Matches in SemOpenAlex for { <https://semopenalex.org/work/W2989741982> ?p ?o ?g. }
- W2989741982 endingPage "734797" @default.
- W2989741982 startingPage "734797" @default.
- W2989741982 abstract "Abstract C-type lectins (CTLs) are vital molecules in crustacean innate immunity with the capacity to recognize and eliminate invaders, such as viruses and bacteria. Here, two novel CTLs were identified from the kuruma shrimp Marsupenaeus japonicus, and their molecular characteristics and immune function were investigated. Sequence analysis revealed that the two CTLs possessed the typical CTL structure and function features. Tissue distribution analysis showed that the two CTLs were most abundantly expressed in the hepatopancreas and weakly expressed in other examined tissues. The transcription of the two CTLs significantly increased in the hepatopancreas of shrimp challenged with both white spot syndrome virus (WSSV) and Vibrio parahaemolyticus, and MjCTL4 was found to be more sensitive to the two pathogens than MjCTL3, being induced at relatively faster and higher increments. GST pull-down assays showed that the two CTLs could directly interact with several WSSV envelope proteins (VP19, VP24, VP26 and VP28). Moreover, the two CTLs displayed obvious binding and antibacterial ability to V. parahaemolyticus, and MjCTL3 exhibited stronger anti-V. parahaemolyticus activity than MjCTL4. These results suggest that the two novel CTLs might function as pattern recognition receptors (PRRs) and antibacterial molecules in M. japonicus innate immunity, and the two CTLs may be alternative agents for the prevention and treatment of diseases caused by WSSV and V. parahaemolyticus." @default.
- W2989741982 created "2019-12-05" @default.
- W2989741982 creator A5008924675 @default.
- W2989741982 creator A5041505936 @default.
- W2989741982 creator A5071642585 @default.
- W2989741982 creator A5077168485 @default.
- W2989741982 date "2020-03-01" @default.
- W2989741982 modified "2023-09-24" @default.
- W2989741982 title "Identification of two novel C-type lectins involved in immune defense against white spot syndrome virus and Vibrio parahaemolyticus from Marsupenaeus japonicus" @default.
- W2989741982 cites W1966155264 @default.
- W2989741982 cites W1967361018 @default.
- W2989741982 cites W1973027995 @default.
- W2989741982 cites W1973658789 @default.
- W2989741982 cites W1977334325 @default.
- W2989741982 cites W1985681317 @default.
- W2989741982 cites W1987022984 @default.
- W2989741982 cites W1988940244 @default.
- W2989741982 cites W1993211893 @default.
- W2989741982 cites W1993894009 @default.
- W2989741982 cites W2004601087 @default.
- W2989741982 cites W2029367279 @default.
- W2989741982 cites W2030556925 @default.
- W2989741982 cites W2030791299 @default.
- W2989741982 cites W2036920929 @default.
- W2989741982 cites W2040642580 @default.
- W2989741982 cites W2045123850 @default.
- W2989741982 cites W2047517144 @default.
- W2989741982 cites W2048217707 @default.
- W2989741982 cites W2059905270 @default.
- W2989741982 cites W2063333441 @default.
- W2989741982 cites W2064722312 @default.
- W2989741982 cites W2067542513 @default.
- W2989741982 cites W2070993952 @default.
- W2989741982 cites W2073179965 @default.
- W2989741982 cites W2081764012 @default.
- W2989741982 cites W2085479869 @default.
- W2989741982 cites W2088808709 @default.
- W2989741982 cites W2099620792 @default.
- W2989741982 cites W2107277218 @default.
- W2989741982 cites W2119456864 @default.
- W2989741982 cites W2125709515 @default.
- W2989741982 cites W2132901948 @default.
- W2989741982 cites W2139174805 @default.
- W2989741982 cites W2141336068 @default.
- W2989741982 cites W2149233086 @default.
- W2989741982 cites W2170483035 @default.
- W2989741982 cites W2170815160 @default.
- W2989741982 cites W2172377009 @default.
- W2989741982 cites W2189896270 @default.
- W2989741982 cites W2269535426 @default.
- W2989741982 cites W2276088834 @default.
- W2989741982 cites W2328218129 @default.
- W2989741982 cites W2342145395 @default.
- W2989741982 cites W2554141441 @default.
- W2989741982 cites W2740926989 @default.
- W2989741982 cites W2767977144 @default.
- W2989741982 cites W2780816477 @default.
- W2989741982 doi "https://doi.org/10.1016/j.aquaculture.2019.734797" @default.
- W2989741982 hasPublicationYear "2020" @default.
- W2989741982 type Work @default.
- W2989741982 sameAs 2989741982 @default.
- W2989741982 citedByCount "12" @default.
- W2989741982 countsByYear W29897419822020 @default.
- W2989741982 countsByYear W29897419822021 @default.
- W2989741982 countsByYear W29897419822022 @default.
- W2989741982 countsByYear W29897419822023 @default.
- W2989741982 crossrefType "journal-article" @default.
- W2989741982 hasAuthorship W2989741982A5008924675 @default.
- W2989741982 hasAuthorship W2989741982A5041505936 @default.
- W2989741982 hasAuthorship W2989741982A5071642585 @default.
- W2989741982 hasAuthorship W2989741982A5077168485 @default.
- W2989741982 hasConcept C104317684 @default.
- W2989741982 hasConcept C116834253 @default.
- W2989741982 hasConcept C159047783 @default.
- W2989741982 hasConcept C18903297 @default.
- W2989741982 hasConcept C203014093 @default.
- W2989741982 hasConcept C2522874641 @default.
- W2989741982 hasConcept C2776154503 @default.
- W2989741982 hasConcept C2776575720 @default.
- W2989741982 hasConcept C2779771762 @default.
- W2989741982 hasConcept C523546767 @default.
- W2989741982 hasConcept C54355233 @default.
- W2989741982 hasConcept C56273599 @default.
- W2989741982 hasConcept C86803240 @default.
- W2989741982 hasConcept C8891405 @default.
- W2989741982 hasConcept C89423630 @default.
- W2989741982 hasConceptScore W2989741982C104317684 @default.
- W2989741982 hasConceptScore W2989741982C116834253 @default.
- W2989741982 hasConceptScore W2989741982C159047783 @default.
- W2989741982 hasConceptScore W2989741982C18903297 @default.
- W2989741982 hasConceptScore W2989741982C203014093 @default.
- W2989741982 hasConceptScore W2989741982C2522874641 @default.
- W2989741982 hasConceptScore W2989741982C2776154503 @default.
- W2989741982 hasConceptScore W2989741982C2776575720 @default.
- W2989741982 hasConceptScore W2989741982C2779771762 @default.
- W2989741982 hasConceptScore W2989741982C523546767 @default.
- W2989741982 hasConceptScore W2989741982C54355233 @default.
- W2989741982 hasConceptScore W2989741982C56273599 @default.