FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2989746808> ?p ?o ?g. }

• W2989746808 abstract "Abstract Long-term management for leukemia is challenging due to the painful and invasive procedure of bone marrow (BM) biopsy. At present, non-invasive liquid (blood) biopsy is not utilized for leukemia, due to lower counts of leukemia blast cells in the blood. Here, we described a robust system for the simultaneous detection and enrichment of rare blast cells. Enrichment of blast cells was achieved from blood with a one-step microfluidic blast cell biochip (BCB) sorting system, without specific targeting of proteins by antibodies. Non-target cells encountered a differential net force as compared to stiffer blast cells and were removed. The efficiency of the BCB promotes high detection sensitivity (1 in 10 6 cells) even from patients with minimal residual disease. The procedure was validated using actual blast cells from patients with various types of leukemia. Outcomes were compared to current evaluation standards, such as flow cytometry, using BM aspirates. Blast cell detection efficiency was higher in 55.6% of the patients using the BCB as compared to flow cytometry, despite the lower concentrations of blast cells in liquid biopsy. These studies promote early-stage detection and routine monitoring for minimal residual disease in patients." @default.
• W2989746808 created "2019-12-05" @default.
• W2989746808 creator A5031498697 @default.
• W2989746808 creator A5031891367 @default.
• W2989746808 creator A5036772787 @default.
• W2989746808 creator A5039828232 @default.
• W2989746808 creator A5066282840 @default.
• W2989746808 creator A5089893814 @default.
• W2989746808 date "2019-12-02" @default.
• W2989746808 modified "2023-10-17" @default.
• W2989746808 title "Liquid biopsy for minimal residual disease detection in leukemia using a portable blast cell biochip" @default.
• W2989746808 cites W1631320694 @default.
• W2989746808 cites W1918057567 @default.
• W2989746808 cites W1926629237 @default.
• W2989746808 cites W1966810382 @default.
• W2989746808 cites W1974541126 @default.
• W2989746808 cites W1977594022 @default.
• W2989746808 cites W1982656232 @default.
• W2989746808 cites W1990961911 @default.
• W2989746808 cites W1994179662 @default.
• W2989746808 cites W2009886857 @default.
• W2989746808 cites W2024468612 @default.
• W2989746808 cites W2043755974 @default.
• W2989746808 cites W2050547995 @default.
• W2989746808 cites W2053657011 @default.
• W2989746808 cites W2055448421 @default.
• W2989746808 cites W2056163905 @default.
• W2989746808 cites W2075026686 @default.
• W2989746808 cites W2078704378 @default.
• W2989746808 cites W2086187432 @default.
• W2989746808 cites W2089906568 @default.
• W2989746808 cites W2097950721 @default.
• W2989746808 cites W2106282095 @default.
• W2989746808 cites W2116858301 @default.
• W2989746808 cites W2143835472 @default.
• W2989746808 cites W2143843041 @default.
• W2989746808 cites W2207498669 @default.
• W2989746808 cites W2290517386 @default.
• W2989746808 cites W2308980451 @default.
• W2989746808 cites W2418545856 @default.
• W2989746808 cites W2791825397 @default.
• W2989746808 doi "https://doi.org/10.1038/s41698-019-0102-5" @default.
• W2989746808 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6889137" @default.
• W2989746808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31815186" @default.
• W2989746808 hasPublicationYear "2019" @default.
• W2989746808 type Work @default.
• W2989746808 sameAs 2989746808 @default.
• W2989746808 citedByCount "21" @default.
• W2989746808 countsByYear W29897468082020 @default.
• W2989746808 countsByYear W29897468082021 @default.
• W2989746808 countsByYear W29897468082022 @default.
• W2989746808 countsByYear W29897468082023 @default.
• W2989746808 crossrefType "journal-article" @default.
• W2989746808 hasAuthorship W2989746808A5031498697 @default.
• W2989746808 hasAuthorship W2989746808A5031891367 @default.
• W2989746808 hasAuthorship W2989746808A5036772787 @default.
• W2989746808 hasAuthorship W2989746808A5039828232 @default.
• W2989746808 hasAuthorship W2989746808A5066282840 @default.
• W2989746808 hasAuthorship W2989746808A5089893814 @default.
• W2989746808 hasBestOaLocation W29897468081 @default.
• W2989746808 hasConcept C124964019 @default.
• W2989746808 hasConcept C142724271 @default.
• W2989746808 hasConcept C1491633281 @default.
• W2989746808 hasConcept C203014093 @default.
• W2989746808 hasConcept C2775934546 @default.
• W2989746808 hasConcept C2778461978 @default.
• W2989746808 hasConcept C2778729363 @default.
• W2989746808 hasConcept C2779823535 @default.
• W2989746808 hasConcept C2780007613 @default.
• W2989746808 hasConcept C2780339063 @default.
• W2989746808 hasConcept C502942594 @default.
• W2989746808 hasConcept C54355233 @default.
• W2989746808 hasConcept C553184892 @default.
• W2989746808 hasConcept C60644358 @default.
• W2989746808 hasConcept C71924100 @default.
• W2989746808 hasConcept C86803240 @default.
• W2989746808 hasConcept C87892846 @default.
• W2989746808 hasConceptScore W2989746808C124964019 @default.
• W2989746808 hasConceptScore W2989746808C142724271 @default.
• W2989746808 hasConceptScore W2989746808C1491633281 @default.
• W2989746808 hasConceptScore W2989746808C203014093 @default.
• W2989746808 hasConceptScore W2989746808C2775934546 @default.
• W2989746808 hasConceptScore W2989746808C2778461978 @default.
• W2989746808 hasConceptScore W2989746808C2778729363 @default.
• W2989746808 hasConceptScore W2989746808C2779823535 @default.
• W2989746808 hasConceptScore W2989746808C2780007613 @default.
• W2989746808 hasConceptScore W2989746808C2780339063 @default.
• W2989746808 hasConceptScore W2989746808C502942594 @default.
• W2989746808 hasConceptScore W2989746808C54355233 @default.
• W2989746808 hasConceptScore W2989746808C553184892 @default.
• W2989746808 hasConceptScore W2989746808C60644358 @default.
• W2989746808 hasConceptScore W2989746808C71924100 @default.
• W2989746808 hasConceptScore W2989746808C86803240 @default.
• W2989746808 hasConceptScore W2989746808C87892846 @default.
• W2989746808 hasFunder F4320313201 @default.
• W2989746808 hasFunder F4320320751 @default.
• W2989746808 hasFunder F4320320765 @default.
• W2989746808 hasIssue "1" @default.
• W2989746808 hasLocation W29897468081 @default.
• W2989746808 hasLocation W29897468082 @default.

• next