Matches in SemOpenAlex for { <https://semopenalex.org/work/W2987707890> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2987707890 endingPage "312" @default.
- W2987707890 startingPage "306" @default.
- W2987707890 abstract "To quantify the availability of authorised, age-appropriate paediatric medicines in clinical practice in the Netherlands and to identify gaps by assessing dispensing practice in a paediatric hospital.The availability of age-appropriate formulations was assessed by conducting a survey on the use of pharmacy compounded medicines among the paediatric hospitals in the Netherlands, and by analysing dispensing data of oral medication from the inpatient pharmacy of the largest paediatric hospital in the Netherlands. The age-appropriateness of the dispensed formulations was assessed on two aspects: dose-capability and acceptability. Liquid drug products that are unsuitable due to the presence of potentially harmful excipients, were identified based on the dosage in clinical practice.For 129 out of 139 drug substances included in the survey (93%), at least one of the eight respondents stated to use a pharmacy compounded product to meet the needs of their paediatric patients. The age-appropriateness of medicines dispensed from the inpatient pharmacy increased with age, and was higher for non-intensive care unit (ICU) patients than for ICU patients. We identified 15 drug products causing excipient exposure above the European Medicines Agency-recommended values.This study confirms there is still a large need for age-appropriate formulations in daily clinical practice. Pharmacy compounding for paediatric patients remains essential for many indications. The need for potentially harmful excipients in compounded products should be critically assessed." @default.
- W2987707890 created "2019-11-22" @default.
- W2987707890 creator A5016982472 @default.
- W2987707890 creator A5051627301 @default.
- W2987707890 creator A5059036704 @default.
- W2987707890 creator A5070631704 @default.
- W2987707890 creator A5084306784 @default.
- W2987707890 creator A5087424653 @default.
- W2987707890 date "2019-11-11" @default.
- W2987707890 modified "2023-09-27" @default.
- W2987707890 title "Availability of age-appropriate paediatric formulations in the Netherlands: the need in daily clinical practice remains" @default.
- W2987707890 cites W1808883145 @default.
- W2987707890 cites W1985701908 @default.
- W2987707890 cites W1986673622 @default.
- W2987707890 cites W2015191233 @default.
- W2987707890 cites W2034273601 @default.
- W2987707890 cites W2045374657 @default.
- W2987707890 cites W2047752822 @default.
- W2987707890 cites W2059907227 @default.
- W2987707890 cites W2141307228 @default.
- W2987707890 cites W2303291752 @default.
- W2987707890 cites W2539879719 @default.
- W2987707890 cites W2563046258 @default.
- W2987707890 cites W2735321973 @default.
- W2987707890 cites W2766743373 @default.
- W2987707890 doi "https://doi.org/10.1136/ejhpharm-2019-001977" @default.
- W2987707890 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8552141" @default.
- W2987707890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34697046" @default.
- W2987707890 hasPublicationYear "2019" @default.
- W2987707890 type Work @default.
- W2987707890 sameAs 2987707890 @default.
- W2987707890 citedByCount "6" @default.
- W2987707890 countsByYear W29877078902021 @default.
- W2987707890 countsByYear W29877078902022 @default.
- W2987707890 countsByYear W29877078902023 @default.
- W2987707890 crossrefType "journal-article" @default.
- W2987707890 hasAuthorship W2987707890A5016982472 @default.
- W2987707890 hasAuthorship W2987707890A5051627301 @default.
- W2987707890 hasAuthorship W2987707890A5059036704 @default.
- W2987707890 hasAuthorship W2987707890A5070631704 @default.
- W2987707890 hasAuthorship W2987707890A5084306784 @default.
- W2987707890 hasAuthorship W2987707890A5087424653 @default.
- W2987707890 hasBestOaLocation W29877078901 @default.
- W2987707890 hasConcept C10446079 @default.
- W2987707890 hasConcept C104863432 @default.
- W2987707890 hasConcept C159110408 @default.
- W2987707890 hasConcept C177713679 @default.
- W2987707890 hasConcept C190857496 @default.
- W2987707890 hasConcept C194828623 @default.
- W2987707890 hasConcept C207673951 @default.
- W2987707890 hasConcept C2426938 @default.
- W2987707890 hasConcept C2777436895 @default.
- W2987707890 hasConcept C2779974597 @default.
- W2987707890 hasConcept C512399662 @default.
- W2987707890 hasConcept C71924100 @default.
- W2987707890 hasConceptScore W2987707890C10446079 @default.
- W2987707890 hasConceptScore W2987707890C104863432 @default.
- W2987707890 hasConceptScore W2987707890C159110408 @default.
- W2987707890 hasConceptScore W2987707890C177713679 @default.
- W2987707890 hasConceptScore W2987707890C190857496 @default.
- W2987707890 hasConceptScore W2987707890C194828623 @default.
- W2987707890 hasConceptScore W2987707890C207673951 @default.
- W2987707890 hasConceptScore W2987707890C2426938 @default.
- W2987707890 hasConceptScore W2987707890C2777436895 @default.
- W2987707890 hasConceptScore W2987707890C2779974597 @default.
- W2987707890 hasConceptScore W2987707890C512399662 @default.
- W2987707890 hasConceptScore W2987707890C71924100 @default.
- W2987707890 hasIssue "6" @default.
- W2987707890 hasLocation W29877078901 @default.
- W2987707890 hasLocation W29877078902 @default.
- W2987707890 hasLocation W29877078903 @default.
- W2987707890 hasLocation W29877078904 @default.
- W2987707890 hasLocation W29877078905 @default.
- W2987707890 hasLocation W29877078906 @default.
- W2987707890 hasLocation W29877078907 @default.
- W2987707890 hasLocation W29877078908 @default.
- W2987707890 hasOpenAccess W2987707890 @default.
- W2987707890 hasPrimaryLocation W29877078901 @default.
- W2987707890 hasRelatedWork W2002144859 @default.
- W2987707890 hasRelatedWork W2055128302 @default.
- W2987707890 hasRelatedWork W2118396791 @default.
- W2987707890 hasRelatedWork W2260182467 @default.
- W2987707890 hasRelatedWork W2352573899 @default.
- W2987707890 hasRelatedWork W2353133219 @default.
- W2987707890 hasRelatedWork W2802859181 @default.
- W2987707890 hasRelatedWork W3188803873 @default.
- W2987707890 hasRelatedWork W2949077388 @default.
- W2987707890 hasRelatedWork W81195767 @default.
- W2987707890 hasVolume "28" @default.
- W2987707890 isParatext "false" @default.
- W2987707890 isRetracted "false" @default.
- W2987707890 magId "2987707890" @default.
- W2987707890 workType "article" @default.