FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2988581737> ?p ?o ?g. }

• W2988581737 endingPage "954" @default.
• W2988581737 startingPage "943" @default.
• W2988581737 abstract "Left ventricular pressure overload is associated with activation of the cardiac renin-angiotensin system, which may contribute to myocardial fibrosis and worse clinical outcomes. We sought to assess the association between treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) at baseline and clinical outcomes in patients with symptomatic, severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) in the PARTNER 2 trial and registries.A total of 3979 intermediate, high, or prohibitive risk patients who underwent TAVR in the PARTNER 2 trial and registries (excluding the valve in valve registry) were included in the study. Clinical outcomes at 2 years were compared according to baseline ACEI/ARB treatment status using Kaplan-Meier event rates and study-stratified multivariable Cox proportional hazards regression models. Sensitivity analysis was conducted using propensity score matching. Of 3979 patients who were included in the current analysis, 1736 (43.6%) were treated and 2243 (56.4%) were not treated with ACEI/ARB at baseline. Treatment with ACEI/ARB was associated with lower 2-year all-cause mortality (18.6% vs. 27.5%, P < 0.0001), cardiovascular mortality (12.3% vs. 17.9%, P < 0.0001), and non-cardiovascular mortality (7.2% vs. 11.7%, P < 0.0001). Angiotensin-converting enzyme inhibitor/ARB treatment at baseline remained independently associated with a lower hazard of 2-year all-cause and cardiovascular mortality after multivariable adjustment, and propensity score matching.In a large cohort of patients with severe symptomatic AS from the PARTNER 2 trial and registries, ACEI/ARB treatment at baseline was independently associated with a lower risk of 2-year all-cause and cardiovascular mortality." @default.
• W2988581737 created "2019-11-22" @default.
• W2988581737 creator A5007473059 @default.
• W2988581737 creator A5010190927 @default.
• W2988581737 creator A5019475815 @default.
• W2988581737 creator A5026877561 @default.
• W2988581737 creator A5031813912 @default.
• W2988581737 creator A5041084808 @default.
• W2988581737 creator A5045000426 @default.
• W2988581737 creator A5046037086 @default.
• W2988581737 creator A5056944701 @default.
• W2988581737 creator A5057932551 @default.
• W2988581737 creator A5058875978 @default.
• W2988581737 creator A5060412536 @default.
• W2988581737 creator A5063272468 @default.
• W2988581737 creator A5065510659 @default.
• W2988581737 creator A5077395825 @default.
• W2988581737 creator A5085853649 @default.
• W2988581737 creator A5086890034 @default.
• W2988581737 date "2019-11-11" @default.
• W2988581737 modified "2023-09-27" @default.
• W2988581737 title "Impact of renin–angiotensin system inhibitors on clinical outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement: an analysis of from the PARTNER 2 trial and registries" @default.
• W2988581737 cites W1977068851 @default.
• W2988581737 cites W1984323565 @default.
• W2988581737 cites W1989846600 @default.
• W2988581737 cites W1993630998 @default.
• W2988581737 cites W2004058836 @default.
• W2988581737 cites W2010890329 @default.
• W2988581737 cites W2018353023 @default.
• W2988581737 cites W2020456856 @default.
• W2988581737 cites W2025543748 @default.
• W2988581737 cites W2066778848 @default.
• W2988581737 cites W2079157229 @default.
• W2988581737 cites W2093344684 @default.
• W2988581737 cites W2095923547 @default.
• W2988581737 cites W2106855216 @default.
• W2988581737 cites W2118289643 @default.
• W2988581737 cites W2126444361 @default.
• W2988581737 cites W2126475326 @default.
• W2988581737 cites W2138054764 @default.
• W2988581737 cites W2169293389 @default.
• W2988581737 cites W2186188224 @default.
• W2988581737 cites W2324073140 @default.
• W2988581737 cites W2326187533 @default.
• W2988581737 cites W2329458628 @default.
• W2988581737 cites W2333519782 @default.
• W2988581737 cites W2510823453 @default.
• W2988581737 cites W2570810965 @default.
• W2988581737 cites W2751630023 @default.
• W2988581737 cites W2760172151 @default.
• W2988581737 cites W2761865976 @default.
• W2988581737 cites W2792283746 @default.
• W2988581737 cites W2902901219 @default.
• W2988581737 cites W4239973835 @default.
• W2988581737 doi "https://doi.org/10.1093/eurheartj/ehz769" @default.
• W2988581737 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8204653" @default.
• W2988581737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31711153" @default.
• W2988581737 hasPublicationYear "2019" @default.
• W2988581737 type Work @default.
• W2988581737 sameAs 2988581737 @default.
• W2988581737 citedByCount "31" @default.
• W2988581737 countsByYear W29885817372019 @default.
• W2988581737 countsByYear W29885817372020 @default.
• W2988581737 countsByYear W29885817372021 @default.
• W2988581737 countsByYear W29885817372022 @default.
• W2988581737 countsByYear W29885817372023 @default.
• W2988581737 crossrefType "journal-article" @default.
• W2988581737 hasAuthorship W2988581737A5007473059 @default.
• W2988581737 hasAuthorship W2988581737A5010190927 @default.
• W2988581737 hasAuthorship W2988581737A5019475815 @default.
• W2988581737 hasAuthorship W2988581737A5026877561 @default.
• W2988581737 hasAuthorship W2988581737A5031813912 @default.
• W2988581737 hasAuthorship W2988581737A5041084808 @default.
• W2988581737 hasAuthorship W2988581737A5045000426 @default.
• W2988581737 hasAuthorship W2988581737A5046037086 @default.
• W2988581737 hasAuthorship W2988581737A5056944701 @default.
• W2988581737 hasAuthorship W2988581737A5057932551 @default.
• W2988581737 hasAuthorship W2988581737A5058875978 @default.
• W2988581737 hasAuthorship W2988581737A5060412536 @default.
• W2988581737 hasAuthorship W2988581737A5063272468 @default.
• W2988581737 hasAuthorship W2988581737A5065510659 @default.
• W2988581737 hasAuthorship W2988581737A5077395825 @default.
• W2988581737 hasAuthorship W2988581737A5085853649 @default.
• W2988581737 hasAuthorship W2988581737A5086890034 @default.
• W2988581737 hasBestOaLocation W29885817372 @default.
• W2988581737 hasConcept C126322002 @default.
• W2988581737 hasConcept C164705383 @default.
• W2988581737 hasConcept C17923572 @default.
• W2988581737 hasConcept C207103383 @default.
• W2988581737 hasConcept C2776570981 @default.
• W2988581737 hasConcept C2780007028 @default.
• W2988581737 hasConcept C2780026749 @default.
• W2988581737 hasConcept C2781414266 @default.
• W2988581737 hasConcept C44249647 @default.
• W2988581737 hasConcept C50382708 @default.
• W2988581737 hasConcept C71924100 @default.
• W2988581737 hasConceptScore W2988581737C126322002 @default.
• W2988581737 hasConceptScore W2988581737C164705383 @default.

• next