 @default.
- W2986480002 hasConcept C2778394429 @default.
- W2986480002 hasConcept C2778911562 @default.
- W2986480002 hasConcept C2780105995 @default.
- W2986480002 hasConcept C2780368125 @default.
- W2986480002 hasConcept C2991944018 @default.
- W2986480002 hasConcept C55493867 @default.
- W2986480002 hasConcept C57742111 @default.
- W2986480002 hasConcept C71924100 @default.
- W2986480002 hasConceptScore W2986480002C141071460 @default.
- W2986480002 hasConceptScore W2986480002C142724271 @default.
- W2986480002 hasConceptScore W2986480002C181199279 @default.
- W2986480002 hasConceptScore W2986480002C185592680 @default.
- W2986480002 hasConceptScore W2986480002C2778394429 @default.
- W2986480002 hasConceptScore W2986480002C2778911562 @default.
- W2986480002 hasConceptScore W2986480002C2780105995 @default.
- W2986480002 hasConceptScore W2986480002C2780368125 @default.
- W2986480002 hasConceptScore W2986480002C2991944018 @default.
- W2986480002 hasConceptScore W2986480002C55493867 @default.
- W2986480002 hasConceptScore W2986480002C57742111 @default.
- W2986480002 hasConceptScore W2986480002C71924100 @default.
- W2986480002 hasIssue "6" @default.
- W2986480002 hasLocation W29864800021 @default.
- W2986480002 hasLocation W29864800022 @default.
- W2986480002 hasOpenAccess W2986480002 @default.
- W2986480002 hasPrimaryLocation W29864800021 @default.
- W2986480002 hasRelatedWork W1985611232 @default.
- W2986480002 hasRelatedWork W2119528520 @default.
- W2986480002 hasRelatedWork W2142313223 @default.
- W2986480002 hasRelatedWork W2883315895 @default.
- W2986480002 hasRelatedWork W2986480002 @default.
- W2986480002 hasRelatedWork W2999090650 @default.
- W2986480002 hasRelatedWork W3138435573 @default.
- W2986480002 hasRelatedWork W3192698230 @default.
- W2986480002 hasRelatedWork W4289917513 @default.
- W2986480002 hasRelatedWork W4303438853 @default.
- W2986480002 hasVolume "26" @default.
- W2986480002 isParatext "false" @default.
- W2986480002 isRetracted "false" @default.
- W2986480002 magId "2986480002" @default.
- W2986480002 workType "article" @default.