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- W2989591778 abstract "Introduction: In line with the “one airway, one disease” concept allergic rhinitis (AR) and asthma often coexist and the disease mechanism occurring in the upper airway may mirror lower airway events. Eosinophils play an essential role in inflammation of the united airway. The association between blood eosinophil count and asthma control has already been demonstrated but data on such relation with AR control is lacking. The Objective: of our study was to determine whether blood eosinophil count is associated with control of allergic rhinitis. Methods: In this cross-sectional study 124 patients [77 (60.63%) men; mean age 27.92 (SD11.62)] having treatment for AR with/without asthma were evaluated. Rhinitis Control Assessment Test (RCAT) was used for the assessment of rhinitis control. Blood eosinophil count was measured in cells/ml. Results: When assessed by RCAT 49 (39.52%) patients were not well controlled (score ≤ 21). Mean eosinophil count in not-well controlled patients was 316.07 cells/mL (sem 15.17 cells/mL) and 291.06 cells/mL (sem 14.85 cells/mL) in well controlled with no significant difference between controlled and not-well controlled AR (p > 0 05). There was no relation between control of AR and blood eosinophil count (R-0.026; p >0.05). A significantly higher blood eosinophil count was established in patients with asthma comorbidity (p Conclusion: Although essential for inflammation of the united airway, analysis of these findings indicate that unlike asthma blood eosinophil count is not associated with control of AR but with asthma comorbidity." @default.
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- W2989591778 date "2019-09-28" @default.
- W2989591778 modified "2023-09-27" @default.
- W2989591778 title "Association between blood eosinophil count and control of allergic rhinitis: does it exist?" @default.
- W2989591778 doi "https://doi.org/10.1183/13993003.congress-2019.pa4400" @default.
- W2989591778 hasPublicationYear "2019" @default.
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