Matches in SemOpenAlex for { <https://semopenalex.org/work/W2986720016> ?p ?o ?g. }
- W2986720016 endingPage "633" @default.
- W2986720016 startingPage "628" @default.
- W2986720016 abstract "B1 cells, which are distinct from conventional B cells, are a rare B lymphocyte subpopulation that plays a pivotal role in innate immunity. Extensive previous studies have revealed the functions and ontogeny of murine B1 cells, but the properties of human B1 cells have just begun to be uncovered over the past decade. The phenotype of human B1 cells has recently been proposed, facilitating further studies. Here, we review the latest knowledge on human B1 cells, especially their ontogeny. A previous study using xenotransplantation models showed that human hematopoietic stem cells (HSCs) derived from cord blood or adult bone marrow can produce B1 cells in vivo. A recent study by our group reported that human B1 cells in peripheral blood are derived from adult HSCs and persist for approximately 3 years in situ. These findings suggest that adult human HSCs have the ability to produce B1 cells and contribute to maintenance of the adult B1 cell pool in peripheral blood. Further understanding of human B1 cell functions and ontogeny may elucidate the pathogenesis of B cell malignancies and autoimmune diseases." @default.
- W2986720016 created "2019-11-22" @default.
- W2986720016 creator A5019930073 @default.
- W2986720016 creator A5060072613 @default.
- W2986720016 date "2019-11-12" @default.
- W2986720016 modified "2023-09-25" @default.
- W2986720016 title "Ontogeny of human B1 cells" @default.
- W2986720016 cites W183737772 @default.
- W2986720016 cites W1935631122 @default.
- W2986720016 cites W1946315708 @default.
- W2986720016 cites W1967102079 @default.
- W2986720016 cites W1971938738 @default.
- W2986720016 cites W1981003679 @default.
- W2986720016 cites W1992707199 @default.
- W2986720016 cites W2003955301 @default.
- W2986720016 cites W2008418299 @default.
- W2986720016 cites W2013369235 @default.
- W2986720016 cites W2021916493 @default.
- W2986720016 cites W2023502808 @default.
- W2986720016 cites W2024254647 @default.
- W2986720016 cites W2036862498 @default.
- W2986720016 cites W2040242408 @default.
- W2986720016 cites W2040576499 @default.
- W2986720016 cites W2044485561 @default.
- W2986720016 cites W2047346133 @default.
- W2986720016 cites W2049131071 @default.
- W2986720016 cites W2059383814 @default.
- W2986720016 cites W2063138712 @default.
- W2986720016 cites W2100582981 @default.
- W2986720016 cites W2103940281 @default.
- W2986720016 cites W2106545917 @default.
- W2986720016 cites W2106896872 @default.
- W2986720016 cites W2128587758 @default.
- W2986720016 cites W2137266284 @default.
- W2986720016 cites W2146764660 @default.
- W2986720016 cites W2160239136 @default.
- W2986720016 cites W2162395679 @default.
- W2986720016 cites W2208503742 @default.
- W2986720016 cites W2228241091 @default.
- W2986720016 cites W2510869140 @default.
- W2986720016 cites W2517782886 @default.
- W2986720016 cites W2521223951 @default.
- W2986720016 cites W2528397974 @default.
- W2986720016 cites W2543859185 @default.
- W2986720016 cites W2746147977 @default.
- W2986720016 cites W2924397209 @default.
- W2986720016 cites W2939168355 @default.
- W2986720016 cites W2940233936 @default.
- W2986720016 cites W2945191012 @default.
- W2986720016 doi "https://doi.org/10.1007/s12185-019-02775-y" @default.
- W2986720016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31721035" @default.
- W2986720016 hasPublicationYear "2019" @default.
- W2986720016 type Work @default.
- W2986720016 sameAs 2986720016 @default.
- W2986720016 citedByCount "16" @default.
- W2986720016 countsByYear W29867200162020 @default.
- W2986720016 countsByYear W29867200162021 @default.
- W2986720016 countsByYear W29867200162022 @default.
- W2986720016 countsByYear W29867200162023 @default.
- W2986720016 crossrefType "journal-article" @default.
- W2986720016 hasAuthorship W2986720016A5019930073 @default.
- W2986720016 hasAuthorship W2986720016A5060072613 @default.
- W2986720016 hasBestOaLocation W29867200161 @default.
- W2986720016 hasConcept C109159458 @default.
- W2986720016 hasConcept C126322002 @default.
- W2986720016 hasConcept C134018914 @default.
- W2986720016 hasConcept C203014093 @default.
- W2986720016 hasConcept C2778442404 @default.
- W2986720016 hasConcept C2780914630 @default.
- W2986720016 hasConcept C28328180 @default.
- W2986720016 hasConcept C2911091166 @default.
- W2986720016 hasConcept C37291498 @default.
- W2986720016 hasConcept C71924100 @default.
- W2986720016 hasConcept C86803240 @default.
- W2986720016 hasConcept C95444343 @default.
- W2986720016 hasConceptScore W2986720016C109159458 @default.
- W2986720016 hasConceptScore W2986720016C126322002 @default.
- W2986720016 hasConceptScore W2986720016C134018914 @default.
- W2986720016 hasConceptScore W2986720016C203014093 @default.
- W2986720016 hasConceptScore W2986720016C2778442404 @default.
- W2986720016 hasConceptScore W2986720016C2780914630 @default.
- W2986720016 hasConceptScore W2986720016C28328180 @default.
- W2986720016 hasConceptScore W2986720016C2911091166 @default.
- W2986720016 hasConceptScore W2986720016C37291498 @default.
- W2986720016 hasConceptScore W2986720016C71924100 @default.
- W2986720016 hasConceptScore W2986720016C86803240 @default.
- W2986720016 hasConceptScore W2986720016C95444343 @default.
- W2986720016 hasFunder F4320334764 @default.
- W2986720016 hasIssue "5" @default.
- W2986720016 hasLocation W29867200161 @default.
- W2986720016 hasLocation W29867200162 @default.
- W2986720016 hasOpenAccess W2986720016 @default.
- W2986720016 hasPrimaryLocation W29867200161 @default.
- W2986720016 hasRelatedWork W1569098572 @default.
- W2986720016 hasRelatedWork W2033885445 @default.
- W2986720016 hasRelatedWork W2062256187 @default.
- W2986720016 hasRelatedWork W2120223845 @default.
- W2986720016 hasRelatedWork W2386230525 @default.