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- W2988896135 abstract "Summary Accurate reference genomes have become indispensable tools for characterization of genetic and functional variations. Here we generated a high-quality assembly of the melon Payzawat using a combination of short-read sequencing, single-molecule real-time sequencing, Hi-C, and a high-density genetic map. The final 12 chromosome-level scaffolds cover ∼94.13% of the estimated genome (398.57 Mb). Compared with the published DHL92 genome, our assembly exhibits a 157-fold increase in contig length and remarkable improvements in the assembly of centromeres and telomeres. Six genes within STHQF12.4 on pseudochromosome 12, identified from whole-genome comparison between Payzawat and DHL92, may explain a considerable proportion of the skin thickness. In addition, our population study showed that melon domesticated at multiple times from whole-genome perspective and melons in China are introduced from different routes. Selective sweeps underlying the genes related to desirable traits, haplotypes of alleles associated with agronomic traits, and the variants from resequencing data enable efficient breeding." @default.
- W2988896135 created "2019-11-22" @default.
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- W2988896135 date "2019-12-01" @default.
- W2988896135 modified "2023-10-14" @default.
- W2988896135 title "A High-Quality Melon Genome Assembly Provides Insights into Genetic Basis of Fruit Trait Improvement" @default.
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- W2988896135 doi "https://doi.org/10.1016/j.isci.2019.10.049" @default.
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