FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2986571569> ?p ?o ?g. }

• W2986571569 endingPage "e0224670" @default.
• W2986571569 startingPage "e0224670" @default.
• W2986571569 abstract "Research studies have demonstrated a reduction in the risk of mother-to-child transmission of HIV (MTCT) to less than 2%, or 5% in non-breastfeeding and breastfeeding populations, respectively, with antiretroviral interventions. However, the risk of MTCT in routine health-facility settings, where service delivery is usually sub-optimal needs monitoring.We conducted a retrospective review of data from 2008-2014, in two health facilities in Adamawa State, Nigeria. Descriptive statistics were used to estimate overall MTCT rate and MTCT rate by year, and period of prevention of mother-to-child transmission of HIV (PMTCT) protocol implementation. We conducted simple and multiple logistic-regression analyses, to identify predictors of MTCT.Data from 1,651 mother-to-infant pairs, with HIV deoxyribonucleic acid (DNA) polymerase-chain reaction (PCR) test results from 2008 (n = 49), 2009 (n = 246), 2010 (n = 280), 2011 (n = 335), 2012 (n = 290), 2013 (n = 225) and 2014 (n = 226) were analysed. The overall MTCT rate among HIV exposed infants (HEIs) was 9.7% (95% CI 8.3% - 11.1%) at a median age of 8 weeks (IQR = 6-20). The MTCT rate decreased from 14.3% (4.4%-24.2%) in 2008 to 4.9% (2.1%-7.7%) in 2014 (p = 0.016). The MTCT rate was the lowest (5.4% [3.7% - 7.0%]) when all pregnant women living with HIV received triple antiretroviral therapy, as treatment or prophylaxis (ARVT/P). Using the pooled data, we found that infant age, breastfeeding option, antiretroviral regimen and year were predictors of MTCT. The adjusted odds of MTCT were significantly higher, when neither mother nor HEI received ARVT/P (Adjusted odds ratio (AOR) 26.4 [14.0-49.8], and lower amongst infants born in 2012, compared with those born in 2008 (AOR 0.2 [0.0-1.0]).The MTCT rate declined significantly between 2008 and 2014 in these two routine health-facility settings in Nigeria. Our study suggests that ARVT/P yields the lowest MTCT. Thus, efforts to scale up lifelong ARVT/P (Option B+) in Nigeria should be accelerated." @default.
• W2986571569 created "2019-11-22" @default.
• W2986571569 creator A5009099235 @default.
• W2986571569 creator A5039431648 @default.
• W2986571569 creator A5091864164 @default.
• W2986571569 date "2019-11-11" @default.
• W2986571569 modified "2023-10-14" @default.
• W2986571569 title "Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria" @default.
• W2986571569 cites W1481636860 @default.
• W2986571569 cites W1530410272 @default.
• W2986571569 cites W1860696539 @default.
• W2986571569 cites W1892105775 @default.
• W2986571569 cites W1975160550 @default.
• W2986571569 cites W1989832259 @default.
• W2986571569 cites W2005251407 @default.
• W2986571569 cites W2027741016 @default.
• W2986571569 cites W2032782915 @default.
• W2986571569 cites W2053056658 @default.
• W2986571569 cites W2055522170 @default.
• W2986571569 cites W2060902722 @default.
• W2986571569 cites W2093783357 @default.
• W2986571569 cites W2113661592 @default.
• W2986571569 cites W2115826385 @default.
• W2986571569 cites W2125603054 @default.
• W2986571569 cites W2141862370 @default.
• W2986571569 cites W2146937158 @default.
• W2986571569 cites W2319272111 @default.
• W2986571569 cites W2461054226 @default.
• W2986571569 cites W2468225036 @default.
• W2986571569 cites W2521344231 @default.
• W2986571569 cites W2564732774 @default.
• W2986571569 cites W2892726287 @default.
• W2986571569 cites W2952263639 @default.
• W2986571569 doi "https://doi.org/10.1371/journal.pone.0224670" @default.
• W2986571569 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6844480" @default.
• W2986571569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31710613" @default.
• W2986571569 hasPublicationYear "2019" @default.
• W2986571569 type Work @default.
• W2986571569 sameAs 2986571569 @default.
• W2986571569 citedByCount "5" @default.
• W2986571569 countsByYear W29865715692019 @default.
• W2986571569 countsByYear W29865715692020 @default.
• W2986571569 countsByYear W29865715692022 @default.
• W2986571569 crossrefType "journal-article" @default.
• W2986571569 hasAuthorship W2986571569A5009099235 @default.
• W2986571569 hasAuthorship W2986571569A5039431648 @default.
• W2986571569 hasAuthorship W2986571569A5091864164 @default.
• W2986571569 hasBestOaLocation W29865715691 @default.
• W2986571569 hasConcept C118552586 @default.
• W2986571569 hasConcept C119599485 @default.
• W2986571569 hasConcept C126322002 @default.
• W2986571569 hasConcept C127413603 @default.
• W2986571569 hasConcept C131872663 @default.
• W2986571569 hasConcept C144024400 @default.
• W2986571569 hasConcept C149923435 @default.
• W2986571569 hasConcept C151956035 @default.
• W2986571569 hasConcept C187212893 @default.
• W2986571569 hasConcept C27415008 @default.
• W2986571569 hasConcept C2776283161 @default.
• W2986571569 hasConcept C2781413609 @default.
• W2986571569 hasConcept C3020294031 @default.
• W2986571569 hasConcept C71924100 @default.
• W2986571569 hasConcept C761482 @default.
• W2986571569 hasConcept C99454951 @default.
• W2986571569 hasConceptScore W2986571569C118552586 @default.
• W2986571569 hasConceptScore W2986571569C119599485 @default.
• W2986571569 hasConceptScore W2986571569C126322002 @default.
• W2986571569 hasConceptScore W2986571569C127413603 @default.
• W2986571569 hasConceptScore W2986571569C131872663 @default.
• W2986571569 hasConceptScore W2986571569C144024400 @default.
• W2986571569 hasConceptScore W2986571569C149923435 @default.
• W2986571569 hasConceptScore W2986571569C151956035 @default.
• W2986571569 hasConceptScore W2986571569C187212893 @default.
• W2986571569 hasConceptScore W2986571569C27415008 @default.
• W2986571569 hasConceptScore W2986571569C2776283161 @default.
• W2986571569 hasConceptScore W2986571569C2781413609 @default.
• W2986571569 hasConceptScore W2986571569C3020294031 @default.
• W2986571569 hasConceptScore W2986571569C71924100 @default.
• W2986571569 hasConceptScore W2986571569C761482 @default.
• W2986571569 hasConceptScore W2986571569C99454951 @default.
• W2986571569 hasIssue "11" @default.
• W2986571569 hasLocation W29865715691 @default.
• W2986571569 hasLocation W29865715692 @default.
• W2986571569 hasLocation W29865715693 @default.
• W2986571569 hasLocation W29865715694 @default.
• W2986571569 hasLocation W29865715695 @default.
• W2986571569 hasOpenAccess W2986571569 @default.
• W2986571569 hasPrimaryLocation W29865715691 @default.
• W2986571569 hasRelatedWork W1977498937 @default.
• W2986571569 hasRelatedWork W2054292852 @default.
• W2986571569 hasRelatedWork W2059020746 @default.
• W2986571569 hasRelatedWork W2116553858 @default.
• W2986571569 hasRelatedWork W2290757108 @default.
• W2986571569 hasRelatedWork W2313288316 @default.
• W2986571569 hasRelatedWork W2358966991 @default.
• W2986571569 hasRelatedWork W3214339505 @default.
• W2986571569 hasRelatedWork W72664801 @default.
• W2986571569 hasRelatedWork W2205928990 @default.

• next