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- W2989035462 abstract "Ischemia-reperfusion (I/R) injury is a common pathological process, which may lead to dysfunctions and failures of multiple organs. A flawless medical way of endogenous therapeutic target can illuminate accurate clinical applications. γ -Aminobutyric acid (GABA) has been known as a marker in I/R injury of the central nervous system (mainly in the brain) for a long time, and it may play a vital role in the occurrence of I/R injury. It has been observed that throughout cerebral I/R, levels, syntheses, releases, metabolisms, receptors, and transmissions of GABA undergo complex pathological variations. Scientists have investigated the GABAergic enhancers for attenuating cerebral I/R injury; however, discussions on existing problems and mechanisms of available drugs were seldom carried out so far. Therefore, this review would summarize the process of pathological variations in the GABA system under cerebral I/R injury and will cover corresponding probable issues and mechanisms in using GABA-related drugs to illuminate the concern about clinical illness for accurately preventing cerebral I/R injury. In addition, the study will summarize the increasing GABA signals that can prevent I/R injuries occurring in peripheral organs, and the roles of GABA were also discussed correspondingly." @default.
- W2989035462 created "2019-11-22" @default.
- W2989035462 creator A5007082560 @default.
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- W2989035462 creator A5029495726 @default.
- W2989035462 creator A5075136340 @default.
- W2989035462 creator A5081180912 @default.
- W2989035462 date "2019-11-11" @default.
- W2989035462 modified "2023-10-18" @default.
- W2989035462 title "The Roles of GABA in Ischemia-Reperfusion Injury in the Central Nervous System and Peripheral Organs" @default.
- W2989035462 cites W1035422823 @default.
- W2989035462 cites W1127532827 @default.
- W2989035462 cites W1559241997 @default.
- W2989035462 cites W1605590279 @default.
- W2989035462 cites W1608349461 @default.
- W2989035462 cites W1722077336 @default.
- W2989035462 cites W1892125219 @default.
- W2989035462 cites W1914573874 @default.
- W2989035462 cites W1915010695 @default.
- W2989035462 cites W1948902480 @default.
- W2989035462 cites W1964496693 @default.
- W2989035462 cites W1964723546 @default.
- W2989035462 cites W1966089287 @default.
- W2989035462 cites W1967113029 @default.
- W2989035462 cites W1970188265 @default.
- W2989035462 cites W1971126847 @default.
- W2989035462 cites W1971140349 @default.
- W2989035462 cites W1974582869 @default.
- W2989035462 cites W1977734010 @default.
- W2989035462 cites W1978018687 @default.
- W2989035462 cites W1978885851 @default.
- W2989035462 cites W1979896640 @default.
- W2989035462 cites W1981917443 @default.
- W2989035462 cites W1982681156 @default.
- W2989035462 cites W1985451434 @default.
- W2989035462 cites W1991485851 @default.
- W2989035462 cites W1992571619 @default.
- W2989035462 cites W1992732988 @default.
- W2989035462 cites W1992891849 @default.
- W2989035462 cites W1993698747 @default.
- W2989035462 cites W1995684224 @default.
- W2989035462 cites W1995733166 @default.
- W2989035462 cites W1999106379 @default.
- W2989035462 cites W1999957169 @default.
- W2989035462 cites W2000609422 @default.
- W2989035462 cites W2000614198 @default.
- W2989035462 cites W2006771521 @default.
- W2989035462 cites W2006972100 @default.
- W2989035462 cites W2007327549 @default.
- W2989035462 cites W2007576383 @default.
- W2989035462 cites W2010505933 @default.
- W2989035462 cites W2011048722 @default.
- W2989035462 cites W2013247246 @default.
- W2989035462 cites W2016105788 @default.
- W2989035462 cites W2017074988 @default.
- W2989035462 cites W2017988998 @default.
- W2989035462 cites W2020716000 @default.
- W2989035462 cites W2021782449 @default.
- W2989035462 cites W2022443796 @default.
- W2989035462 cites W2023797935 @default.
- W2989035462 cites W2025368995 @default.
- W2989035462 cites W2027671995 @default.
- W2989035462 cites W2028644532 @default.
- W2989035462 cites W2030857678 @default.
- W2989035462 cites W2031287609 @default.
- W2989035462 cites W2034147495 @default.
- W2989035462 cites W2036342829 @default.
- W2989035462 cites W2037688699 @default.
- W2989035462 cites W2038254164 @default.
- W2989035462 cites W2038477005 @default.
- W2989035462 cites W2041293915 @default.
- W2989035462 cites W2042131974 @default.
- W2989035462 cites W2043321957 @default.
- W2989035462 cites W2043544598 @default.
- W2989035462 cites W2044574613 @default.
- W2989035462 cites W2048449841 @default.
- W2989035462 cites W2049380458 @default.
- W2989035462 cites W2049501171 @default.
- W2989035462 cites W2050634275 @default.
- W2989035462 cites W2050901041 @default.
- W2989035462 cites W2053204649 @default.
- W2989035462 cites W2053210741 @default.
- W2989035462 cites W2053581898 @default.
- W2989035462 cites W2054273882 @default.
- W2989035462 cites W2054945824 @default.
- W2989035462 cites W2055007110 @default.
- W2989035462 cites W2056417039 @default.
- W2989035462 cites W2056598331 @default.
- W2989035462 cites W2058722821 @default.
- W2989035462 cites W2062232335 @default.
- W2989035462 cites W2064447601 @default.
- W2989035462 cites W2065944026 @default.
- W2989035462 cites W2066208396 @default.
- W2989035462 cites W2071756845 @default.
- W2989035462 cites W2075046188 @default.
- W2989035462 cites W2076936310 @default.
- W2989035462 cites W2080403961 @default.