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- W2989757672 abstract "Infection of adult mice with the clone 13 (CL13) strain of lymphocytic choriomeningitis virus (LCMV) is extensively used as a model of chronic infection. In this paper, we show that mice chronically infected with CL13 succumb to challenge with ectromelia virus (ECTV; the agent of mousepox) and that natural killer (NK) cells in CL13-infected mice are reduced in numbers and have an immature and partially activated phenotype but do respond to ECTV. These data may provide additional clues why humans chronically infected with certain pathogens are less resistant to viral diseases." @default.
- W2989757672 created "2019-12-05" @default.
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- W2989757672 date "2020-02-14" @default.
- W2989757672 modified "2023-10-17" @default.
- W2989757672 title "Chronic Lymphocytic Choriomeningitis Infection Causes Susceptibility to Mousepox and Impairs Natural Killer Cell Maturation and Function" @default.
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- W2989757672 doi "https://doi.org/10.1128/jvi.01831-19" @default.
- W2989757672 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7022367" @default.
- W2989757672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31776282" @default.
- W2989757672 hasPublicationYear "2020" @default.
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