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- W2989597002 abstract "Particulate matter (PM) air pollution is known to exacerbate asthma symptoms in children; however, it is still unclear which metric (particle size, morphology or chemical composition) of PM is most relevant to respiratory health. Most studies have focused on the health impacts of fine PM (PM2.5, particles with diameter less than 2.5 μm), yet recent evidence suggests that health effects may be more strongly related to the ultrafine particulate (UFP) portion of PM exposure. Due to complexities of exposure assessment and the lack of a regulatory monitoring network for UFP, few epidemiologic studies have evaluated the relationship between UFP and respiratory health. The aim of this work is to determine which factors of PM exposure, including UFP, microenvironment, and peak exposure, are associated with respiratory effects. We conducted personal exposure assessment in a panel of 15 children with asthma, each of whom were followed for 7 days with 4 days of continuous monitoring of PM (10-s resolution), geographic location via GPS, biomarkers (urinary LTE4), and 7 days of asthma symptoms reported via text message. Ultrafine PM was measured using a Partector (expressed as lung deposited surface area; CH Technologies) and fine PM mass was measured with a MicroPEM (RTI International). Inner-city children were exposed to levels of PM mass often exceeding WHO recommendations for PM2.5 in indoor air (24-hr mean (N=58): 23.6 μg/m3; range: 1.4-132.2 μg/m3). Ultrafine particle exposures (24-hr mean (N=58): 37 μm2/cm3; range: 3-185 μm2/cm3) typically varied over 2 orders of magnitude within 24-hours and showed relatively low correlation with PM2.5 (mean Pearson coefficient of 1-minute measurements across 58 sampling days was 0.29). Exposures to ultrafine particles tended to be highest at home during exposure to secondhand smoke and cooking events. Exposures while commuting were also high, especially when walking." @default.
- W2989597002 created "2019-12-05" @default.
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- W2989597002 date "2018-09-24" @default.
- W2989597002 modified "2023-09-25" @default.
- W2989597002 title "Personal Exposures to Ultrafine Particles among Asthmatic Kids: Differences between UFP and PM2.5" @default.
- W2989597002 doi "https://doi.org/10.1289/isesisee.2018.s01.04.31" @default.
- W2989597002 hasPublicationYear "2018" @default.
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