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- W2989968362 abstract "Abstract Background The survival of patients with nasopharyngeal cancer (NPC) have been reported in endemic and non-endemic regions. However, this has never been analyzed in Indonesian cases although this malignancy is endemic. This study aimed to perform survival analysis of the local cases and determine the prognostic factors. Methods A total of 767 patients with NPC diagnosed from January 2007 to December 2016 at Dr Sardjito General Hospital were included. Potential prognostic variables included sociodemographic parameters, clinicopathology features and treatment strategy. Kaplan-Meier method and the log-rank test estimated the rates of overall survival (OS). Multivariate analyses were done by a Cox proportional hazards model. Results The median OS was 14.38 months for the whole cohort. Patients with education ≥9 years, government insurance for civil servants, advanced stage and combination of chemo-radiation treatment had a significantly better OS than their counterparts (p Conclusions Median OS of our cohort was low compared to those reported in international publications, emphasizing the importance to improve the local cancer management. Age, clinical stage and treatment modality were independent favourable predictos for the patients’ OS. Legal entity responsible for the study Ethics committee, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr Sardjito Hospital. Funding Indonesian Society for Hematology and Medical Oncology Yogyakarta Branch; Dutch Cancer Society. Disclosure All authors have declared no conflicts of interest." @default.
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- W2989968362 date "2019-11-01" @default.
- W2989968362 modified "2023-10-01" @default.
- W2989968362 title "Survival outcome and prognostic factors of patients with nasopharyngeal cancer in Yogyakarta Indonesia" @default.
- W2989968362 doi "https://doi.org/10.1093/annonc/mdz428.005" @default.
- W2989968362 hasPublicationYear "2019" @default.
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