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- W2989700058 abstract "Over recent years, green chemistry procedures have been developed to synthesize nanoparticles in eco-friendlier and less expensive ways. These procedures use natural sources such as bacteria, fungi, yeast, plants, actinomycetes, algae, or cyanobacteria, or use biomolecules such as proteins, vitamins, or pigments instead of chemical materials to fabricate salt precursors into nanoparticles.In the current investigation, we developed an effective, inexpensive, nontoxic method to synthesize silver nanoparticles (SNPs) using the cellular extract of a novel strain of cyanobacterium, Nostoc sp. Bahar M. SNPs were characterized using ultraviolet-visible spectroscopy, Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The antitumor properties of the biogenic SNPs were tested against Caco-2 cells using a cell proliferation assay and inverted light microscopy.The new strain Nostoc sp. Bahar M was able to fabricate small SNPs from silver nitrate through an eco-friendly and inexpensive biosynthesis process. SNPs synthesis was accompanied by a color transformation from pale yellow to dark brown. Ultraviolet spectroscopy showed an absorption peak at 403 nm, confirming SNPs formation. X-ray diffraction analysis indicated that the SNPs had a face-centered cubic crystalline structure. Fourier-transform infrared spectroscopy was used to identify a protein that may play an important role in SNPs biosynthesis. Scanning and transmission electron micrographs showed that the SNPs were uniformly distributed and spherical in shape, with an average diameter of 14.9 nm. Cytotoxicity assays showed that SNPs exhibited a significant dose-dependent cytotoxic activity against human colon cancer cells with an IC50 of 150 μg/mL.Nostoc sp. Bahar M provided an eco-friendly route for fabricating SNPs, which have cytotoxic activity toward Caco-2 cells." @default.
- W2989700058 created "2019-12-05" @default.
- W2989700058 creator A5086630622 @default.
- W2989700058 creator A5090543817 @default.
- W2989700058 date "2019-11-01" @default.
- W2989700058 modified "2023-10-16" @default.
- W2989700058 title "<p>Biofabrication And Antitumor Activity Of Silver Nanoparticles Utilizing Novel Nostoc sp. Bahar M</p>" @default.
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- W2989700058 doi "https://doi.org/10.2147/ijn.s230457" @default.
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