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- W2989638197 abstract "Late in-stent restenosis remains a significant problem. Bare-metal stents were implanted into peripheral arteries in miniature swine, followed by direct intra-arterial infusion of nitric oxide–loaded echogenic liposomes (ELIPs) and anti–intercellular adhesion molecule-1 conjugated ELIPs loaded with pioglitazone exposed to an endovascular catheter with an ultrasonic core. Ultrasound-facilitated delivery of ELIP formulations into stented peripheral arteries attenuated neointimal growth. Local atheroma-targeted, ultrasound-triggered delivery of nitric oxide and pioglitazone, an anti-inflammatory peroxisome proliferator–activated receptor-γ agonist, into stented arteries has the potential to stabilize stent-induced neointimal growth and obviate the need for long-term antiplatelet therapy." @default.
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- W2989638197 date "2020-01-01" @default.
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- W2989638197 title "Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier" @default.
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- W2989638197 doi "https://doi.org/10.1016/j.jacbts.2019.09.005" @default.
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