FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2988803054> ?p ?o ?g. }

• W2988803054 endingPage "112355" @default.
• W2988803054 startingPage "112355" @default.
• W2988803054 abstract "Ovarian steroids modulate the neuronal structure and function during the estrous cycle, contrasting peak effects during the proestrus cycle and low effects during the metestrus cycle. An ovariectomy (OVX) decreases gonadal hormones and tests the effects of substitutive therapies. We studied female rats with a normal estrous cycle and we also studied the effects of systemic progesterone (P4, 4.0 mg/kg) or its reduced metabolite allopregnanolone (ALLO, 4.0 mg/kg, both for 10 days) in females who had had an OVX 16.5 weeks prior to the study (long-term OVX) with the novel object recognition test (NORT) for associative memory. The dendritic shape and spine density in Golgi-impregnated basal dendrites (stratum oriens) of hippocampal pyramidal neurons was also studied. Proestrus females had a better performance than metestrus or OVX females in short-term memory (tested 1 h after the acquisition phase). Proestrus and metestrus females showed better results than OVX females for long-term memory (24 h after the initial phase). Both P4 and ALLO recovered the cognitive impairment induced by long-term OVX. Also, proestrus females had a higher density of dendritic spines than metestrus females, OVX reduced the density of spines when compared to intact females, whereas both P4 and ALLO treatments increased the dendritic spine density, number of dendritic branches along the dendritic length, and branching order compared to vehicle. These data add the dendrites of the stratum oriens as an additional site for naturally occurring changes in spine density during the estrous cycle and evidence the actions of progestins in both behavioral recovery and the structural dendritic rearrangement of hippocampal pyramidal neurons in long-term OVX female rats." @default.
• W2988803054 created "2019-11-22" @default.
• W2988803054 creator A5008988085 @default.
• W2988803054 creator A5012752153 @default.
• W2988803054 creator A5029229294 @default.
• W2988803054 creator A5044170249 @default.
• W2988803054 creator A5066947833 @default.
• W2988803054 creator A5068427240 @default.
• W2988803054 creator A5070572888 @default.
• W2988803054 creator A5079231073 @default.
• W2988803054 date "2020-02-01" @default.
• W2988803054 modified "2023-09-29" @default.
• W2988803054 title "Cyclic changes and actions of progesterone and allopregnanolone on cognition and hippocampal basal (stratum oriens) dendritic spines of female rats" @default.
• W2988803054 cites W1440335865 @default.
• W2988803054 cites W1484602144 @default.
• W2988803054 cites W1526463794 @default.
• W2988803054 cites W1848156198 @default.
• W2988803054 cites W1944155217 @default.
• W2988803054 cites W1965340851 @default.
• W2988803054 cites W1985450720 @default.
• W2988803054 cites W1985891090 @default.
• W2988803054 cites W1985940694 @default.
• W2988803054 cites W1989799361 @default.
• W2988803054 cites W1989982790 @default.
• W2988803054 cites W1990382521 @default.
• W2988803054 cites W1990833831 @default.
• W2988803054 cites W1994645839 @default.
• W2988803054 cites W1995042090 @default.
• W2988803054 cites W2006162269 @default.
• W2988803054 cites W2009410204 @default.
• W2988803054 cites W2020040226 @default.
• W2988803054 cites W2022691706 @default.
• W2988803054 cites W2028496416 @default.
• W2988803054 cites W2044150847 @default.
• W2988803054 cites W2049939318 @default.
• W2988803054 cites W2053686316 @default.
• W2988803054 cites W2056224205 @default.
• W2988803054 cites W2075133445 @default.
• W2988803054 cites W2076800034 @default.
• W2988803054 cites W2078529082 @default.
• W2988803054 cites W2079286004 @default.
• W2988803054 cites W2081698851 @default.
• W2988803054 cites W2084425006 @default.
• W2988803054 cites W2087680546 @default.
• W2988803054 cites W2087816267 @default.
• W2988803054 cites W2093154531 @default.
• W2988803054 cites W2097243895 @default.
• W2988803054 cites W2111155182 @default.
• W2988803054 cites W2122253235 @default.
• W2988803054 cites W2130186201 @default.
• W2988803054 cites W2136249808 @default.
• W2988803054 cites W2146599264 @default.
• W2988803054 cites W2149246533 @default.
• W2988803054 cites W2157450506 @default.
• W2988803054 cites W2171196764 @default.
• W2988803054 cites W2288882244 @default.
• W2988803054 cites W2333763415 @default.
• W2988803054 cites W2417763540 @default.
• W2988803054 cites W2467383487 @default.
• W2988803054 cites W2587057685 @default.
• W2988803054 cites W2767588029 @default.
• W2988803054 cites W2773657956 @default.
• W2988803054 cites W2779887811 @default.
• W2988803054 cites W2784207714 @default.
• W2988803054 cites W2889177916 @default.
• W2988803054 cites W2935973331 @default.
• W2988803054 cites W2986082729 @default.
• W2988803054 cites W99928629 @default.
• W2988803054 doi "https://doi.org/10.1016/j.bbr.2019.112355" @default.
• W2988803054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31730784" @default.
• W2988803054 hasPublicationYear "2020" @default.
• W2988803054 type Work @default.
• W2988803054 sameAs 2988803054 @default.
• W2988803054 citedByCount "9" @default.
• W2988803054 countsByYear W29888030542020 @default.
• W2988803054 countsByYear W29888030542021 @default.
• W2988803054 countsByYear W29888030542022 @default.
• W2988803054 countsByYear W29888030542023 @default.
• W2988803054 crossrefType "journal-article" @default.
• W2988803054 hasAuthorship W2988803054A5008988085 @default.
• W2988803054 hasAuthorship W2988803054A5012752153 @default.
• W2988803054 hasAuthorship W2988803054A5029229294 @default.
• W2988803054 hasAuthorship W2988803054A5044170249 @default.
• W2988803054 hasAuthorship W2988803054A5066947833 @default.
• W2988803054 hasAuthorship W2988803054A5068427240 @default.
• W2988803054 hasAuthorship W2988803054A5070572888 @default.
• W2988803054 hasAuthorship W2988803054A5079231073 @default.
• W2988803054 hasConcept C126322002 @default.
• W2988803054 hasConcept C134018914 @default.
• W2988803054 hasConcept C148762608 @default.
• W2988803054 hasConcept C15744967 @default.
• W2988803054 hasConcept C168258287 @default.
• W2988803054 hasConcept C169760540 @default.
• W2988803054 hasConcept C170493617 @default.
• W2988803054 hasConcept C174884520 @default.
• W2988803054 hasConcept C185592680 @default.
• W2988803054 hasConcept C1998276 @default.
• W2988803054 hasConcept C2778024521 @default.

• next