Matches in SemOpenAlex for { <https://semopenalex.org/work/W2988503910> ?p ?o ?g. }
- W2988503910 abstract "Abstract Genome-wide association studies (GWAS) in samples of European ancestry have identified thousands of genetic variants associated with complex traits in humans. However, it remains largely unclear whether these associations can be used in non-European populations. Here, we seek to quantify the proportion of genetic variation for a complex trait shared between continental populations. We estimated the between-population correlation of genetic effects at all SNPs ( r g ) or genome-wide significant SNPs ( r g(GWS) ) for height and body mass index (BMI) in samples of European (EUR; n = 49,839) and African (AFR; n = 17,426) ancestry. The between EUR and AFR was 0.75 (s. e. = 0.035) for height and 0.68 (s. e. = 0.062) for BMI, and the corresponding was 0.82 (s. e. = 0.030) for height and 0.87 (s. e. = 0.064) for BMI, suggesting that a large proportion of GWAS findings discovered in Europeans are likely applicable to non-Europeans for height and BMI. There was no evidence that differs in SNP groups with different levels of between-population difference in allele frequency or linkage disequilibrium, which, however, can be due to the lack of power." @default.
- W2988503910 created "2019-11-22" @default.
- W2988503910 creator A5002628620 @default.
- W2988503910 creator A5006713189 @default.
- W2988503910 creator A5018863416 @default.
- W2988503910 creator A5022989604 @default.
- W2988503910 creator A5025712490 @default.
- W2988503910 creator A5065532777 @default.
- W2988503910 creator A5087258668 @default.
- W2988503910 creator A5089956650 @default.
- W2988503910 date "2019-11-14" @default.
- W2988503910 modified "2023-10-16" @default.
- W2988503910 title "Quantifying genetic heterogeneity between continental populations for human height and body mass index" @default.
- W2988503910 cites W1014257459 @default.
- W2988503910 cites W1514567872 @default.
- W2988503910 cites W1966803214 @default.
- W2988503910 cites W1972045576 @default.
- W2988503910 cites W1978145421 @default.
- W2988503910 cites W1992436001 @default.
- W2988503910 cites W2033151532 @default.
- W2988503910 cites W2039153962 @default.
- W2988503910 cites W2043913929 @default.
- W2988503910 cites W2087546077 @default.
- W2988503910 cites W2095829498 @default.
- W2988503910 cites W2098143048 @default.
- W2988503910 cites W2102270144 @default.
- W2988503910 cites W2105855535 @default.
- W2988503910 cites W2114263882 @default.
- W2988503910 cites W2117904018 @default.
- W2988503910 cites W2139852278 @default.
- W2988503910 cites W2145604455 @default.
- W2988503910 cites W2152120766 @default.
- W2988503910 cites W2155496693 @default.
- W2988503910 cites W2161633633 @default.
- W2988503910 cites W2162301803 @default.
- W2988503910 cites W2167758329 @default.
- W2988503910 cites W2174238475 @default.
- W2988503910 cites W2188707104 @default.
- W2988503910 cites W2229599978 @default.
- W2988503910 cites W2438256301 @default.
- W2988503910 cites W2580618078 @default.
- W2988503910 cites W2598022332 @default.
- W2988503910 cites W2603227143 @default.
- W2988503910 cites W2725988230 @default.
- W2988503910 cites W2733451889 @default.
- W2988503910 cites W2737435306 @default.
- W2988503910 cites W2755116403 @default.
- W2988503910 cites W2764167548 @default.
- W2988503910 cites W2769205163 @default.
- W2988503910 cites W2774504697 @default.
- W2988503910 cites W2789305195 @default.
- W2988503910 cites W2789833091 @default.
- W2988503910 cites W2799314239 @default.
- W2988503910 cites W2802784998 @default.
- W2988503910 cites W2898134536 @default.
- W2988503910 cites W2901303766 @default.
- W2988503910 cites W2903167678 @default.
- W2988503910 cites W2903782905 @default.
- W2988503910 cites W2916332932 @default.
- W2988503910 cites W2932671560 @default.
- W2988503910 cites W2940173651 @default.
- W2988503910 cites W2952883732 @default.
- W2988503910 doi "https://doi.org/10.1101/839373" @default.
- W2988503910 hasPublicationYear "2019" @default.
- W2988503910 type Work @default.
- W2988503910 sameAs 2988503910 @default.
- W2988503910 citedByCount "4" @default.
- W2988503910 countsByYear W29885039102019 @default.
- W2988503910 countsByYear W29885039102020 @default.
- W2988503910 countsByYear W29885039102021 @default.
- W2988503910 crossrefType "posted-content" @default.
- W2988503910 hasAuthorship W2988503910A5002628620 @default.
- W2988503910 hasAuthorship W2988503910A5006713189 @default.
- W2988503910 hasAuthorship W2988503910A5018863416 @default.
- W2988503910 hasAuthorship W2988503910A5022989604 @default.
- W2988503910 hasAuthorship W2988503910A5025712490 @default.
- W2988503910 hasAuthorship W2988503910A5065532777 @default.
- W2988503910 hasAuthorship W2988503910A5087258668 @default.
- W2988503910 hasAuthorship W2988503910A5089956650 @default.
- W2988503910 hasBestOaLocation W29885039101 @default.
- W2988503910 hasConcept C104317684 @default.
- W2988503910 hasConcept C106208931 @default.
- W2988503910 hasConcept C134018914 @default.
- W2988503910 hasConcept C135763542 @default.
- W2988503910 hasConcept C139275648 @default.
- W2988503910 hasConcept C144024400 @default.
- W2988503910 hasConcept C149923435 @default.
- W2988503910 hasConcept C153209595 @default.
- W2988503910 hasConcept C180754005 @default.
- W2988503910 hasConcept C186413461 @default.
- W2988503910 hasConcept C2780221984 @default.
- W2988503910 hasConcept C2908647359 @default.
- W2988503910 hasConcept C35605836 @default.
- W2988503910 hasConcept C37463918 @default.
- W2988503910 hasConcept C54355233 @default.
- W2988503910 hasConcept C78458016 @default.
- W2988503910 hasConcept C81941488 @default.
- W2988503910 hasConcept C86803240 @default.
- W2988503910 hasConcept C9287583 @default.
- W2988503910 hasConceptScore W2988503910C104317684 @default.