Matches in SemOpenAlex for { <https://semopenalex.org/work/W2989403735> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2989403735 endingPage "25" @default.
- W2989403735 startingPage "21" @default.
- W2989403735 abstract "Abstract Hangovers are associated with negative economic consequences due to decreased job performance or frequent visits to physicians. Thus, a new strategy for the alleviation of hangover-related symptoms is needed to avoid this detriment to society. The purpose of this nationwide randomized, double-blind, placebo-controlled physicians’ trial was to evaluate the efficacy of loxoprofen sodium for the alleviation of fatigue, headache, and nausea after hangover. A total of 229 participants were randomized to receive loxoprofen sodium (60 mg once orally) or placebo. The study was closed when the first 150 participants (n = 74 in the loxoprofen vs. n = 76 in the placebo groups) experienced hangovers. The primary endpoint was set as the difference in severity of general fatigue before and 3 h after taking the test drugs and was evaluated using a visual analogue scale. Secondary endpoints included difference in severity of headache, nausea, and incidence of adverse events. The study participants were 34 (interquartile range; 30–39) years old, 92.0% were men, and both groups were comparable for baseline characteristics. The alleviation of general fatigue did not differ statistically between the loxoprofen and placebo groups (24 [14–49] vs. 19 [9–35], p = 0.07). However, the alleviation of headache was statistically greater in the loxoprofen group (25 [10–50] vs. 10 [2–30], adjusted difference 14, 95% confidence interval 8–21, p" @default.
- W2989403735 created "2019-11-22" @default.
- W2989403735 creator A5020836274 @default.
- W2989403735 creator A5037187093 @default.
- W2989403735 creator A5049914126 @default.
- W2989403735 creator A5056034440 @default.
- W2989403735 creator A5067046455 @default.
- W2989403735 date "2020-05-01" @default.
- W2989403735 modified "2023-10-16" @default.
- W2989403735 title "A nationwide randomized, double-blind, placebo-controlled physicians’ trial of loxoprofen for the treatment of fatigue, headache, and nausea after hangovers" @default.
- W2989403735 cites W1987324044 @default.
- W2989403735 cites W2000416147 @default.
- W2989403735 cites W2120857280 @default.
- W2989403735 cites W2128680329 @default.
- W2989403735 cites W2138694780 @default.
- W2989403735 cites W2158037384 @default.
- W2989403735 cites W2162413910 @default.
- W2989403735 cites W2167234907 @default.
- W2989403735 cites W2317888114 @default.
- W2989403735 cites W2327254702 @default.
- W2989403735 cites W2617572893 @default.
- W2989403735 cites W36354637 @default.
- W2989403735 doi "https://doi.org/10.1016/j.alcohol.2019.10.006" @default.
- W2989403735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31689482" @default.
- W2989403735 hasPublicationYear "2020" @default.
- W2989403735 type Work @default.
- W2989403735 sameAs 2989403735 @default.
- W2989403735 citedByCount "4" @default.
- W2989403735 countsByYear W29894037352020 @default.
- W2989403735 countsByYear W29894037352021 @default.
- W2989403735 countsByYear W29894037352022 @default.
- W2989403735 crossrefType "journal-article" @default.
- W2989403735 hasAuthorship W2989403735A5020836274 @default.
- W2989403735 hasAuthorship W2989403735A5037187093 @default.
- W2989403735 hasAuthorship W2989403735A5049914126 @default.
- W2989403735 hasAuthorship W2989403735A5056034440 @default.
- W2989403735 hasAuthorship W2989403735A5067046455 @default.
- W2989403735 hasBestOaLocation W29894037351 @default.
- W2989403735 hasConcept C142724271 @default.
- W2989403735 hasConcept C1862650 @default.
- W2989403735 hasConcept C204787440 @default.
- W2989403735 hasConcept C27081682 @default.
- W2989403735 hasConcept C2780580376 @default.
- W2989403735 hasConcept C2991744798 @default.
- W2989403735 hasConcept C42219234 @default.
- W2989403735 hasConcept C71924100 @default.
- W2989403735 hasConceptScore W2989403735C142724271 @default.
- W2989403735 hasConceptScore W2989403735C1862650 @default.
- W2989403735 hasConceptScore W2989403735C204787440 @default.
- W2989403735 hasConceptScore W2989403735C27081682 @default.
- W2989403735 hasConceptScore W2989403735C2780580376 @default.
- W2989403735 hasConceptScore W2989403735C2991744798 @default.
- W2989403735 hasConceptScore W2989403735C42219234 @default.
- W2989403735 hasConceptScore W2989403735C71924100 @default.
- W2989403735 hasLocation W29894037351 @default.
- W2989403735 hasLocation W29894037352 @default.
- W2989403735 hasOpenAccess W2989403735 @default.
- W2989403735 hasPrimaryLocation W29894037351 @default.
- W2989403735 hasRelatedWork W1589162572 @default.
- W2989403735 hasRelatedWork W1992517622 @default.
- W2989403735 hasRelatedWork W2029338556 @default.
- W2989403735 hasRelatedWork W2033995784 @default.
- W2989403735 hasRelatedWork W2070087168 @default.
- W2989403735 hasRelatedWork W2071509931 @default.
- W2989403735 hasRelatedWork W2162983960 @default.
- W2989403735 hasRelatedWork W2402198224 @default.
- W2989403735 hasRelatedWork W2524826251 @default.
- W2989403735 hasRelatedWork W1491509015 @default.
- W2989403735 hasVolume "84" @default.
- W2989403735 isParatext "false" @default.
- W2989403735 isRetracted "false" @default.
- W2989403735 magId "2989403735" @default.
- W2989403735 workType "article" @default.