FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2989744402> ?p ?o ?g. }

• W2989744402 endingPage "2003" @default.
• W2989744402 startingPage "1996" @default.
• W2989744402 abstract "Using handheld spectral domain optical coherence tomography (SDOCT) imaging to investigate in vivo microanatomic retinal changes and their progression over time in young children with juvenile X-linked retinoschisis (XLRS).This retrospective analysis was of handheld SD OCT images obtained under a prospective research protocol in children who had established XLRS diagnosis based on genetic testing or clinical history. Three OCT graders performed standardized qualitative and quantitative assessment of retinal volume scans, which were divided into foveal, parafoveal, and extrafoveal regions. Visual acuity data were obtained when possible.Spectral domain OCT images were available of both eyes in 8 pediatric patients with ages 7 months to 10 years. The schisis cavities involved inner nuclear layer in over 90% (15/16) of eyes in all 3 regions. Retinal nerve fiber and ganglion cell layer involvement was present only in the extrafoveal region in 63% (10/16) eyes and outer nuclear and plexiform layer in few others. In 7 children followed over 2 months to 15 months, the location of schisis remained consistent. Central foveal thickness decreased from the baseline to final available visit in 4/6 eyes. Ellipsoid zone disruption seemed to accompany lower visual acuity in 1/4 eyes.Early in life, the SD OCT findings in XLRS demonstrate differences in schisis location in fovea-parafoveal versus extrafoveal region, possible association between poor visual acuity and degree of ellipsoid zone disruption and decrease in central foveal thickness over time in this group. Furthermore, they illustrates that the pattern of XLRS in adults is already present in very young children, and unlike in older children and adults, those presenting with earlier disease may have a more aggressive course. Further studies in this early age group may provide more insights into treatment and prevention of progressive visual impairment in children with XLRS." @default.
• W2989744402 created "2019-12-05" @default.
• W2989744402 creator A5001380413 @default.
• W2989744402 creator A5016490722 @default.
• W2989744402 creator A5064085171 @default.
• W2989744402 creator A5078534469 @default.
• W2989744402 creator A5082958339 @default.
• W2989744402 creator A5090512897 @default.
• W2989744402 date "2019-11-21" @default.
• W2989744402 modified "2023-10-16" @default.
• W2989744402 title "HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS OF X-LINKED RETINOSCHISIS IN EARLY CHILDHOOD" @default.
• W2989744402 cites W133322113 @default.
• W2989744402 cites W1500137773 @default.
• W2989744402 cites W1833180266 @default.
• W2989744402 cites W1968325849 @default.
• W2989744402 cites W1976026899 @default.
• W2989744402 cites W1977051627 @default.
• W2989744402 cites W1987055248 @default.
• W2989744402 cites W1996386536 @default.
• W2989744402 cites W2004437347 @default.
• W2989744402 cites W2023623463 @default.
• W2989744402 cites W2030718895 @default.
• W2989744402 cites W2030859527 @default.
• W2989744402 cites W2036734025 @default.
• W2989744402 cites W2038937988 @default.
• W2989744402 cites W2039553905 @default.
• W2989744402 cites W2042534215 @default.
• W2989744402 cites W2050285651 @default.
• W2989744402 cites W2050434311 @default.
• W2989744402 cites W2053246781 @default.
• W2989744402 cites W2061105073 @default.
• W2989744402 cites W2063508257 @default.
• W2989744402 cites W2069699955 @default.
• W2989744402 cites W2078717021 @default.
• W2989744402 cites W2083114217 @default.
• W2989744402 cites W2085545818 @default.
• W2989744402 cites W2092997453 @default.
• W2989744402 cites W2096257125 @default.
• W2989744402 cites W2130486373 @default.
• W2989744402 cites W2130950303 @default.
• W2989744402 cites W2143691781 @default.
• W2989744402 cites W2146551910 @default.
• W2989744402 cites W2148445098 @default.
• W2989744402 cites W2154221129 @default.
• W2989744402 cites W2162930631 @default.
• W2989744402 cites W2163174962 @default.
• W2989744402 cites W2164627723 @default.
• W2989744402 cites W2195054952 @default.
• W2989744402 cites W2329590647 @default.
• W2989744402 cites W2330576483 @default.
• W2989744402 doi "https://doi.org/10.1097/iae.0000000000002688" @default.
• W2989744402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31764609" @default.
• W2989744402 hasPublicationYear "2019" @default.
• W2989744402 type Work @default.
• W2989744402 sameAs 2989744402 @default.
• W2989744402 citedByCount "15" @default.
• W2989744402 countsByYear W29897444022020 @default.
• W2989744402 countsByYear W29897444022021 @default.
• W2989744402 countsByYear W29897444022022 @default.
• W2989744402 countsByYear W29897444022023 @default.
• W2989744402 crossrefType "journal-article" @default.
• W2989744402 hasAuthorship W2989744402A5001380413 @default.
• W2989744402 hasAuthorship W2989744402A5016490722 @default.
• W2989744402 hasAuthorship W2989744402A5064085171 @default.
• W2989744402 hasAuthorship W2989744402A5078534469 @default.
• W2989744402 hasAuthorship W2989744402A5082958339 @default.
• W2989744402 hasAuthorship W2989744402A5090512897 @default.
• W2989744402 hasBestOaLocation W29897444022 @default.
• W2989744402 hasConcept C118487528 @default.
• W2989744402 hasConcept C2777585161 @default.
• W2989744402 hasConcept C2778231335 @default.
• W2989744402 hasConcept C2778257484 @default.
• W2989744402 hasConcept C2778818243 @default.
• W2989744402 hasConcept C2779594218 @default.
• W2989744402 hasConcept C2779736970 @default.
• W2989744402 hasConcept C2780428090 @default.
• W2989744402 hasConcept C2780827179 @default.
• W2989744402 hasConcept C30181142 @default.
• W2989744402 hasConcept C71924100 @default.
• W2989744402 hasConceptScore W2989744402C118487528 @default.
• W2989744402 hasConceptScore W2989744402C2777585161 @default.
• W2989744402 hasConceptScore W2989744402C2778231335 @default.
• W2989744402 hasConceptScore W2989744402C2778257484 @default.
• W2989744402 hasConceptScore W2989744402C2778818243 @default.
• W2989744402 hasConceptScore W2989744402C2779594218 @default.
• W2989744402 hasConceptScore W2989744402C2779736970 @default.
• W2989744402 hasConceptScore W2989744402C2780428090 @default.
• W2989744402 hasConceptScore W2989744402C2780827179 @default.
• W2989744402 hasConceptScore W2989744402C30181142 @default.
• W2989744402 hasConceptScore W2989744402C71924100 @default.
• W2989744402 hasIssue "10" @default.
• W2989744402 hasLocation W29897444021 @default.
• W2989744402 hasLocation W29897444022 @default.
• W2989744402 hasLocation W29897444023 @default.
• W2989744402 hasOpenAccess W2989744402 @default.
• W2989744402 hasPrimaryLocation W29897444021 @default.
• W2989744402 hasRelatedWork W1969315744 @default.
• W2989744402 hasRelatedWork W1977786295 @default.

• next