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- W2987475329 abstract "Abstract This chapter aims to define biomarkers and surrogate endpoints and how they can be used to monitor kidney transplant recipients. The advent of new high-throughput technologies such as genomics and mass spectrometry has provided us access to a large array of new biological characteristics with the potential to predict clinical outcomes, pathological processes, and/or responses to therapy. While many of these new assays require ongoing validation in clinical trials before their utility has been confirmed, they do provide an opportunity to expand the number of diagnostic tools that will better stratify patients according to risk. It is envisaged that biomarkers and surrogate endpoints will be essential components in newly designed clinical trials. Biomarkers that stratify patients according to risk of an event or are predictive of a pathological process are described in detail. Surrogate endpoints that provide early prediction of graft or patient outcome as well as predicting the effect of treatment are also outlined." @default.
- W2987475329 created "2019-11-22" @default.
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- W2987475329 creator A5081669847 @default.
- W2987475329 date "2019-01-01" @default.
- W2987475329 modified "2023-09-30" @default.
- W2987475329 title "Biomarkers of Kidney Injury and Rejection" @default.
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