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- W2989374258 abstract "Abstract: Objective, Materials and Methods: To examine the effect of immunotherapy (IT) on the level of serum interferon-gamma (IFN-g) and T-lymphocyte subgroups in allergic individuals, five study groups including 40 patients with allergic rhinitis and 10 healthy individuals were formed. Group I: 10 participants whose IFN-g levels were measured before the IT administration Group II: 10 participants whose IFN-g levels were measured after the IT administration Group III: 10 participants whose IFN-g levels were measured in the 3 rd control year after the IT administration Group IV: 10 participants whose T4 and T8 lymphocyte levels were measured before and after the IT administration Group V-Control group: 10 participants whose IFN-g levels were measured Results : In Group I, serum IFN-g levels before the IT administration were examined and compared with that of the control group and no significant difference was found. In Group II, IFN-g levels after IT administration were investigated. IFN-g levels after IT administration were compared with those of Group I and the control group and a significant increase was observed in IFN-g level. Similarly, serum IFN-g levels in the 3 rd control year after IT administration in Group III were compared with those of the control group and Group I, and they were found significantly higher. T4, T8 levels and the rate of T4/ T8 in the peripheral blood before and after the IT administration in Group IV were examined. Conclusion: There was a decrease in T4 level, an increase in T8 and decrease in the rate of T4/T8 after the IT administration. Oz: Amac, materiyal ve metod: Allerjik bireylerde immunoterapinin (IT) serum interferon-gama (IFN-g) duzeyinde ve T-lenfosit subgruplarina olan etkisini arastirmak amaciyla 40 allerjik rinitli hasta ile 10 saglikli bireylerden bes calisma grubu olusturuldu. I. Grup: IT oncesi IFN-g olculen 10 kisi II. Grup: IT bitiminde IFN-g duzeyleri olculen 10 kisi III. Grup: IT bitiminden 3. kontrol yilinda IFN-g duzeyleri olculen 10 kisi IV. Grup: IT oncesi ve sonrasi T4,T8 lenfosit duzeyleri olculen 10 kisi V. Grup: kontrol grubu IFN-g duzeyleri olculen 10 kisi Sonuc: I.grupta, IT oncesi serum IFN-g duzeyi bakilarak kontrol grubu ile karsilastirildi. Ikisi arasinda anlamli bir fark bulunmadi. II.grupta ise IT sonrasi IFN-g duzeyine bakildi. IT sonrasi IFN-g duzeyi, I. grup ve kontrol grubu duzeyleri ile karsilastirilarak IFN-g seviyesinde belirgin yukselme goruldu. Ayni sekilde III. grupta IT sonrasi 3. kontrol yilinda bakilan serum IFN-g duzeyi, I. grup ve kontrol grubu duzeyleri ile karsilastirilarak anlamli miktarda yuksek bulundu. IV. grupta ise IT oncesi ve sonrasi periferik kandaki T4, T8 ve T4/T8miktarlarina bakildi. Tartisma: IT sonrasinda T4 duzeyinde azalma, T8 duzeyinde artma ve T4/T8 oraninda dusme goruldu." @default.
- W2989374258 created "2019-11-22" @default.
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- W2989374258 date "2019-10-15" @default.
- W2989374258 modified "2023-10-04" @default.
- W2989374258 title "Effects of Immunotherapy on T-lymphocyte and Cytokine Composition" @default.
- W2989374258 hasPublicationYear "2019" @default.
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