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• W2989979750 abstract "• Mosquitoes are notorious pests to higher vertebrates and cause millions of death every year. • Citrus limetta leaf methanol extract (LME) and its major phyto-compound (MPC) had significant toxic effect for controlling vector mosquitoes and it could generate a healthy environment. • The phyto-compounds were identified by different spectral analysis like GC–MS, Mass spectrum and FT-IR. • The MPC, Corynan-17-0l,18,19-didehydro-10-methoxy-,acelate (ester) had noteworthy mosquitocidal activity and less toxic effects and safer for the selected non-target organisms. In the present study, Citrus limetta major phyto-compound (MPC) was identified from leaf methanolic extract (LME) through different spectral analysis such as GC–MS, Mass spectrum and FT-IR. The MPC of Corynan-17-0l,18,19-didehydro-10-methoxy-,acelate (ester) isolated from LME was tested with various concentrations (10–90 μg/mL) against 3rd instars mosquito larvae of Aedes albopictus, Anopheles maculatus and Culex mimulus under laboratory condition by using the standard protocol. GC–MS analysis of LME revealed the presence of six phyto-compounds of which, Corynan-17-0l,18,19-didehydro-10-methoxy-,acelate (ester) (C 22 H 28 N 2 O 3 ) was found as MPC (39.01%). MS analysis supports the existence of MPC. Further, FTIR spectral data was used to find and confirm the exact functional group(s). The LC 50 values of LME and MPC were recorded as 15.56, 13.72, 11.45 and 88.21, 86.49 and 79.72 μg/mL respectively. Moreover, less susceptible and higher suitability index were noticed on aquatic non-target fauna (NTF). We hypothesized that C. limetta LME and MPC of Corynan-17-0l,18,19-didehydro-10-methoxy-,acelate (ester) could be the important element, responsible for the larval toxicity. This suty promises an eco-friendly approach for the control of human vector mosquitoes (HVMs) and least toxic effects on non-target fauna (NTF)." @default.
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• W2989979750 date "2020-01-01" @default.
• W2989979750 modified "2023-09-29" @default.
• W2989979750 title "Citrus limetta (Risso) - borne compound as novel mosquitocides: Effectiveness against medical pest and acute toxicity on non-target fauna" @default.
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• W2989979750 doi "https://doi.org/10.1016/j.sajb.2019.11.014" @default.
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