FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2988409416> ?p ?o ?g. }

• W2988409416 endingPage "437" @default.
• W2988409416 startingPage "421" @default.
• W2988409416 abstract "Abstract Recent studies in mice reveal widespread cortical signals during task performance; however, the various task-related and task-independent processes underlying this activity are incompletely understood. Here, we recorded wide-field neural activity, as revealed by GCaMP6s, from dorsal cortex while simultaneously monitoring orofacial movements, walking, and arousal (pupil diameter) of head-fixed mice performing a Go/NoGo visual detection task and examined the ability of task performance and spontaneous or task-related movements to predict cortical activity. A linear model was able to explain a significant fraction (33–55% of variance) of widefield dorsal cortical activity, with the largest factors being movements (facial, walk, eye), response choice (hit, miss, false alarm), and arousal and indicate that a significant fraction of trial-to-trial variability arises from both spontaneous and task-related changes in state (e.g., movements, arousal). Importantly, secondary motor cortex was highly correlated with lick rate, critical for optimal task performance (high d′), and was the first region to significantly predict the lick response on target trials. These findings suggest that secondary motor cortex is critically involved in the decision and performance of learned movements and indicate that a significant fraction of trial-to-trial variation in cortical activity results from spontaneous and task-related movements and variations in behavioral/arousal state." @default.
• W2988409416 created "2019-11-22" @default.
• W2988409416 creator A5005698274 @default.
• W2988409416 creator A5071223228 @default.
• W2988409416 creator A5085964206 @default.
• W2988409416 creator A5088117570 @default.
• W2988409416 date "2019-11-11" @default.
• W2988409416 modified "2023-10-15" @default.
• W2988409416 title "Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task" @default.
• W2988409416 cites W1480668978 @default.
• W2988409416 cites W1519578210 @default.
• W2988409416 cites W1603077448 @default.
• W2988409416 cites W1906118549 @default.
• W2988409416 cites W1968019923 @default.
• W2988409416 cites W1970177188 @default.
• W2988409416 cites W1970585834 @default.
• W2988409416 cites W1971638449 @default.
• W2988409416 cites W1972869628 @default.
• W2988409416 cites W1975032719 @default.
• W2988409416 cites W1975389666 @default.
• W2988409416 cites W1988357356 @default.
• W2988409416 cites W1992910467 @default.
• W2988409416 cites W1996889564 @default.
• W2988409416 cites W2000083479 @default.
• W2988409416 cites W2002325846 @default.
• W2988409416 cites W2002667643 @default.
• W2988409416 cites W2005392553 @default.
• W2988409416 cites W2008372697 @default.
• W2988409416 cites W2028311911 @default.
• W2988409416 cites W2032838376 @default.
• W2988409416 cites W2040707073 @default.
• W2988409416 cites W2041812578 @default.
• W2988409416 cites W2042662796 @default.
• W2988409416 cites W2053790717 @default.
• W2988409416 cites W2059746123 @default.
• W2988409416 cites W2075073129 @default.
• W2988409416 cites W2081432059 @default.
• W2988409416 cites W2083803136 @default.
• W2988409416 cites W2084770399 @default.
• W2988409416 cites W2090094004 @default.
• W2988409416 cites W2098580305 @default.
• W2988409416 cites W2099401565 @default.
• W2988409416 cites W2100212553 @default.
• W2988409416 cites W2116679324 @default.
• W2988409416 cites W2138790588 @default.
• W2988409416 cites W2150951291 @default.
• W2988409416 cites W2180251131 @default.
• W2988409416 cites W2266164565 @default.
• W2988409416 cites W2280009513 @default.
• W2988409416 cites W2336155947 @default.
• W2988409416 cites W2336598759 @default.
• W2988409416 cites W2482462198 @default.
• W2988409416 cites W2513047215 @default.
• W2988409416 cites W2517512733 @default.
• W2988409416 cites W2551360963 @default.
• W2988409416 cites W2558181418 @default.
• W2988409416 cites W2567727905 @default.
• W2988409416 cites W2614257994 @default.
• W2988409416 cites W2616012590 @default.
• W2988409416 cites W2616734028 @default.
• W2988409416 cites W2794779684 @default.
• W2988409416 cites W2807415912 @default.
• W2988409416 cites W2880814084 @default.
• W2988409416 cites W2898208057 @default.
• W2988409416 cites W2909777960 @default.
• W2988409416 cites W2912119762 @default.
• W2988409416 cites W2937274403 @default.
• W2988409416 cites W2949634824 @default.
• W2988409416 cites W2952059832 @default.
• W2988409416 cites W2971688013 @default.
• W2988409416 cites W2982202918 @default.
• W2988409416 cites W4248532482 @default.
• W2988409416 doi "https://doi.org/10.1093/cercor/bhz206" @default.
• W2988409416 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7029483" @default.
• W2988409416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31711133" @default.
• W2988409416 hasPublicationYear "2019" @default.
• W2988409416 type Work @default.
• W2988409416 sameAs 2988409416 @default.
• W2988409416 citedByCount "112" @default.
• W2988409416 countsByYear W29884094162018 @default.
• W2988409416 countsByYear W29884094162019 @default.
• W2988409416 countsByYear W29884094162020 @default.
• W2988409416 countsByYear W29884094162021 @default.
• W2988409416 countsByYear W29884094162022 @default.
• W2988409416 countsByYear W29884094162023 @default.
• W2988409416 crossrefType "journal-article" @default.
• W2988409416 hasAuthorship W2988409416A5005698274 @default.
• W2988409416 hasAuthorship W2988409416A5071223228 @default.
• W2988409416 hasAuthorship W2988409416A5085964206 @default.
• W2988409416 hasAuthorship W2988409416A5088117570 @default.
• W2988409416 hasBestOaLocation W29884094161 @default.
• W2988409416 hasConcept C120843803 @default.
• W2988409416 hasConcept C153050134 @default.
• W2988409416 hasConcept C15744967 @default.
• W2988409416 hasConcept C162324750 @default.
• W2988409416 hasConcept C169760540 @default.
• W2988409416 hasConcept C180747234 @default.
• W2988409416 hasConcept C187736073 @default.

• next