Matches in SemOpenAlex for { <https://semopenalex.org/work/W2989622942> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2989622942 endingPage "e8" @default.
- W2989622942 startingPage "e5" @default.
- W2989622942 abstract "Intrathecal baclofen (ITB) is a mainstay of treatment for patients with chronic spasticity. Up to 40% of all patients receiving ITB experience overdose or withdrawal symptoms, which in the most severe cases can lead to multisystem organ failure and death. There is currently no well-established treatment for ITB withdrawal. One previous case report details an intubated pediatric patient who underwent baclofen pump removal in which dexmedetomidine was used in combination with other medications to prevent baclofen withdrawal.We report a case of baclofen withdrawal where the decision was made to initiate a dexmedetomidine infusion, with subsequent improvement of the patient's hypertension and tachycardia. At no point during her stay did the patient require intubation for airway protection, and the patient was ultimately discharged to her previous nursing facility on hospital day 9 with no new neurologic deficits. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Emergency physicians should be aware of dexmedetomidine as a promising option for the treatment of ITB withdrawal in the acute setting. Although little evidence is currently present, dexmedetomidine was used successfully in this case, and should be considered as a temporizing treatment for ITB withdrawal. Dexmedetomidine holds promise in the management of ITB withdrawal compared to other previously described treatments, including oral baclofen, cyproheptadine, and dantrolene. In addition, dexmedetomidine has a superior safety profile compared to propofol or large doses of benzodiazepines. Further research will be useful in supporting the use of dexmedetomidine for this purpose." @default.
- W2989622942 created "2019-12-05" @default.
- W2989622942 creator A5008683871 @default.
- W2989622942 creator A5046631624 @default.
- W2989622942 creator A5046899275 @default.
- W2989622942 creator A5090279804 @default.
- W2989622942 date "2020-01-01" @default.
- W2989622942 modified "2023-10-01" @default.
- W2989622942 title "Dexmedetomidine for Acute Management of Intrathecal Baclofen Withdrawal" @default.
- W2989622942 cites W1936894805 @default.
- W2989622942 cites W1967039435 @default.
- W2989622942 cites W1994030454 @default.
- W2989622942 cites W1997759536 @default.
- W2989622942 cites W1997879300 @default.
- W2989622942 cites W2053993055 @default.
- W2989622942 cites W2093719422 @default.
- W2989622942 cites W2128561050 @default.
- W2989622942 cites W2135672238 @default.
- W2989622942 cites W2589329533 @default.
- W2989622942 cites W2781130250 @default.
- W2989622942 cites W2805387443 @default.
- W2989622942 cites W630657035 @default.
- W2989622942 doi "https://doi.org/10.1016/j.jemermed.2019.09.043" @default.
- W2989622942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31759793" @default.
- W2989622942 hasPublicationYear "2020" @default.
- W2989622942 type Work @default.
- W2989622942 sameAs 2989622942 @default.
- W2989622942 citedByCount "4" @default.
- W2989622942 countsByYear W29896229422020 @default.
- W2989622942 countsByYear W29896229422022 @default.
- W2989622942 countsByYear W29896229422023 @default.
- W2989622942 crossrefType "journal-article" @default.
- W2989622942 hasAuthorship W2989622942A5008683871 @default.
- W2989622942 hasAuthorship W2989622942A5046631624 @default.
- W2989622942 hasAuthorship W2989622942A5046899275 @default.
- W2989622942 hasAuthorship W2989622942A5090279804 @default.
- W2989622942 hasConcept C126322002 @default.
- W2989622942 hasConcept C170493617 @default.
- W2989622942 hasConcept C2776277131 @default.
- W2989622942 hasConcept C2776814716 @default.
- W2989622942 hasConcept C2778938600 @default.
- W2989622942 hasConcept C2779012798 @default.
- W2989622942 hasConcept C2781201050 @default.
- W2989622942 hasConcept C2781302539 @default.
- W2989622942 hasConcept C42219234 @default.
- W2989622942 hasConcept C71924100 @default.
- W2989622942 hasConceptScore W2989622942C126322002 @default.
- W2989622942 hasConceptScore W2989622942C170493617 @default.
- W2989622942 hasConceptScore W2989622942C2776277131 @default.
- W2989622942 hasConceptScore W2989622942C2776814716 @default.
- W2989622942 hasConceptScore W2989622942C2778938600 @default.
- W2989622942 hasConceptScore W2989622942C2779012798 @default.
- W2989622942 hasConceptScore W2989622942C2781201050 @default.
- W2989622942 hasConceptScore W2989622942C2781302539 @default.
- W2989622942 hasConceptScore W2989622942C42219234 @default.
- W2989622942 hasConceptScore W2989622942C71924100 @default.
- W2989622942 hasIssue "1" @default.
- W2989622942 hasLocation W29896229421 @default.
- W2989622942 hasLocation W29896229422 @default.
- W2989622942 hasOpenAccess W2989622942 @default.
- W2989622942 hasPrimaryLocation W29896229421 @default.
- W2989622942 hasRelatedWork W2032029194 @default.
- W2989622942 hasRelatedWork W2168070408 @default.
- W2989622942 hasRelatedWork W2387237660 @default.
- W2989622942 hasRelatedWork W2390266119 @default.
- W2989622942 hasRelatedWork W2518123441 @default.
- W2989622942 hasRelatedWork W2560786414 @default.
- W2989622942 hasRelatedWork W3029603849 @default.
- W2989622942 hasRelatedWork W3032230163 @default.
- W2989622942 hasRelatedWork W50876771 @default.
- W2989622942 hasRelatedWork W2181574986 @default.
- W2989622942 hasVolume "58" @default.
- W2989622942 isParatext "false" @default.
- W2989622942 isRetracted "false" @default.
- W2989622942 magId "2989622942" @default.
- W2989622942 workType "article" @default.