Matches in SemOpenAlex for { <https://semopenalex.org/work/W2988447889> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2988447889 abstract "Neonatal sepsis is a life-threatening disorder among infants, which is associated with high morbidity and mortality. In recent years, although the management of newborns has improved, early diagnosis and treatment of neonatal early-onset sepsis (NEOS) are the major challenges for neonatologists in Neonatal intensive care units (NICUs). We assessed the diagnostic value of interleukins-35 (IL-35) in diagnosis of NEOS. A prospective process evaluation study was carried out in the NICU of Akbar-Abadi and Ali-Asghar Hospitals affiliated to Iran University of Medical Sciences from 2017 to 2018. Eighty hospitalized neonates with clinical suspicion of sepsis in the first 72 h of life entered the study by convenience or accidental sampling. Routine hematology tests regarding sepsis diagnosis were performed after admission. All subjects were assigned into two groups: newborns with proven sepsis and newborns with suspected sepsis. IL-35 levels in septic and unlikely infected hospitalized newborns were measured using Elisa Kit (ZellBio GmbH. Cat. No; ZB-10042C-H9648, Human Interleukin 35), and the results were compared. The mean IL-35 in serum samples from septic neonates was significantly higher than this variable in samples from unlikely infected newborns (13.41 ± 2.4 vs. 9.02 ± 2.6 pg/ml; p < 0.0001). The area under receiver-operating characteristic (ROC) curve for IL-35 was 0.895 (CI 95% = 0.826–0.963; p = 0.0001). The result of study showed serum IL-35 had a moderate accuracy (AUC = 0.895) for the diagnosis of NS. Therefore, serum IL-35 could be suggested as a predictive biomarker in neonatal early-onset sepsis. Further studies with larger sample size are strongly suggested." @default.
- W2988447889 created "2019-11-22" @default.
- W2988447889 creator A5000500025 @default.
- W2988447889 creator A5001285693 @default.
- W2988447889 creator A5003637481 @default.
- W2988447889 creator A5018361101 @default.
- W2988447889 creator A5025600160 @default.
- W2988447889 creator A5072283216 @default.
- W2988447889 date "2019-11-12" @default.
- W2988447889 modified "2023-09-25" @default.
- W2988447889 title "Assessment of serum interleukin-35 as a diagnostic biomarker of neonatal early-onset sepsis" @default.
- W2988447889 cites W1436265407 @default.
- W2988447889 cites W1970974623 @default.
- W2988447889 cites W1981400021 @default.
- W2988447889 cites W2019617588 @default.
- W2988447889 cites W2074045174 @default.
- W2988447889 cites W2085115798 @default.
- W2988447889 cites W2119347566 @default.
- W2988447889 cites W2134575990 @default.
- W2988447889 cites W2149532013 @default.
- W2988447889 cites W2167696296 @default.
- W2988447889 cites W2509784745 @default.
- W2988447889 cites W2522382625 @default.
- W2988447889 cites W2523676051 @default.
- W2988447889 cites W2737177296 @default.
- W2988447889 cites W2775759926 @default.
- W2988447889 cites W2797738061 @default.
- W2988447889 cites W2801761673 @default.
- W2988447889 cites W2807715149 @default.
- W2988447889 cites W2811261014 @default.
- W2988447889 cites W2884716143 @default.
- W2988447889 cites W2890730804 @default.
- W2988447889 cites W2892141352 @default.
- W2988447889 cites W2892268959 @default.
- W2988447889 cites W2893802903 @default.
- W2988447889 doi "https://doi.org/10.1007/s42452-019-1565-2" @default.
- W2988447889 hasPublicationYear "2019" @default.
- W2988447889 type Work @default.
- W2988447889 sameAs 2988447889 @default.
- W2988447889 citedByCount "1" @default.
- W2988447889 countsByYear W29884478892022 @default.
- W2988447889 crossrefType "journal-article" @default.
- W2988447889 hasAuthorship W2988447889A5000500025 @default.
- W2988447889 hasAuthorship W2988447889A5001285693 @default.
- W2988447889 hasAuthorship W2988447889A5003637481 @default.
- W2988447889 hasAuthorship W2988447889A5018361101 @default.
- W2988447889 hasAuthorship W2988447889A5025600160 @default.
- W2988447889 hasAuthorship W2988447889A5072283216 @default.
- W2988447889 hasBestOaLocation W29884478891 @default.
- W2988447889 hasConcept C203014093 @default.
- W2988447889 hasConcept C2775953899 @default.
- W2988447889 hasConcept C2778384902 @default.
- W2988447889 hasConcept C2781197716 @default.
- W2988447889 hasConcept C55493867 @default.
- W2988447889 hasConcept C71924100 @default.
- W2988447889 hasConcept C86803240 @default.
- W2988447889 hasConceptScore W2988447889C203014093 @default.
- W2988447889 hasConceptScore W2988447889C2775953899 @default.
- W2988447889 hasConceptScore W2988447889C2778384902 @default.
- W2988447889 hasConceptScore W2988447889C2781197716 @default.
- W2988447889 hasConceptScore W2988447889C55493867 @default.
- W2988447889 hasConceptScore W2988447889C71924100 @default.
- W2988447889 hasConceptScore W2988447889C86803240 @default.
- W2988447889 hasIssue "12" @default.
- W2988447889 hasLocation W29884478891 @default.
- W2988447889 hasOpenAccess W2988447889 @default.
- W2988447889 hasPrimaryLocation W29884478891 @default.
- W2988447889 hasRelatedWork W2605394509 @default.
- W2988447889 hasRelatedWork W2770614059 @default.
- W2988447889 hasRelatedWork W2945539599 @default.
- W2988447889 hasRelatedWork W2970527344 @default.
- W2988447889 hasRelatedWork W2985447045 @default.
- W2988447889 hasRelatedWork W3003884321 @default.
- W2988447889 hasRelatedWork W3014383596 @default.
- W2988447889 hasRelatedWork W3030032507 @default.
- W2988447889 hasRelatedWork W3045161410 @default.
- W2988447889 hasRelatedWork W4231443010 @default.
- W2988447889 hasVolume "1" @default.
- W2988447889 isParatext "false" @default.
- W2988447889 isRetracted "false" @default.
- W2988447889 magId "2988447889" @default.
- W2988447889 workType "article" @default.